Longitudinally extensive transverse myelitis with aquaporin-4 antibody after herpes zoster: A case report

Abstract

Varicella zoster virus (VZV) is human neurotropic virus. It becomes latent in dorsal root ganglia; it may reactivate and can cause dermatological manifestations; most common is herpes zoster. Several neurological disorders can occur such as encephalitis, meningitis, myelitis and neuropathy. Longitudinally extensive transverse myelitis is infrequent.The association of AQP4 antibody with Varicella zoster has been documented in few case reports. Here we report a case of young woman who developed longitudinally extensive transverse myelitis with positive AQP4 antibody titers following varicella zoster infection.