Long-Term Treatment of Trichotillomania (Hair Pulling)

Swedo, Susan E.; Lenane, Marge; Leonard, Henrietta L.

doi:10.1056/nejm199307083290220

Cited by 68 publications

(33 citation statements)

References 3 publications

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“…Even in the case of clomipramine, however, there is little evidence that initial benefits are maintained. 11 Given the lack of clearly effective pharmacologic treatments for trichotillomania, additional treatment options are needed.…”

mentioning

confidence: 99%

N-Acetylcysteine, a Glutamate Modulator, in the Treatment of Trichotillomania

Grant

Odlaug

Kim

2009

Arch Gen Psychiatry

375

285

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mentioning

confidence: 99%

N-Acetylcysteine, a Glutamate Modulator, in the Treatment of Trichotillomania

Grant

Odlaug

Kim

2009

Arch Gen Psychiatry

375

285

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“…Inconsistent data have been reported regarding the durability of symptom improvement with pharmacologic agents for TTM. A subsequent follow-up to Swedo et al’s [75] initial clomipramine investigation revealed maintenance of gains for several years for several patients [84]. Similarly, Bennaroche [85] reported maintenance of treatment response to fluoxetine while remaining on the drug for greater than 1 year in more than half of their cohort.…”

Section: Overlap Between Ttm and Ocdmentioning

confidence: 98%

“…Some reports demonstrate maintenance of treatment benefit [84, 85] whereas other studies report symptom recurrence during treatment with the active agent [86, 87] or after medication discontinuation [85]. A recent small-sized retrospective review of hairpullers treated with clomipramine, fluoxetine or fluvoxamine reports that all treatment responders relapsed after initial improvement [173].…”

Section: Treatment Modalities and Intervention Research In Trichotillmentioning

confidence: 99%

Trichotillomania: Current Issues in Conceptualization and Treatment

Keuthen

OʼSullivan²,

Sprich-Buckminster³

1998

Psychother Psychosom

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Trichotillomania is a little-known disorder with wider prevalence and more significant consequences than previously believed. While sharing similarities with obsessive-compulsive disorder, compelling differences from it have also been noted. This fact, coupled with recognized overlap with other obsessive-compulsive spectrum disorders, has resulted in the ongoing evolution of our conceptualization of this illness. While empirical evidence supports the use of behavioral treatment and pharmacotherapy, considerable research is still needed before we can promise highly effective interventions tailored to the individual hairpuller. This review will summarize the evidence supporting, as well as challenging, a hypothesized link with obsessive-compulsive disorder. Current treatment approaches will be reviewed, as well as evidence for their efficacy. Suggestions will be made for future directions in this field.

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“…Em estudo duplo-cego de 10 semanas com 13 pacientes, utilizando a Trichotillomania Impairment Scale como instrumento de avaliação, a clomipramina demonstrou ser superior à desipramina, reduzindo os sintomas de arrancar cabelo após o tratamento cruzado 77 . Com base nesses resultados, Swedo et al 111 propuseram que a clomipramina tinha um efeito "antitricotilomaníaco". Contudo, a resposta individual de longo prazo para clomipramina variou significativamente, com uma redução global de 40% dos sintomas após um acompanhamento de quatro anos 111 .…”

Section: Tratamento Farmacológicounclassified

“…Com base nesses resultados, Swedo et al 111 propuseram que a clomipramina tinha um efeito "antitricotilomaníaco". Contudo, a resposta individual de longo prazo para clomipramina variou significativamente, com uma redução global de 40% dos sintomas após um acompanhamento de quatro anos 111 . Pacientes com transtorno de ansiedade ou transtornos de personalidade apresentaram menor resposta ao tratamento 92 .…”

Section: Tratamento Farmacológicounclassified

Tricotilomania

Toledo¹,

Taragano²,

Córdas³

2010

Rev. psiquiatr. clín.

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ResumoContexto: Relatada desde a Antiguidade, a tricotilomania (TTM) somente na última década despertou maior interesse clínico, sendo incluída no DSM-IV-TR (The Diagnostic and Statistical Manual of Mental Disorders 4 th Text Revision) como um transtorno do controle dos impulsos não especificado. Dados recentes estimam uma prevalência em torno de 3%, indicando uma incidência mais comum do que se imaginava. Aspectos clínicos e terapêuticos ainda não estão totalmente definidos. Objetivo: Revisão sistemática da literatura de vários aspectos da tricotilomania pertinentes à teoria clínica e prática. Método: Os termos "trichotillomania", "epidemiology", "clinical characteristics", "etiology", "comorbidity" e "treatment" foram consultados nas bases de dados Medline/PubMed, Lilacs, PsycINFO e Cochrane Library. Resultados: Pesquisas com populações não clínicas sugerem que a TTM é mais comum do que se acreditava. Aspectos fenomenológicos, taxonômicos, comorbidades e possibilidades terapêuticas são discutidos. Conclusão: Apesar de um crescente número de estudos recentes, questões clínicas e terapêuticas permanecem em aberto. Com base nesta revisão da literatura, sugerem-se direções para diagnóstico, tratamento e futuras pesquisas.Toledo EL, et al. / Rev Psiq Clín. 2010;37(6):251-9 Palavras-chave: Tricotilomania, etiologia, epidemiologia, diagnóstico, tratamento. AbstractBackground: Recognized since antiquity, only within the last decade has the subject of trichotillomania provoked any larger clinical interest since it has been included in the DSM-IV-TR (The Diagnostic and Statistical Manual of Mental Disorders 4 th Text Revision) as a disturbance of the impulse-control disorders not elsewhere classified. Recent data estimates its prevalence at around 3%. Although more common than it was imagined before, clinical and therapeutic aspects are still not well defined. Objective: Systematic revision in the literature of several aspects of trichotillomania and its clinical and practical theory. Method: The term "trichotillomania", "its epidemiology", "clinical characteristics", "etiology", "comorbidity" and "treatment" were searched in the data bases of Medline/ PubMed, Lilacs, PsycINFO and Cochrane Library. Results: Research with no clinical populations suggests that TTM is more common than it was previously suspected. Phenomenological and taxonomical aspects, comorbidity as well as therapeutic possibilities are discussed. Conclusion: Despite a growing number of recent studies, clinical and therapeutic aspects remain undefined. Based on this literature's review, directions are suggested concerning diagnosis, treatment and future research.

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Long-Term Treatment of Trichotillomania (Hair Pulling)

Cited by 68 publications

References 3 publications

N-Acetylcysteine, a Glutamate Modulator, in the Treatment of Trichotillomania

N-Acetylcysteine, a Glutamate Modulator, in the Treatment of Trichotillomania

Trichotillomania: Current Issues in Conceptualization and Treatment

Tricotilomania

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