Long-term vitamin status and dietary intake of healthy elderly subjects

Bates, Christopher J.; Rutishauser, I. H. E.; Black, A.; Paul, Alison; Mandal, Anandadeep; Patnaik, B.K.

doi:10.1079/bjn19790088

Cited by 52 publications

(16 citation statements)

References 30 publications

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“…Furthermore, plasma vitamin C concentration has been shown to be highly correlated with buffy-coat (leukocyte) vitamin C concentration and was an equally good index of long-term status over 18 months [28]. In addition, in the same study, a single measure of vitamin C concentration ranked individuals as well as the mean of six measures taken over the 18-month period and plasma vitamin C concentration correlated well with the longterm intake of vitamin C in that study [28].…”

Section: Discussionmentioning

confidence: 99%

Interaction of vitamin C with the relation between smoking and obstructive airways disease in EPIC Norfolk

2000

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Previous studies have reported an association between plasma vitamin C levels and respiratory function, but have not examined the role of vitamin C as an effect modifier of the relation between cigarette smoking and obstructive airways disease (OAD).This question was investigated in a cross-sectional analysis of a population-based study of 3,714 males and 4,256 females aged 45±74 yrs. Undiagnosed OAD was defined as a forced expiratory volume in one second (FEV1) of <80% of the predicted value and FEV1/forced vital capacity of <70% without self-reported OAD.An increase of 20 mmol . L -1 (or 1 SD) in plasma vitamin C concentration was associated with a 13% reduction in the risk of having OAD (adjusted odds ratio (OR) (95% confidence interval) 0.87 (0.77±0.98)). The OR for current smokers relative to never smokers within the lowest quintile of plasma vitamin C concentration was 5.93 (3.03±11.61). The risk in the upper four quintiles was 2.84 (1.92±4.19). Within the lowest quintile of plasma vitamin C concentration, the risk in former smokers was strongly related to the time since quitting (interaction significant, p=0.001).These findings support a protective role for vitamin C against the risk of obstructive airways disease and support the hypothesis that vitamin C may be an effect modifier for the adverse effects of smoking on the risk of obstructive airways disease.

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Section: Discussionmentioning

confidence: 99%

Interaction of vitamin C with the relation between smoking and obstructive airways disease in EPIC Norfolk

2000

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“…In conclusion, the National Diet and Nutrition Survey of people aged 65 years and over has added to the findings of earlier British surveys and studies of older people (Department of Social Security, 1972, 1979;Bates et al 1979Bates et al , 1980Rutishauser et al 1979;Department of Health, 1992). People aged 65 years or over living in mainland Britain had micronutrient intakes which were, with the possible exception of four nutrients, generally within the range considered adequate by comparison with the dietary reference values (Department of Health, 1991).…”

Section: Biochemical Status Indicesmentioning

confidence: 99%

Micronutrients: highlights and research challenges from the 1994–5 National Diet and Nutrition Survey of people aged 65 years and over

et al. 1999

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The aims of the National Diet and Nutrition Survey series are summarized, and the new National Diet and Nutrition Survey of people aged 65 years and over is explored, with particular emphasis on micronutrient intakes and status indices. Mean nutrient intakes were generally satisfactory for most micronutrients, but intakes of vitamin D, Mg, K and Cu were low. Intakes of vitamin D were far below the reference nutrient intake for people aged 65 years and over, and there was also biochemical evidence of vitamin D deficiency, for 8 % of free-living and 37 % of institution participants, attributed partly to limited exposure to sunlight. A substantial proportion of people living in institutions had inadequate biochemical status indices, notably for vitamin C, Fe and folate. Relationships between intake and status were close for vitamins. Mineral intakes did not correlate well with currently used status indices. Some intakes and indices, especially those of vitamin C, carotenoids, Na and K, were strongly correlated with socio-economic status and with north-south gradients in Britain. Future research challenges should address the functional and health significance of low intakes and sub-optimal biochemical indices for certain micronutrients, especially for people living in institutions; the shortcomings of mineral status indices especially as indicators of mineral intake; the social and geographical inequalities of micronutrient intakes and status, and why micronutrient status deteriorates with increasing age. The answers to these questions will help to define the characteristics of nutritional risk for older people in Britain, and to clarify future needs for education and intervention. Micronutrients: National Diet and Nutrition Survey: ElderlyThe purpose of the present paper is to draw attention to the British Government's National Diet and Nutrition Survey of people aged 65 years and over, and the reports derived from it Steele et al. 1998). It also considers some of the problems of interpretation and research challenges of this large dataset in order to encourage other researchers to continue this investigation. The primary data from the survey will be lodged with the

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“…It may be argued that the use o f a single measure to determine vitamin C status may be subject to misclassification error. However, it has been demonstrated that although higher dietary vitamin C intakes are associated with more intra-individual variation in serum levels than low intake levels, a single measure is a good indicator of chronically low levels of vitamin C intake (Jacob, Skala & Omaye, 1987;Bates, Rutishauser, Black et al, 1979).…”

Section: Discussionmentioning

confidence: 99%