Long-term survival of children following acute peritoneal dialysis in a resource-limited setting

Alao, Michael Abel; Ibrahim, Olayinka Rasheed; Asinobi, Adanze Onyenonachi; Akinsola, A

doi:10.23876/j.krcp.20.055

Cited by 7 publications

(2 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PD was usually carried out with nasogastric tubes adapted as PD catheters. Additional fenestrations were created at the distal end of the nasogastric tube, and the tube was then inserted into the peritoneal cavity by surgical technique or by a trocar method [2,[24][25][26]. More recently, we have inserted the fenestrated nasogastric tubes by a modified Seldinger technique [12].…”

Section: Methodsmentioning

confidence: 99%

Paediatric Dialysis at a Tertiary Hospital in South-West Nigeria: A 4-Year Report

et al. 2022

Self Cite

View full text Add to dashboard Cite

Introduction: Dialysis is potentially lifesaving in children with acute kidney injury (AKI) or chronic kidney disease (CKD), but availability is limited in low-income countries and lower-middle-income countries (LMICs). Methods: In the present study, we perform a 4-year study of patients who received peritoneal dialysis (PD) or haemodialysis (HD) at the Paediatric Nephrology Unit of the University College Hospital Ibadan, Nigeria. Subgroup analysis was performed on patients with sepsis or malaria AKI who underwent HD or PD for predictors of in-hospital mortality. Results: A total of 167 children aged 7 days to 18 years, median 7 (interquartile range 3–12) years, (60.5% males) were studied. In total, 129 (77.2%) had AKI, while 38 had CKD. Regarding AKI, 83 children (64.3%) received HD only, 42 underwent PD only, while 4 underwent both HD and PD. Malaria AKI was treated with HD in 43 (51.8%) or PD in 8 (10.5%), while sepsis AKI was treated with HD in 20 (21.4%) or PD in 33 (78.6%). Mortality in AKI was 16.3% overall, 10.8% in children on HD only, and 26.2% in children on PD only. Patients with sepsis AKI had higher mortality compared to patients with malaria AKI (RR 7.96 [1.70–37.37]). Subgroup analysis showed that age, diagnosis, and dialysis modality were not independent risk factors for mortality. The aetiology of CKD was glomerulonephritis in 26 (68.4%): treatment was HD in 36 and PD in 2 with mortality being 26.3%. Conclusions: PD for AKI showed relatively good outcomes in a LMIC. However, funding and support for a formal dialysis program for the management of AKI and CKD are needed.

show abstract

Section: Methodsmentioning

confidence: 99%

Paediatric Dialysis at a Tertiary Hospital in South-West Nigeria: A 4-Year Report

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

“…The guidelines recommend periodic reevaluation of peritonitis characteristics. However, few long-term studies have been conducted to investigate changes in peritonitis characteristics, despite the frequently reported crosssectional studies on peritonitis incidence [4,[12][13][14]. In North America, the NAPRTCS evaluated changes in peritonitis occurrence over time and demonstrated a decline in the incidence rates of peritonitis from 0.79 episodes/patient year in the 1992-1996 period to 0.44 episodes/patient year in the 2007-2010 period [6].…”

mentioning

confidence: 99%

Decreased incidence of peritoneal dialysis-associated peritonitis in young children

Park

Ahn

Kang

et al. 2023

Preprint

View full text Add to dashboard Cite

Background Peritonitis is the most common complication of peritoneal dialysis (PD). This study aimed to investigate changes in the incidence, risk factors, microbiology, and clinical outcomes of PD-associated peritonitis in the past decades. Methods This was a retrospective study that included children who initiated chronic PD at Seoul National University Children’s Hospital between 2000 and 2017. The patients were divided into two groups according to the year of initiation: those who initiated PD between 2000 and 2008 and those who initiated PD between 2009 and 2017. The follow-up data until PD cessation, death, or June 30, 2023, were reviewed. The incidence and characteristics of peritonitis were compared between the groups. Results A total of 184 patients (107 males and 77 females) with a median age of 10.2 years were included in this study. Of the patients, 92 experienced 210 episodes of peritonitis. Automated PD was the dominant PD modality in the later period. The incidence rate of peritonitis decreased from 0.35 to 0.21 episodes/patient year during the study period (P = 0.001). No changes were observed in the distribution of causative organisms. Subgroup analysis showed an increase in the 2-year peritonitis-free rate from 26.9–93.3% in children under 2 years of age. No significant difference in the 2-year peritonitis-free rate was observed among different age groups since 2009. Conclusions The incidence of PD-associated peritonitis decreased, particularly in children under 2 years of age. Thus, younger age is no longer a risk factor for PD-associated peritonitis.

show abstract

Peritoneal Dialysis in a Low-Resource Setting

Alao

Palmer

Njini

et al. 2022

Pediatric Procedural Adaptations for Low-Resource Settings

View full text Add to dashboard Cite

Long-term survival of children following acute peritoneal dialysis in a resource-limited setting

Cited by 7 publications

References 32 publications

Paediatric Dialysis at a Tertiary Hospital in South-West Nigeria: A 4-Year Report

Paediatric Dialysis at a Tertiary Hospital in South-West Nigeria: A 4-Year Report

Decreased incidence of peritoneal dialysis-associated peritonitis in young children

Peritoneal Dialysis in a Low-Resource Setting

Contact Info

Product

Resources

About