Long-Term Weight Loss Outcome of Laparoscopic Sleeve Gastrectomy Predicted by the Percentage of Excess Weight Loss at 6 Months in Chinese Patients with Body Mass Index ≥ 32.5 Kg/m2

Abstract

Purpose To evaluate the predictive effect of the initial weight loss on the long-term weight loss in Chinese patients with a body mass index (BMI) ≥ 32.5 kg/m 2 who underwent LSG. Patients and Methods The follow-up was completed via phone or WeChat for outpatients and at the hospital for inpatients. We evaluated the BMI, percentage of excess weight loss (%EWL), and type 2 diabetes mellitus, hypertension, and hyperlipidemia statuses. Linear and logistic regression analyses were performed on the relationship between the initial and long-term weight loss. The optimal cut-off value was determined by receiver operating characteristic (ROC) curve analysis. Results We enrolled 307 patients, with a median preoperative BMI of 39.68 (35.68, 45.47) kg/m 2 . %EWL ≥ 50% was regarded as successful weight loss, and 76.55% of the patients lost their weight successfully. (Reviewer #1, comment #4) %EWL at 6 months and 5 years were positively correlated ( P < 0.001). Further, the following linear equation could express the relationship: (%EWL 5 years = 29.193 + 0.526 × %EWL 6 months ). %EWL ≥ 58.57% at 6 months was the best predictor of successful weight loss at 5 years after LSG (Reviewer #1, comment #5) (sensitivity, 73.62%; specificity, 73.61%; AUC value, 0.780). Internal verification of the prediction model revealed satisfactory results in terms of discrimination and calibration. Conclusion In Chinese patients with BMI ≥ 32.5 kg/m 2 who underwent LSG, %EWL at 6 months and 5 years were correlated. %EWL ≥ 58.57% at 6 months was a predictor of successful long-term weight loss.

Fat mass index predicts the effect of weight loss and quality of life early after laparoscopic sleeve gastrectomy

“…[29]. The %EWL at 6 months after LSG is an independent factor that in uences long-term weight loss effect after MBS [30]. Therefore, this study innovatively de ned early weight loss effect as achieving the ideal BMI (%EWL ≥ 100) at 6 months postoperatively.…”