Long-term yogic intervention decreases serum interleukins IL-10 and IL-1β and improves cancer-related fatigue and functional scale during radiotherapy/chemotherapy in breast cancer patients: a randomized control study

Jain, Mayank; Mishra, Archana; Yadav, Vishnu; Shyam, Hari; Kumar, Sanjay; Ramakant, Pooja

doi:10.1007/s00520-022-07487-4

Cited by 8 publications

(3 citation statements)

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“…The majority of the patients in each group were illiterate, 69% in the control group and 54% in the yoga group. More details of the clinical characteristics, socioeconomic status and demographics of the study population were published in a previous article [ 16 ].…”

Section: Resultsmentioning

confidence: 99%

“…The details of these yogic asanas are: Sukshma Vyayama (loosening exercises) (seven minutes), Tadasana (mountain pose) (two minutes), Kati Chakrasana (lateral arc pose) (two minutes), Padadhirasana (standing forward bend) (three minutes), Tiryaka Tadasana (swaying palm tree pose) (two minutes), Hridaya Mudra (heart gesture) (two minutes), Gomukhasana (cow face pose) (three minutes), Nadi Shodhana Pranayama (alternate-nostril breath) (three minutes), Bhramari Pranayama (bee breath) (two minutes), Ujjayi Pranayama (Ocean Breath), and Shavasana (corpse) (five minutes). Humming in meditative posture: meditation, Om chanting (10 minutes), or Yoga Nidra (alternate days for 30 min) [ 16 ].…”

Section: Methodsmentioning

confidence: 99%

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Long-Term Yogic Intervention Improves Symptomatic Scale and Quality of Life by Reducing Inflammatory Cytokines and Oxidative Stress in Breast Cancer Patients Undergoing Chemotherapy and/or Radiotherapy: A Randomized Control Study

Jain¹,

Mishra²,

Yadav³

et al. 2023

Cureus

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Introduction: Inflammation has been associated with tumor proliferation and metastasis in breast cancer. Yoga is an ancient therapy that helps in reducing inflammation and improves the patient's quality of life (QoL) and fatigue. In the current study, we investigated the effects of long-term yogic intervention at different time points on the level of inflammatory cytokines and oxidative stress, along with the symptomatic scale and QoL in stage II/III breast cancer patients.Methods: Ninety-six stage II/III breast cancer patients receiving chemotherapy and/or radiotherapy were enrolled and divided into two groups, non-yoga (Group I) and yoga (Group II). Participants in Group II practiced yoga five days per week for 48 weeks. The European Organisation for Research and Treatment of Cancer quality of life questionnaire (EORTC-QLQ30) was used to measure the QoL and symptomatic scale. Serum levels of pro-inflammatory cytokines, tumor necrosis factor-alpha (TNF-α), interferon-γ (IFN-γ) and granulocyte macrophage colony-stimulating factor (GM-CSF), and oxidative stress markers, superoxide dismutase (SOD), catalase (CAT), malondialdehyde (MDA), and nitric oxide (NO) were measured at baseline, 16, 32, and 48 weeks in both groups.Results: Yoga significantly (p<0.05) reduced the level of IFN-γ, TNF-α, and MDA and improved QoL (p<0.001) and symptomatic scale (p<0.05) in Group II patients compared to Group I. NO was upregulated in Group I whereas in Group II, it was neither decreased nor increased.Conclusion: These findings suggest that yoga may reduce levels of inflammatory cytokines and improve QoL and symptomatic scale in breast cancer patients receiving chemotherapy and/or radiotherapy. Yoga can be an important additional therapy during cancer treatments to cope with treatment side effects including fatigue, depression, and immunological profile, which directly affects the patient's quality of life.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Long-Term Yogic Intervention Improves Symptomatic Scale and Quality of Life by Reducing Inflammatory Cytokines and Oxidative Stress in Breast Cancer Patients Undergoing Chemotherapy and/or Radiotherapy: A Randomized Control Study

Jain¹,

Mishra²,

Yadav³

et al. 2023

Cureus

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“…Meditation, Atemtherapie (Pranayama), MBSR (Mindfulness Based Stress Reduction), Yoga und andere geistig-spirituelle Praktiken können die Lebensqualität steigern, den Umgang mit schwierigen Gefühlen ermöglichen, Stress reduzieren und eine positive Wirkung auf die psychische Verfassung haben und somit die Bewältigung der Krankheit verbessern 46 47 . Therapien wie MBSR sind nicht in den klassischen Ayurveda-Texten beschrieben, sondern haben jüngere Entwicklungslinien, dennoch speisen sie sich inhaltlich stark aus indischen Wissenstraditionen.…”

Section: Therapieansätze Der Ayurveda-medizinunclassified

Ayurveda bei onkologischen Erkrankungen

Keßler,

K. Schiele

2024

Zeitschrift für Komplementärmedizin

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SummaryIn der Onkologie kann Ayurveda eine komplementärmedizinische Rolle spielen. Ayurveda betrachtet den Körper als selbstregulierendes Milieu, gesteuert durch funktionelle Prinzipien (v. a. Dosha, Agni) und physiologische Strukturen (v. a. Dhatu, Mala, Srotas). Krebserkrankungen werden im Ayurveda als Systemerkrankungen verstanden. So sind in die Ätiopathogenese onkologischer Erkrankungen zumeist alle 3 Dosha involviert.Die supportive Ayurveda-Behandlung von Krebs kann je nach vorliegender Fragestellung Ursachenvermeidung oder Prävention, spezielle körperliche Reinigungsverfahren (Pancakarma), Stoffwechselkorrekturmaßnahmen, Immunmodulation, Geweberegeneration (Rasayana) sowie psychomentale Stärkung durch Meditation, therapeutisches Yoga und Manualtherapie umfassen. Die Grenzen der komplementäronkologischen Ayurveda-Behandlung in Deutschland liegen vor allem in der Verfügbarkeit seriöser Versorgungsangebote und -sicherer Phytotherapeutika sowie in dem finanziellen Aufwand, da Krankenversicherungsträger die Kosten dieser Therapien in der Regel nicht übernehmen. Wissenschaftliche Evidenz entsprechend EbM ist noch sehr limitiert, jedoch existiert ein breites, über mehrere Jahrtausende systematisiertes, erfahrungsmedizinisches Wissen. In der Praxis zeigt sich, dass Ayurveda eine sinnvolle Ergänzung zur konventionellen Krebsbehandlung sein kann, vor allem wenn es darum geht, die onkospezifische Lebensqualität zu verbessern und Nebenwirkungen zu verringern.

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