Longitudinal associations between dietary inflammatory index and musculoskeletal health in community-dwelling older adults

Cervo, Mavil May; Shivappa, Nitin; Hébert, James R.; Oddy, Wendy H.; Winzenberg, Tania; Balogun, Saliu; Wu, Feitong; Ebeling, Peter R.; Aitken, Dawn; Jones, Graeme; Scott, David

doi:10.1016/j.clnu.2019.02.031

Cited by 62 publications

(89 citation statements)

References 43 publications

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“…Cervo et al, examined prospective associations between DII scores and bone health, sarcopenia-related outcomes, falls risk and incident fractures in Australian older adults (n = 1099 aged 50–79 at baseline, with 5 year (n = 768) and 10 year (n = 566) follow-up). They report that among men a more pro-inflammatory diet was associated with lower hip and lumbar spine BMD and greater risk of fractures and falls over 10 years, whereas among women, a more pro-inflammatory diet was associated with greater lower limb muscle quality and reduced fracture risk [282].…”

Section: DII and Musculoskeletal Healthmentioning

confidence: 99%

Dietary Inflammatory Index and Non-Communicable Disease Risk: A Narrative Review

et al. 2019

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There are over 1,000,000 publications on diet and health and over 480,000 references on inflammation in the National Library of Medicine database. In addition, there have now been over 30,000 peer-reviewed articles published on the relationship between diet, inflammation, and health outcomes. Based on this voluminous literature, it is now recognized that low-grade, chronic systemic inflammation is associated with most non-communicable diseases (NCDs), including diabetes, obesity, cardiovascular disease, cancers, respiratory and musculoskeletal disorders, as well as impaired neurodevelopment and adverse mental health outcomes. Dietary components modulate inflammatory status. In recent years, the Dietary Inflammatory Index (DII®), a literature-derived dietary index, was developed to characterize the inflammatory potential of habitual diet. Subsequently, a large and rapidly growing body of research investigating associations between dietary inflammatory potential, determined by the DII, and risk of a wide range of NCDs has emerged. In this narrative review, we examine the current state of the science regarding relationships between the DII and cancer, cardiometabolic, respiratory and musculoskeletal diseases, neurodevelopment, and adverse mental health outcomes. We synthesize the findings from recent studies, discuss potential underlying mechanisms, and look to the future regarding novel applications of the adult and children’s DII (C-DII) scores and new avenues of investigation in this field of nutritional research.

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Section: DII and Musculoskeletal Healthmentioning

confidence: 99%

Dietary Inflammatory Index and Non-Communicable Disease Risk: A Narrative Review

et al. 2019

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“…The DII has been shown to be associated with a number of health outcomes including cancer, CVD, adverse mental health and musculoskeletal disorders [15][16][17][18][19]. However, the association between DII and MetS has been inconsistent across studies.…”

Section: Introductionmentioning

confidence: 99%

Proinflammatory Dietary Intake is Associated with Increased Risk of Metabolic Syndrome and Its Components: Results from the Population-Based Prospective Study

et al. 2020

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Metabolic syndrome (MetS) is a major public health challenge throughout the world, although studies on its association with the inflammatory potential of diet are inconsistent. The aim of this prospective study was to assess the association between the Dietary Inflammatory Index (DII®) and the risk of MetS and its components in a Korean population. Data from 157,812 Korean adults (mean age 52.8 years; 53,304 men and 104,508 women with mean follow-up of 7.4 years) collected by members of the Korean Genome and Epidemiology Study form the basis for this report. DII scores were calculated based on Semi-Quantitative Food-Frequency Questionnaire data. Multivariable-adjusted Cox proportional hazard models were used to estimate the association between DII scores and MetS. In women, higher DII scores (pro-inflammatory diet) increased the risk of MetS (hazard ratio [HR]quintile5 v. 1 1.43; 95% confidence interval (CI) 1.21–1.69; p for trend ≤ 0.0001) and its five components. A positive association was observed for postmenopausal women, with a 50% higher risk of developing MetS (HRquintile5 v. 1 1.50; 95% CI 1.23–1.83; p for trend = 0.0008) after fully adjusting for potential confounders. Irrespective of the menopausal status of women, higher DII (=Q5) scores were positively associated with all 5 components of MetS (p < 0.05). In men, higher DII scores significantly increased the risk of low HDL cholesterol [HR]quintile5 v. 1 1.59 (1.27–1.99); p for trend = 0.0001], elevated waist circumferences [HR]quintile5 v. 1 1.28 (1.08–1.52); p for trend = 0.01], and high blood pressure [HR]quintile5 v. 1 1.17 (1.03–1.32); p for trend = 0.05]. These results indicate that diet with pro-inflammatory potential, as represented by higher DII scores, is prospectively associated with increased risk of MetS, and the relationship is stronger in women than in men.

