“…In this work, we compute the Casimir energy stored in the genome cylindrical-like segment corresponding to a helical pitch of the RNA molecule, then particularize the calculations to the SARS-CoV-2. For this, we will initially consider the quantum vacuum fluctuations of a scalar field under helix boundary conditions, in accordance with Feng and Li, 2020 , Aleixo and Mota, 2021 and Farias Junior and Santana Mota (2022) , extending the results to an electromagnetic field. In this context, in order to consider the most realistic situation, in our investigation we considered the UV-A and -C radiations as the threshold energy, since UV, during the day, is abundantly provided by the sun.…”