Longitudinal Cognitive and Physical Training Effectiveness in MCI, Based on the Experience of the Alzheimer’s Hellas Day Care Centre

Poptsi, Eleni; Tsatali, Marianna; Agogiatou, Christina; Bakoglidou, Evaggelia; Batsila, Georgia; Dellaporta, Dionysia; Kounti-Zafeiropoulou, Fotini; Liapi, Despoina; Lysitsas, Konstantinos; Markou, Nefeli; Mouzakidis, Christos; Ouzouni, Fani; Papasozomenou, Chrysa; Soumpourou, Aikaterini; Vasiloglou, Maria F.; Stavros, Zafeiropoulos; Tsolaki, Magda

doi:10.1177/08919887211016057

Cited by 8 publications

(6 citation statements)

References 75 publications

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“…First, our findings highlight the significance of implementing meaningful activities and psychosocial web-based interventions in older adults with MCI as well as ADD in mild and moderate stages, which is also in line with previous evidence [6,14]. Our recent study [41] was partially in line with the current results because we found that deterioration was increased in the MCI population by means of measuring their long-term memory with RAVLT as well as the phonemic verbal test. Therefore, it could be assumed that MCI participants' performance, at least as measured by the aforementioned tests, is not affected by the quarantine.…”

Section: Discussionsupporting

confidence: 92%

Are There Any Cognitive and Behavioral Changes Potentially Related to Quarantine Due to the COVID-19 Pandemic in People with Mild Cognitive Impairment and AD Dementia? A Longitudinal Study

et al. 2021

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The aim of the study was to examine potential cognitive, mood (depression and anxiety) and behavioral changes that may be related to the quarantine and the lockdown applied during the COVID-19 pandemic in Greek older adults with mild cognitive impairment (MCI), and AD dementia in mild and moderate stages. Method: 407 older adults, diagnosed either with MCI or AD dementia (ADD), were recruited from the Day Centers of the Greek Association of Alzheimer Disease and Related Disorders (GAADRD). Neuropsychological assessment was performed at baseline (at the time of diagnosis) between May and July of 2018, as well as for two consecutive follow-up assessments, identical in period, in 2019 and 2020. The majority of participants had participated in non-pharmacological interventions during 2018 as well as 2019, whereas all of them continued their participation online in 2020. Results: Mixed measures analysis of variance showed that participants’ ‘deterioration difference—D’ by means of their performance difference in neuropsychological assessments between 2018–2019 (D1) and 2019–2020 (D2) did not change, except for the FUCAS, RAVLT, and phonemic fluency tests, since both groups resulted in a larger deterioration difference (D2) in these tests. Additionally, three path models examining the direct relationships between performance in tests measuring mood, as well as everyday functioning and cognitive measures, showed that participants’ worsened performance in the 2019 and 2020 assessments was strongly affected by NPI performance, in sharp contrast to the 2018 assessment. Discussion: During the lockdown period, MCI and ADD patients’ neuropsychological performance did not change, except from the tests measuring verbal memory, learning, and phonemic fluency, as well as everyday functioning. However, the natural progression of the MCI as well as ADD condition is the main reason for participants’ deterioration. Mood performance became increasingly closely related to cognition and everyday functioning. Hence, the role of quarantine and AD progression are discussed as potential factors associated with impairments.

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Section: Discussionsupporting

confidence: 92%

Are There Any Cognitive and Behavioral Changes Potentially Related to Quarantine Due to the COVID-19 Pandemic in People with Mild Cognitive Impairment and AD Dementia? A Longitudinal Study

et al. 2021

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“…In recent years, due to the increasing number of people suffering from dementia, brain exercise interventions and delaying cognitive decline in people with MCI have gained considerable attention [ 59 ]. Recent longitudinal findings suggest that structured cognitive interventions can target brain function by increasing cognitive reserve and thus delay the progression of MCI [ 15, 59, 61–63 ]. E.L.So.M.C.I.…”

