Look how far we have come: BREAST cancer detection education on the international stage

Abstract

The development of screening mammography over 30 years has remarkedly reduced breast cancer–associated mortality by 20%-30% through detection of small cancer lesions at early stages. Yet breast screening programmes may function differently in each nation depending on the incidence rate, national legislation, local health infrastructure and training opportunities including feedback on performance. Mammography has been the frontline breast cancer screening tool for several decades; however, it is estimated that there are 15% to 35% of cancers missed on screening which are owing to perceptual and decision-making errors by radiologists and other readers. Furthermore, mammography screening is not available in all countries and the increased speed in the number of new breast cancer cases among less developed countries exceeds that of the developed world in recent decades. Studies conducted through the BreastScreen Reader Assessment Strategy (BREAST) training tools for breast screening readers have documented benchmarking and significant variation in diagnostic performances in screening mammogram test sets in different countries. The performance of the radiologists from less well-established breast screening countries such as China, Mongolia and Vietnam were significant lower in detecting early-stage cancers than radiologists from developed countries such as Australia, USA, Singapore, Italy. Differences in breast features and cancer presentations, discrepancies in the level of experiences in reading screening mammograms, the availability of high-quality national breast screening program and breast image interpretation training courses between developed and less developed countries are likely to have impact on the variation of readers’ performances. Hence dedicated education training programs with the ability to tailor to different reader cohorts and different population presentations are suggested to ameliorate challenges in exposure to a range of cancer cases and improve the interpretation skills of local radiologists. Findings from this review provide a good understanding of the radiologist’ performances and their improvement using the education interventions, primarily the BREAST program, which has been deployed in a large range of developing and developed countries in the last decade. Self-testing and immediate feedback loops have been shown to have important implications for benchmarking and improving the diagnostic accuracy in radiology worldwide for better breast cancer control.

Factors associated with financial toxicity in patients with breast cancer in Japan: a comparison of patient and physician perspectives

“…The number of patients diagnosed with breast cancer is increasing annually [ 1 , 2 ], emphasizing the need for improved screening accuracy [ 3 , 4 ], comprehensive treatment methods, and personalized treatments [ 2 , 5 ]. However, patients with breast cancer tend to be younger than those with other cancers [ 6 , 7 ], resulting in direct burdens, such as longer treatment periods and increased costs [ 8 , 9 ], as well as indirect burdens, such as adverse event treatments [ 10 ], fertility preservation [ 11 , 12 ], and lost earnings [ 13 ].…”

Variations of image interpretations of radiologists from different populations in mammography and tomosynthesis with different levels of breast density

“…A dedicated training program with specialized tutorials instructed by breast screening experts and access to self-evaluation mammogram sets with enriched abnormal cases have been suggested to ameliorate the prevalence impact and improve the interpretation skills of local radiologists 39 . The BREAST program has been shown to be an effective training platform for Australian radiologists and radiology trainees in mammographic screening interpretation 20 , 40 , 41 and has demonstrated an improvement in radiologists’ cancer detection in real-world screening programs, 42 , 43 which strongly suggests that the adoption of this type of training could enhance Shanghai radiologists’ skills and improve health outcomes for Chinese women. This has been previously shown by our work in Vietnam, which indicated that the diagnostic performance of local radiologists in detecting small abnormal lesions, such as stellate or spiculated masses, can be increased if a proper training intervention is applied 39 …”

CXC ELR-Positive Chemokines as Diagnostic and Prognostic Markers for Breast Cancer Patients

“…Implementing mammography screening in many countries for groups of women with an increased risk of breast cancer, that is, around the age of 50, was a breakthrough in streamlining the diagnostic process. Many studies have shown a significant decrease in the risk of breast cancer mortality after introducing mammography into medical practice [ 3 , 4 ]. However, imaging methods also have limitations.…”