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“…They did not reach any signi cant association between DII and handgrip strength [29]. A prospective population-based study in Australia with 1099 men and women aged 50-79 years old revealed that higher DII score was not associated with a lower appendicular lean mass and handgrip strength after controlling for covariates [6]. It seems that additional information are required to shed light on the link between dietary in ammatory index and individual components of sarcopenia, given that there is a possible association between in ammation and sarcopenia, as indicated in a recent meta-analysis [5].…”

Section: Discussionmentioning

confidence: 99%

“…This dietary index has linked with several cancers, metabolic diseases, and fractures [14][15][16]. Two longitudinal cohort studies have also shown that higher DII scores were associated with a higher incidence of frailty [17] and decreased appendicular lean mass [6]. Given the limited studies on the association of in ammatory potential of the diet with muscle health, along with the great differences in dietary intakes, lifestyle factors and body composition of people in the Middle East with those in Western countries, this cross-sectional study aimed to investigate the relationship between DII with sarcopenia in an Iranian population.…”

Section: Introductionmentioning

confidence: 98%

“…In ammatory cytokines lead to rapid muscle wasting, eventually stimulate protein catabolism and suppress muscle synthesis [5]. Dietary factors have been shown to contribute to in ammation [6]. High intakes of fruits and vegetables [7], and also speci c nutrients such as ber [8], omega-3 fatty acids [9], vitamin E [10], and vitamin C [11] were associated with lower concentrations of circulating in ammatory markers.…”

Section: Introductionmentioning

confidence: 99%

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Inflammatory Potential of the Diet and Risk of Sarcopenia and its Components

Bagheri

Soltani

Hashemi

et al. 2020

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Background: Despite huge evidence on the link between dietary inflammatory index (DII) and several chronic conditions, limited data are available about the association of DII and sarcopenia. This study aimed to examine the relationship between inflammatory potential of the diet (as measured by DII) and sarcopenia and its components among community-dwelling elderly population.Methods: This population-based cross-sectional study was performed in 2011 among 300 elderly people (150 men and 150 women) aged ≥55 years, who were selected using cluster random sampling method. Dietary assessment was done using a pre-tested food frequency questionnaire. Energy-adjusted DII was calculated based on earlier studies. Sarcopenia and its components were determined based on the European Working Group on Sarcopenia (EWGSOP) definition.Results: Mean age of study participants was 66.7 ± 7.7 y. Subjects in the highest tertile of DII were more likely to be older (P=0.02). The prevalence of sarcopenia (P=0.016) and abnormal muscle mass (P=0.041) was significantly higher among subjects in the top tertile compared with those in the bottom tertile of DII. After adjustment for potential confounders, those with the highest DII were 2.18 times (95% CI: 1.01-4.74) more likely to have sarcopenia than those with the lowest DII. With regard to components of sarcopenia, subjects in the top tertile of DII had not significantly greater odds of abnormal muscle mass (OR: 1.38; 95% CI: 0.72-2.63), abnormal handgrip strength (OR: 0.97; 95% CI: 0.49-1.89), and abnormal gait speed (OR: 1.61; 95% CI: 0.84-3.08) than those in the bottom tertile.Conclusions: In conclusion, a diet with more pro-inflammatory potential was associated with a greater odd of sarcopenia. Further studies are required to confirm these findings.

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Longitudinal associations between dietary inflammatory index and musculoskeletal health in community-dwelling older adults

Cited by 62 publications

References 43 publications

Dietary Inflammatory Index and Non-Communicable Disease Risk: A Narrative Review

Dietary Inflammatory Index and Non-Communicable Disease Risk: A Narrative Review

Proinflammatory Dietary Intake is Associated with Increased Risk of Metabolic Syndrome and Its Components: Results from the Population-Based Prospective Study

Inflammatory Potential of the Diet and Risk of Sarcopenia and its Components

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