Abstract:The innate immune system (IIS) is the first line of defense against infectious agents and the detection of tissue damage. The IIS recognizes a group of molecules essential for the survival of microorganisms, which are called pathogen-associated molecular patterns (PAMPs). In addition, IIS recognizes molecules produced and released by damaged or stressed cells, called damage associated molecular patterns (DAMPs). Both PAMPs and DAMPs are recognized by a group of evolutionarily conserved receptors on IIS cells c… Show more
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