Longitudinal Changes in Health-Related Quality of Life Scores in Brazilian Incident Peritoneal Dialysis Patients (Brazpd): Socio-Economic Status Not a Barrier

Grincenkov, Fabiane Rossi dos Santos; Fernandes, Natália; Chaoubah, Alfredo; Fernandes, Neimar da Silva; Bastos, Kleyton de Andrade; Lopes, Antônio Alberto; Qureshi, Abdul Rashid; Finkelstein, Fredric O.; Pecoits‐Filho, Roberto; Divino-Filho, José Carolino; Bastos, Marcus Gomes

doi:10.3747/pdi.2012.00038

Cited by 14 publications

(8 citation statements)

References 28 publications

(46 reference statements)

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“…The BRAZPD data provide a substrate for exploratory analysis in order to expand the overall therapy knowledge and consequently improve the quality of care for PD patients.Evaluating HRQOL in the same dataset, Grincenkov et al [8] reported that family income and educational level, as predictors, do not have an impact on HRQOL and these findings support the fact that socioeconomic status should not be a barrier to the selection of PD as a treatment modality.…”

Section: Introductionsupporting

confidence: 59%

Impact of Baseline Health-Related Quality of Life Scores on Survival of Incident Patients on Peritoneal Dialysis: A Cohort Study

Grincenkov¹,

Fernandes²,

Pereira³

et al. 2015

Nephron

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Introduction: In an attempt to decrease mortality in patients with end-stage renal disease, an increase in the lifetime of these patients without much focus on health-related quality of life (HRQOL) was pursued for a long period of time. However, lately, an improvement in the quality of this extended lifetime has focused on both the physical as well as the social and emotional aspects, as these parameters may be associated with clinical outcomes in end-stage renal disease patients. Aim: To evaluate the impact of self-determined HRQOL at admission on survival of incident peritoneal dialysis (PD) patients. Patients and Methods: A total of 1,624 incident Brazilian PD patients participating in a multicenter prospective cohort study (BRAZPD) were evaluated. HRQOL was assessed using the SF-36, divided into mental and physical components. Cox proportional regression analysis was used to determine the influence ofHRQOL (mental and physical components) on mortality. Multivariate Cox proportional hazards analyses were used to adjust gradually for more potential explanatory variables: first for demographic variables, followed by additional adjustment for socioeconomic, clinical and laboratory variables. The significance level in all analyses was set at p < 0.05. All analyses were carried out with SPSS 17.0. Results: Incident PD patients presented with low HRQOL scores on admission to therapy. Even after correction for sociodemographic variables, comorbidities, PD modality and laboratory parameters, HRQOL (both the mental and the physical components) remained a predictor [HR: 0.97 (CI: 0.95-0.98); HR: 0.97 (CI: 0.96-0.99), respectively] of survival. Conclusion: On admission to therapy, patients presenting with low HRQOL scores for both the mental and the physical components were associated with a higher mortality. These results suggest that early and timely intervention measures to improve the QOL of these patients are important.

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Section: Introductionsupporting

confidence: 59%

Impact of Baseline Health-Related Quality of Life Scores on Survival of Incident Patients on Peritoneal Dialysis: A Cohort Study

Grincenkov¹,

Fernandes²,

Pereira³

et al. 2015

Nephron

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“…Peritoneal dialysis has been used for more than 30 years in Brazil; however, publications on the epidemiology and clinical experience in this type of treatment, as well as the number of patients who opt for it, are incipient ( 3 - 4 ) .…”

Section: Introductionmentioning

confidence: 99%

Health-related quality of life as a predictor of mortality in patients on peritoneal dialysis

Oliveira

Kusumota

Haas

et al. 2016

Rev. Latino-Am. Enfermagem

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Objective:to characterize deaths that occurred, and the association between socio-demographic, clinical, laboratory variables and health-related quality of life and the outcome of death in patients on peritoneal dialysis, over a two year period after an initial assessment. Method:observational, prospective population study with 82 patients on peritoneal dialysis. The instruments used for the first stage of data collection were the mini-mental state examination, a sociodemographic, economic, clinical and laboratory questionnaire and the Kidney Disease and Quality of Life-Short Form. After two years, data for characterization and occurrence of death in the period were collected. The relative risk of death outcome was calculated through statistical analysis; the risk of death was estimated by the survival Kaplan-Meier curve, and determined predictors of death by the Cox Proportional Hazards Model. Results:of the 82 original participants, 23 had as an outcome death within two years. The increased risk for the outcome of death was associated with a lower mean score of health-related quality of life in the physical functioning domain. Conclusion:the worst health-related quality of life in the physical functioning domain, could be considered a predictor of death.

