Longitudinal calcium intake is negatively related to children’s body fat indexes

Skinner, Jean D.; Bounds, Wendy; Carruth, Betty Ruth; Ziegler, Paula

doi:10.1016/j.jada.2003.09.018

Cited by 191 publications

(153 citation statements)

References 28 publications

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“…Some studies have suggested an intracellular role of calcium or other components of dairy products in body weight regulation, 26 a hypothesis supported by several observational and experimental studies. [27][28][29] Our findings contribute to support this hypothesis.…”

Section: Discussionsupporting

confidence: 80%

Adherence to a Mediterranean dietary pattern and weight gain in a follow-up study: the SUN cohort

et al. 2005

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Introduction: The promotion of Mediterranean Diets has generated some doubts, because of the concern that its high fat content might lead to the development of obesity. Methods: Longitudinal analysis of 6319 participants in the SUN cohort study. We used a validated semiquantitative food frequency questionnaire (136 items). Baseline adherence to a Mediterranean dietary pattern (MDP) was assessed using a score (score_1) including vegetables, fruits, cereals, nuts, pulses, fish, olive oil and moderate consumption of red wine (positively weighted), whereas meat and dairy products were negatively weighted. We assessed the association between the overall baseline adherence to the MDP (score_1) and subsequent weight change after 28 months of follow-up. We also built another score (score_2) to assess changes in diet during follow-up and appraised the association between the joint exposure to both scores and weight change during follow-up. Results: Participants in the first quartile of score_1 (lowest baseline adherence to MDP) showed a higher weight gain ( þ 0.73 kg) than those in the top quartile ( þ 0.45 kg). The results indicated an inverse dose-response relationship (P for trend ¼ 0.016). A similar inverse association was apparent when we used change in adherence to the MDP (score_2). However, both inverse associations did not remain statistically significant after adjusting for relevant confounders. Consumption of dairy products was inversely associated with weight gain. Conclusions: Although participants increased their average weight during the follow-up period, weight increments were smaller among those with a higher adherence to an 'a priori' defined MDP. Results did not remain statistically significant after multivariate adjustment.

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Section: Discussionsupporting

confidence: 80%

Adherence to a Mediterranean dietary pattern and weight gain in a follow-up study: the SUN cohort

et al. 2005

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“…Previous studies have confirmed a positive association between the LP allele and BMI (Kettunen et al 2010;Corella et al 2011;Almon et al 2012); however, in children, association studies have shown increased dairy consumption in carriers of the LP allele but no marked association with BMI levels (Almon et al 2010). Additionally, others have described a negative association between dairy intake, regardless of fat content, and BMI (Slyper and Huang 2009), further implicating dairy products as both pro and anti-obesogenic (Remesar et al 1999;Berkey et al 2005;Skinner et al 2003;Lehtimäki et al 2006). In an attempt to further understand the complex relationships among lactose intake (rather than dairy alone), genetic variation and body composition, we evaluated if individuals with the lactase persistence (LP) allele of the LCT SNP (rs4988235) would exhibit a greater degree of adiposity, potentially mediated by lactose consumption.…”

Section: Introductionmentioning

confidence: 99%

Associations of the lactase persistence allele and lactose intake with body composition among multiethnic children

et al. 2013

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Childhood obesity is a worldwide health concern with a multifaceted and sometimes confounding etiology. Dairy products have been implicated as both proand anti-obesogenic, perhaps due to the confounding relationship between dairy, lactose consumption, and potential genetic predisposition. We aimed to understand how lactase persistence influenced obesity-related traits by observing the relationships among lactose consumption, a single nucleotide polymorphism (SNP) near the lactase (LCT) gene and body composition parameters in a sample of multiethnic children (n = 296, 7-12 years old). We hypothesized that individuals with the lactase persistence (LP) allele of the LCT SNP (rs4988235) would exhibit a greater degree of adiposity and that this relationship would be mediated by lactose consumption. Body composition variables were measured using dual X-ray absorptiometry and a registered dietitian assessed dietary intake of lactose. Statistical models were adjusted for sex, age, pubertal stage, ethnic group, genetic admixture, socio-economic status, and total energy intake. Our findings indicate a positive, significant association between the LP allele and body mass index (p = 0.034), fat mass index (FMI) (p = 0.043), and waist circumference (p = 0.008), with associations being stronger in males than in females. Our results also reveal that lactose consumption is positively and nearly significantly associated with FMI.

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“…5,6 Overall, each 300 mg increment in regular calcium intake is associated with approximately 1 kg less body fat in children, and 2.5-3.0 kg lower body weight in adults. 2 Davies et al 7 also reported a negative association between calcium intake and BMI in women; in their study of five separated studies on calcium intake for osteoporosis in which weight was also recorded, an increment in the calcium intake of 100 mg/day led to a 0.82 kg weight decrease.…”

Section: Introductionmentioning

confidence: 99%

Milk intake is inversely related to obesity in men and in young women: data from the Portuguese Health Interview Survey 1998–1999

Marques‐Vidal

Gonçalves

Dias³

2005

Int J Obes

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Objective: To assess the relationships between milk intake and body mass index (BMI) in a representative sample of the mainland Portuguese population. Design: Cross-sectional study. Setting: National Health Interview Survey 1998-1999. Average daily milk intake was calculated by a frequency questionnaire that also assessed the average volume of one serving. BMI was derived from the subject's reported height and weight. Subjects: A total of 17 771 men and 19 742 women aged X18 y. Results: In men, milk intake was inversely related to BMI (r ¼ À0.10, Po0.001), whereas the relationship in women was weaker (r ¼ À0.06, Po0.001). In men, prevalence of milk consumers was lower in obese (62%) and in overweight (68%) than in normal weight subjects (71%, Po0.001). After adjusting for age, region, physical activity, smoking, number of meals and educational level, milk intake decreased with increasing BMI (adjusted mean7s.e.: 28075, 26675 and 24677 ml/day for normal, overweight and obese subjects, respectively, Po0.001), even after excluding subjects who did not consume milk (36875, 35376 and 34678 ml/day, Po0.02). In women, prevalence of milk consumers was lower in obese (71%) and in overweight (72%) than in normal weight subjects (76%, Po0.001). In women younger than 55 y, milk intake decreased with increased BMI categories (29179, 271710 and 269711 ml/day for normal, overweight and obese subjects, respectively, Po0.001), whereas no relationship was found in the older group. Conclusions: Increased calcium intake is slightly but significantly negatively related with BMI in men and premenopausal women. The lack of relationship in older women might be due to the hormonal status, but awaits further investigation.

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Longitudinal calcium intake is negatively related to children’s body fat indexes

Cited by 191 publications

References 28 publications

Adherence to a Mediterranean dietary pattern and weight gain in a follow-up study: the SUN cohort

Adherence to a Mediterranean dietary pattern and weight gain in a follow-up study: the SUN cohort

Associations of the lactase persistence allele and lactose intake with body composition among multiethnic children

Milk intake is inversely related to obesity in men and in young women: data from the Portuguese Health Interview Survey 1998–1999

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