Longitudinal changes in iron homeostasis in human experimental and clinical malaria
Stephen D. Woolley,
Matthew J. Grigg,
Louise Marquart
et al.
Abstract:BackgroundThe interaction between iron deficiency and malaria is incompletely understood. We evaluated longitudinal changes in iron homeostasis in volunteers enrolled in malaria volunteer infection studies (VIS) and in Malaysian patients with falciparum and vivax malaria.MethodsWe retrieved samples and associated data from 55 participants enrolled in malaria VIS, and 171 malaria patients and 30 healthy controls enrolled in clinical studies in Malaysia. Ferritin, hepcidin, erythropoietin, and soluble transferri… Show more
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