Longitudinal Assessment of Calcium and Magnesium Levels in Women with Preeclampsia

Wadhwani, Nisha; Dangat, Kamini; Randhir, Karuna; Poddar, Anupam; Joshi, Prachi; Pisal, Hemlata; Kadam, Vrushali; Bakshi, Ravleen Kaur; Chandhiok, Nomita; Lalwani, Sanjay; Mehendale, Savita; Wagh, Girija; Gupte, Suraj; Sachdev, Harshpal Singh; Fall, Caroline; Joshi, Sadhana

doi:10.1007/s12011-022-03440-y

Cited by 4 publications

(2 citation statements)

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“…Women with PE had higher maternal weight and BMI compared to non‐PE women at all time points and has been reported by us recently 28 . Similarly, at all the time points, the systolic and diastolic blood pressure was also higher in women with PE ( p < .01 for all).…”

Section: Resultssupporting

confidence: 85%

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Longitudinal profile of high‐sensitivity C‐reactive protein in women with pre‐eclampsia

Dangat

Wadhwani

Randhir

et al. 2023

American J Rep Immunol

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Problem: C-reactive protein (CRP) is a marker for inflammation and its role as a possible biomarker for an early prediction of pre-eclampsia (PE) is unclear. The present study investigates the levels of high-sensitivity CRP (hs-CRP) longitudinally across pregnancy in women with PE and compares them to women without PE (non-PE). Method of Study: A total of 324 pregnant women [216 non-PE and 108 PE women]were included in this study. Maternal blood was taken at four different intervals (V1 = 11-14 weeks, V2 = 18-22 weeks, V3 = 26-28 weeks, and V4 = at delivery).Results: Maternal serum hs-CRP levels were higher at V1, V2, and V3 (p < .05 for all) in the PE group compared to the non-PE group. The hs-CRP levels were associated with maternal blood pressure throughout pregnancy. Maternal hs-CRP levels did not differ among early and late onset PE. Higher maternal hs-CRP levels were associated with the increased risk of PE in unadjusted model in early pregnancy. However, there was no significance after adjusting for confounding factors. Conclusions:Our findings suggest although the levels of hs-CRP were higher in PE in early pregnancy, they are not associated with an increased risk of PE.

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Section: Resultssupporting

confidence: 85%

“…The mean gestational age at which PE was clinically diagnosed was 34.3 (SD = 4.94, range = 24.0–40.6) weeks. As compared to non‐PE group, the gestational age at birth ( p < .01) and baby weight were both lower ( p < .05) in PE group 28 …”

Section: Resultsmentioning

confidence: 81%