Long-term Visual Function in Acute Posterior Multifocal Placoid Pigment Epitheliopathy

Wolf, Mitchell D.; Alward, Wallace L.M.; Folk, James C.

doi:10.1001/archopht.1991.01080060064025

Cited by 47 publications

(32 citation statements)

References 11 publications

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“…Progressive choroidal atrophy has been reported by Damato et al [17], who noted that some subjects in their long-term follow-up of APMPPE cases had developed progressive choroidal atrophy associated with visual loss. However, Wolf et al [18] never mentioned this striking picture, nor did Williams and Mieler [19] come across it in their extensive series of cases. It would, therefore, seem that both the course and outcome of APMPPE are influenced by variable pathogenetic mechanisms, or that different aetiological agents cause similar primary retinal epitheliopathy.…”

Section: Discussionmentioning

confidence: 98%

Progression of Choroidal Atrophy in Acute Posterior Multifocal Placoid Pigment Epitheliopathy

Daniele¹,

Daniele²,

Orcidi³

et al. 1997

Ophthalmologica

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Acute posterior multifocal placoid pigment epitheliopathy is a non-granulomatous chorioretinitis of uncertain origin that occurs in healthy young adults. The prevailing opinion is that the disease has a good long-term prognosis for visual acuity because it is self-limiting and chorioretinal scars do not enlarge with time. A middle-aged adult male who had acute posterior multifocal placoid pigment epitheliopathy in one eye has been followed for 22 years. After apparent clinical healing of the placoid epithelial lesions, widespread severe choroidal atrophy with visual loss occurred and progressed over years without interruption. To our knowledge this is the second report of progressive deterioration of a supposedly self-limiting chorioretinal disease.

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Section: Discussionmentioning

confidence: 98%

Progression of Choroidal Atrophy in Acute Posterior Multifocal Placoid Pigment Epitheliopathy

Daniele¹,

Daniele²,

Orcidi³

et al. 1997

Ophthalmologica

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“…Acute posterior multifocal placoid pigment epitheliopathy presents with central scotomata and PCS [9, 140, 214]. Binocular involvement is typical [9, 62].…”

Section: Disorders With Pcsmentioning

confidence: 99%

Central and Paracentral Visual Field Defects and Driving Abilities

Petzold¹,

Plant²

2005

Ophthalmologica

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“…2 Eighty per cent of affected eyes may have a final visual acuity of 6/12 or better. 13 However, a more recent study of 15 patients by Roberts and Mitchell 10 found visual acuities of 6/6 or better in 57 per cent of eyes, 6/9 to 6/18 in 14 per cent, 6/24 to 6/60 in 18 per cent and worse that 6/60 in 11 per cent of eyes.…”

Section: Prognosismentioning

confidence: 99%

“…13 However, a more recent study of 15 patients by Roberts and Mitchell 10 found visual acuities of 6/6 or better in 57 per cent of eyes, 6/9 to 6/18 in 14 per cent, 6/24 to 6/60 in 18 per cent and worse that 6/60 in 11 per cent of eyes. Most patients have residual symptoms and paracentral scotomata 2 and those with persistent central and paracentral scotomata and recurrent cases tend to have poorer visual outcomes. 8 Two years after onset visual acuities were still right 6/6 -and left 6/6 = and the phoria was still manifest.…”

Section: Prognosismentioning

confidence: 99%