Loss of Down syndrome critical region-1 leads to cholesterol metabolic dysfunction that exaggerates hypercholesterolemia in ApoE-null background

Abstract

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FOXO1 stimulates tip cell-enriched gene expression in endothelial cells

“…Extraction and fractionation of nuclear and cytoplasmic proteins were performed as described previously. 49 The antibodies used for the western blotting were as follows: FOXO1, Ser256 phosphorylated FOXO1, β-actin, lamin A, and β-tubulin. HRP-conjugated secondary antibodies used were anti-rabbit IgG and anti-mouse IgG.…”