Longitudinal analysis of Flower-dependent cell competition fitness markers inDrosophila melanogaster
Mariana Marques-Reis,
Barbara Hauert,
Eduardo Moreno
Abstract:Cell competition is a conserved phenomenon spanning from arthropods to humans. It involves the elimination of viable yet suboptimal "loser" cells when juxtaposed with their fitter "winner" counterparts. This process has received increased attention for its implications in cancer initiation and progression, neurodegeneration, and ageing. This study investigates the presence of the loser fitness fingerprint Flower LoseB (Fwe LB) and the fitness checkpoint Azot in the optic lobes over a period of 28 days. Notably… Show more
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