Long-term Survival of a Feline with Primary Aldosteronism Secondary to an Adrenal Carcinoma

Abstract

A female spayed domestic shorthair with an estimated age of 8 to 10 years was presented with chief complaints of cervical ventroflexion, seizure, and collapse. Blood examination revealed hypokalemia, and abdominal radiography and ultrasound examination showed a mass cranial to the right kidney, possibly originating from the right adrenal gland. Medical treatment for hypokalemia resulted in minimal improvement of the clinical signs. Additional examination revealed a high aldosterone level and low serum renin activity. The mass was removed and histopathologically diagnosed as an adrenal adenocarcinoma. Based on these results, the cat was diagnosed with primary aldosteronism secondary to an adrenal adenocarcinoma. The cat exhibited rapid postsurgical improvement in the clinical signs and hypokalemia. The cat survived for an additional 4 years 5 months.