Section: Discussionmentioning

confidence: 99%

A Novel Method of Teaching English to People with Mild Cognitive Impairment Using Songs: A Randomized Controlled Trial Protocol

Makri

Christakidou

Tsolaki

2023

JAD

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Background: People with mild cognitive impairment (MCI) need to prevent the further decline of their cognitive functions, and one way to do so is by learning a foreign language. Objective: This study describes the development of a protocol for a novel, non-pharmacological intervention for people with MCI that seeks to prevent or reduce cognitive decline by teaching English through songs. Methods: The development of this protocol follows a mixed-methodology approach, consisting of three stages: 1) development of the protocol of the intervention, 2) a randomized controlled trial study with two arms over six months that includes an intervention group and a control group, and 3) the evaluation of the protocol by trainers. In the second stage, we recruited a total of 128 people with MCI from the five participating countries of this study (Greece, Spain, Croatia, Slovenia, and Italy). This educational program will assess three main outcomes after 6 months of the English Lessons with the Use of Songs for People with Mild Cognitive Impairment (E.L.So.M.C.I.) workshops. Results: Our primary outcome will hopefully be an improvement in general cognition in the intervention group compared to the control group from baseline to 6 months follow-up. Secondary outcomes include a decrease in participants’ anxiety and depression and an improvement in their quality of life. Development of English language skills is the third outcome.

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“…59 One study found that 3 years of following a cognitive and physical training intervention seemed to reduce the number of people with MCI who progressed to dementia. 60 New technologies are emerging quickly, and can take on multiple roles; for example, a cognitive training application based on a virtual shopping task not only strengthens memory, planning, and other cognitive skills, but can also be used to screen for MCI. 61,62 The Virtual Supermarket (VSM) test is multilingual and fully self-administered in its latest iteration.…”

Section: Challenges In Dementia Care: Regional Policies and Initiativesmentioning

confidence: 99%

“…In Greece, cognitive stimulation, rehabilitation, and training programs are delivered in day centers 59 . One study found that 3 years of following a cognitive and physical training intervention seemed to reduce the number of people with MCI who progressed to dementia 60 …”

Section: Challenges In Dementia Care: Regional Policies and Initiativesmentioning

confidence: 99%

Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium

Sexton

Solis²,

Aharon‐Peretz

et al. 2022

Alzheimer's & Dementia

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As research and services in the Mediterranean region continue to increase, so do opportunities for global collaboration. To support such collaborations, the Alzheimer's Association was due to hold its seventh Alzheimer's Association International Conference Satellite Symposium in Athens, Greece in 2021. Due to the COVID‐19 pandemic, the meeting was held virtually, which enabled attendees from around the world to hear about research efforts in Greece and the surrounding Mediterranean countries. Research updates spanned understanding the biology of, treatments for, and care of people with Alzheimer's disease (AD_ and other dementias. Researchers in the Mediterranean region have outlined the local epidemiology of AD and dementia, and have identified regional populations that may expedite genetic studies. Development of biomarkers is expected to aid early and accurate diagnosis. Numerous efforts have been made to develop culturally specific interventions to both reduce risk of dementia, and to improve quality of life for people living with dementia.

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Longitudinal Cognitive and Physical Training Effectiveness in MCI, Based on the Experience of the Alzheimer’s Hellas Day Care Centre

Cited by 8 publications

References 75 publications

Are There Any Cognitive and Behavioral Changes Potentially Related to Quarantine Due to the COVID-19 Pandemic in People with Mild Cognitive Impairment and AD Dementia? A Longitudinal Study

Are There Any Cognitive and Behavioral Changes Potentially Related to Quarantine Due to the COVID-19 Pandemic in People with Mild Cognitive Impairment and AD Dementia? A Longitudinal Study

A Novel Method of Teaching English to People with Mild Cognitive Impairment Using Songs: A Randomized Controlled Trial Protocol

Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium

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