Longitudinal trends in quality of life after starting home parenteral nutrition: A randomised controlled study of telemedicine

Chambers, Alison; Hennessy, Enid; Powell-Tuck, J

doi:10.1016/j.clnu.2006.01.001

Cited by 31 publications

(75 citation statements)

References 16 publications

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“…Similarly, Malone 63 evaluated 13 individuals receiving home PN for a mean of 7.1 years and reported no difference in Short‐Form (36) Health Survey (SF‐36) scores at 3‐year intervals. Conversely, Chambers et al, 64 using the SF‐36, demonstrated an increase in QOL scores (domains of physical function, vitality, social function, emotional role, and mental health) for 30 individuals with short bowel syndrome after 6 months of home PN but no change in scores for the domains of bodily pain, general health, or physical component summary. Regardless of length of home PN dependency in the present study, participants perceived that life “could be a heck of a lot worse.” In addition, using downward social comparison (the process of comparing oneself to someone worse off), 65 , 66 participants saw their own situation as better than others who had a physical disability or cancer.…”

Section: Discussionmentioning

confidence: 95%

“…First, because of the exclusion criteria, none of the study participants had a diagnosis of depression or received palliative care. Prior research clearly demonstrates a relationship between narcotic dependency, depression, and worse QOL for individuals receiving home PN 48 , 51 , 63 , 64 . Second, studies using the SF‐36 to measure QOL identified a wide range of scores in the physical function domain and the inability to work full‐time as an influencing factor 8 , 50 , 52 , 53 , 55 , 63 .…”

Section: Discussionmentioning

confidence: 99%

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An Exploration of Quality of Life and the Experience of Living With Home Parenteral Nutrition

Winkler

Hagan

Wetle

et al. 2010

J Parenter Enteral Nutr

112

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

An Exploration of Quality of Life and the Experience of Living With Home Parenteral Nutrition

Winkler

Hagan

Wetle

et al. 2010

J Parenter Enteral Nutr

112

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“…1 HPN provides improved quality of life with lower cost than inpatient parenteral nutrition (PN). 2–5 HPN has been purported to offer similar rehabilitation and complication outcomes compared with inpatient PN. 6–9 …”

Section: Introductionmentioning

confidence: 99%

A Descriptive Study of the Risk Factors Associated With Catheter‐Related Bloodstream Infections in the Home Parenteral Nutrition Population

Durkin

Dukes

Reeds

et al. 2015

J Parenter Enteral Nutr

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Background Home parenteral nutrition (HPN) is increasingly used for nutrition support after patients are discharged from the hospital. Catheter-related bloodstream infections (CR-BSI) are a common and potentially fatal complication of HPN. The risk factors for development of CR-BSI in the outpatient setting are poorly understood. Methods We conducted an observational, retrospective study of 225 patients discharged from Barnes-Jewish Hospital on HPN between January 1, 2007, and December 31, 2009. HPN complications were defined as any cause that led to either premature discontinuation of HPN therapy or catheter replacement. CR-BSI events were identified by provider documentation. We calculated the overall complication rate and the complication rate specifically due to CR-BSI. Backward stepwise Cox regression analyses were used to assess for independent predictors of catheter-related complications. Results In total, 111 of 225 patients (49%) developed complications while receiving HPN (incidence = 5.06 episodes/1000 catheter days). Sixty-eight of 225 patients (30%) required catheter removal for CR-BSI (incidence = 3.10 episodes/1000 catheter days). Independent predictors of line removal specifically due to infection included anticoagulant use, ulcer or open wound, and Medicare or Medicaid insurance. The following risk factors were associated with catheter-associated complications and/or CR-BSI: the presence of ulcers, the use of systemic anticoagulants, public insurance (Medicare or Medicaid), and patient age. Independent predictors of line removal for any complication included age and anticoagulant use. Conclusion Catheter-related complications were extremely common in patients receiving HPN. Healthcare providers caring for individuals who require home TPN should be aware of risk factors for complications.

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“…Chambers et al [33 ] described longitudinal trends in QoL after starting HPN in a group of 30 patients. QoL scores, which were significantly lower than normative data at discharge, improved over the first 6 months in the domains of physical functioning, physical role, vitality, social functioning, emotional role domains and mental component summary.…”

Section: Prognosis and Quality Of Lifementioning

confidence: 99%

Home parenteral nutrition in adults

Gossum

2007

Current Opinion in Organ Transplantation

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Complications include catheter-related sepsis and thrombosis, metabolic disorders, nutritional deficiency, psychological alteration and rehabilitation problems. Recent studies found that catheters lasted for 1.5 years on average. Alteration in hepatic enzymes alterations is frequent but severe liver complications are rare. Bone alterations occur in 75% of HPN patients, with multifactorial aetiology. Lipid administration should not exceed 1 g/kg per day. Overall probability of survival is good at 1 and 10 years; 10% of deaths are due to HPN complications. A large survey in European centres revealed that 15% of adults and 34% of children are candidates for intestinal transplantation.

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Longitudinal trends in quality of life after starting home parenteral nutrition: A randomised controlled study of telemedicine

Cited by 31 publications

References 16 publications

An Exploration of Quality of Life and the Experience of Living With Home Parenteral Nutrition

An Exploration of Quality of Life and the Experience of Living With Home Parenteral Nutrition

A Descriptive Study of the Risk Factors Associated With Catheter‐Related Bloodstream Infections in the Home Parenteral Nutrition Population

Home parenteral nutrition in adults

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