Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5 T MR-linear accelerator hybrid system: A prospective R-IDEAL stage 2a imaging biomarker characterization/pre-qualification study

El-Habashy, Dina; Wahid, Kareem A.; He, Renjie; McDonald, Brigid A.; Rigert, Jillian; Mulder, Samuel J.; Lim, Tze Yee; Wang, Xin; Yang, Jinzhong; Ding, Yao; Naser, Mohamed A.; Ng, Sweet Ping; Bahig, Houda; Salzillo, Travis C.; Preston, Kathryn; Abobakr, Moamen; Shehata, Mohamed; Elkhouly, E.A.; Alagizy, Hagar A.; Hegazy, Ahmed; Mohammadseid, Mustefa; Terhaard, Chris H.J.; Philippens, M.E.P.; Rosenthal, David I.; Wang, Jihong; Lai, Stephen Y.; Dresner, Alex; Christodouleas, John; Mohamed, A.S.R.; Fuller, Clifton D.

doi:10.1016/j.ctro.2023.100666

Clinical and Translational Radiation Oncology

2023

DOI: 10.1016/j.ctro.2023.100666

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Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5 T MR-linear accelerator hybrid system: A prospective R-IDEAL stage 2a imaging biomarker characterization/pre-qualification study

Dina El-Habashy¹,

Kareem A. Wahid²,

Renjie He³

et al.

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2024

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Dataset of weekly intra-treatment diffusion weighted imaging in head and neck cancer patients treated with MR-Linac

El-Habashy,

Wahid,

et al. 2024

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Radiation therapy (RT) is a crucial treatment for head and neck squamous cell carcinoma (HNSCC); however, it can have adverse effects on patients’ long-term function and quality of life. Biomarkers that can predict tumor response to RT are being explored to personalize treatment and improve outcomes. While tissue and blood biomarkers have limitations, imaging biomarkers derived from magnetic resonance imaging (MRI) offer detailed information. The integration of MRI and a linear accelerator in the MR-Linac system allows for MR-guided radiation therapy (MRgRT), offering precise visualization and treatment delivery. This data descriptor offers a valuable repository for weekly intra-treatment diffusion-weighted imaging (DWI) data obtained from head and neck cancer patients. By analyzing the sequential DWI changes and their correlation with treatment response, as well as oncological and survival outcomes, the study provides valuable insights into the clinical implications of DWI in HNSCC.

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Dataset of weekly intra-treatment diffusion weighted imaging in head and neck cancer patients treated with MR-Linac

El-Habashy,

Wahid,

et al. 2024

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Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5 T MR-linear accelerator hybrid system: A prospective R-IDEAL stage 2a imaging biomarker characterization/pre-qualification study

Cited by 1 publication

References 30 publications

Dataset of weekly intra-treatment diffusion weighted imaging in head and neck cancer patients treated with MR-Linac

Dataset of weekly intra-treatment diffusion weighted imaging in head and neck cancer patients treated with MR-Linac

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Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5 T MR-linear accelerator hybrid system: A prospective R-IDEAL stage 2a imaging biomarker characterization/pre-qualification study

Cited by 1 publication

References 30 publications

Dataset of weekly intra-treatment diffusion weighted imaging in head and neck cancer patients treated with MR-Linac

Dataset of weekly intra-treatment diffusion weighted imaging in head and neck cancer patients treated with MR-Linac

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Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5 T MR-linear accelerator hybrid system: A prospective R-IDEAL stage 2a imaging biomarker characterization/pre-qualification study