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“…No Brasil, há escassez de estudos transversais que avaliem a QVRS de pacientes em DP (ARENAS et al, 2009;BOHLKE et al, 2008;GRINCENKOV et al, 2011;OLIVEIRA et al, 2012) e esta escassez é ainda maior, ao se referir a estudos do tipo longitudinal. Foi encontrado um artigo elaborado com dados do estudo multicêntrico entitulado Brazilian Peritoneal Dialysis Multicenter Study (BRAZPD), no qual a QVRS dos pacientes em DP foi avaliada por meio de instrumento genérico SF-36 em seguimento de 12 meses (GRINCENKOV et al, 2013), enquanto o único que avaliou a QVRS de pacientes em DP e em HD por meio de instrumento genérico e específico, o Kidney Disease and Quality of Life Short Form (KDQOL-SF TM ), seguiu os pacientes também por 12 meses (ABREU et al, 2011). Há, portanto, carência de estudos brasileiros sobre as mudanças que podem ocorrer na QVRS dos pacientes em DP, com o passar do tempo.…”

Section: Lista De Figurasunclassified

“…A DP teve início no Brasil há mais de 30 anos, porém as publicações sobre a epidemiologia e experiência clínica neste tipo de TRS, bem como o número de pacientes que optam por ela ainda são pequenos (FERNANDES et al, 2008;GRINCENKOV et al, 2013;RIELLA;LOCATELLI, 2007).…”

Section: A Doença Renal Crônica E a Diálise Peritonealunclassified

“…O número restrito de pacientes que completaram o seguimento também foi observado em outros estudos. Os estudos que avaliaram a QVRS em pacientes em tratamento por DP em mais de uma medida, ainda que sejam poucos, também tiveram redução significativa na população acompanhada entre a primeira e as medidas subsequentes (BAKEWELL, HIGGINS, EDMUNDS, 2002;GRINCENKOV et al 2013;TERMORSHUIZEN et al 2003;WU et al, 2004 Diante disso, destaca-se que as discussões sobre o estudo de seguimento da QVRS de pacientes em DP e suas relações com as variáveis de interesse serão apresentadas ao longo do texto, considerando a produção científica disponível.…”

Section: Dpacunclassified

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Diálise peritoneal e qualidade de vida relacionada à saúde: um estudo longitudinal

Oliveira¹

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Ao final de mais uma etapa, alguns agradecimentos são essenciais, pois sem a contribuição dessas pessoas não teria alcançado este objetivo. A Deus, por ser o maior responsável por esta conquista, por me guiar, me iluminar e me dar forças para continuar, mesmo diante das dificuldades. À Profa. Dra. Luciana Kusumota, por ter me aceitado mais uma vez como aluna, pelos valiosos ensinamentos acadêmicos e de vida, pela paciência, dedicação e amizade. Luciana, qualquer agradecimento seria muito pouco diante de tudo aquilo que tem feito por mim durante todos esses anos. Minha querida orientadora, a você minha eterna amizade e gratidão. À Profa. Dra. Rosana Aparecida Spadoti Dantas, pela disponibilidade e pelas colaborações no exame de qualificação. Ao Prof. Dr. José Abrão Cardeal da Costa, pela colaboração no exame de qualificação e generosidade em compartilhar aquilo que sabe. À Profa. Dra. Sueli Marques, pelo carinho, incentivo e pela paciência em compartilhar sua sala também comigo, em muitos momentos. A todos os professores que participaram da minha formação em especial à Profa. Dra. Rita C. H. M. Ribeiro e Profa. Dra. Claudia Cesarino, referências em minha vida profissional e pessoal, pelo carinho e apoio constantes, mesmo depois de tantos anos de formada.

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Longitudinal Changes in Health-Related Quality of Life Scores in Brazilian Incident Peritoneal Dialysis Patients (Brazpd): Socio-Economic Status Not a Barrier

Cited by 14 publications

References 28 publications

Impact of Baseline Health-Related Quality of Life Scores on Survival of Incident Patients on Peritoneal Dialysis: A Cohort Study

Impact of Baseline Health-Related Quality of Life Scores on Survival of Incident Patients on Peritoneal Dialysis: A Cohort Study

Health-related quality of life as a predictor of mortality in patients on peritoneal dialysis

Diálise peritoneal e qualidade de vida relacionada à saúde: um estudo longitudinal

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