Abstract:Introduction: Endocrinopathies are common in regularly transfused patients with β-thalassemia major (TM). Damage may start in childhood with the incidence of overt endocrine complications increasing with advancing age, making it essential to introduce appropriate intervention promptly to prevent the development of later morbidity. Iron overload has been consistently linked with the development of endocrine disease in TM. However, data on the role of iron chelation therapy for the prevention or management of en… Show more
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