Long-term survival and risk stratification in patients with angina at rest undergoing medical treatment

Servi, Stefano De; Berzuini, Carlo; Poma, E.; Ferrario, Maurizio; Ghio, Stefano; Scirè, A.; Cioffi, Paolo; Ardissino, Diego; Montemartini, C; Specchia, Giuśeppe

doi:10.1016/0167-5273(89)90134-4

Cited by 14 publications

(5 citation statements)

References 35 publications

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“…End point statistical evaluation was performed with the log rank test and the Mantel-Haenszel test. All significant variables identified in univariate analysis and also indices that have been used to stratify unstable angina patients for risk2 16 17 18 19 20 were entered into a multivariate one step logistic regression model. Statistical analysis was by the SAS statistical software package (SAS Institute Inc, Cary, North Carolina; version 6.08).…”

Section: Methodsmentioning

confidence: 99%

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Prospective study of the role of cardiac troponin T in patients admitted with unstable angina

Stubbs

Collinson

Moseley

et al. 1996

BMJ

173

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Section: Methodsmentioning

confidence: 99%

“…Unstable angina represents a critical phase of ischaemic heart disease and is associated with a significant risk of subsequent myocardial infarction or death 1 2 3 4 5 6 7. A subset of patients with unstable angina have raised concentrations of the cardiac specific protein troponin T8 9 10 11 in their serum early in the admission period.…”

Section: Introductionmentioning

confidence: 99%

Prospective study of the role of cardiac troponin T in patients admitted with unstable angina

Stubbs

Collinson

Moseley

et al. 1996

BMJ

173

View full text Add to dashboard Cite

show abstract

“…The adverse prognostic implications of unstable angi na pectoris have been previously reported [1][2][3][4], Myocar dial ischemia has been found to exist both with and with out chest pain. Identification of ischemia with or without anginal symptoms may therefore represent a valuable strategy for identification of those at increased risk for major ischemic sequelae [5].…”

Section: Introductionmentioning

confidence: 99%

Prognostic Information from On-Line Vectorcardiography in Unstable Angina Pectoris

Lundin

Eriksson

Fredrïkson³

et al. 1995

Cardiology

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The prognostic information from 24-hour monitoring with on-line vectorcardiography (VCG) was assessed in 100 patients with a clinical diagnosis of unstable angina pectoris. ST change vector magnitude, ST vector magnitude and QRS vector difference were monitored. During a follow-up period of 343 ± 77 days, 7 patients died from cardiac causes and 8 patients had a nonfatal myocardial infarction (MI). Thirty patients were readmitted for unstable angina pectoris and 36 were revascularized because of medical refractory angina. Univariate predictors of cardiac death or nonfatal MI included greater age, rest pain during hospitalization, previous MI, diabetes mellitus and high incidence of supposedly ischemic transient ST and QRS vector changes. In multivariate analysis, a high incidence of transient ST (p < 0.01) and QRS (p < 0.01) vector changes provided additional prognostic information beyond that of clinical and exercise test data. In conclusion, VCG monitoring during the first 24 h of hospitalization for unstable angina pectoris identifies patients with increased risk of adverse cardiac events.

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“…The mortality rate in our study was higher than that of prior studies in stable angina without COPD because of differing study populations. Patients with confirmed coronary lesions have a worse prognosis compared with those with no significant lesion [11,14]. Our study, however, showed no mortality or admission rate difference in the groups with and without significant lesions.…”

Section: Discussionmentioning

confidence: 51%

Prognosis in Patients Having Chronic Obstructive Pulmonary Disease with Significant Coronary Artery Lesion Angina

Park

Kim

Koo

et al. 2012

Korean J Intern Med

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Background/AimsMany studies have investigated angina and its relationship with chronic obstructive pulmonary disease (COPD). However, angina was diagnosed only by noninvasive tests or only by clinical symptoms in most of these studies. The aim of this study was to compare the prognosis, including rate of hospitalization and death from significant coronary artery lesion and nonsignificant coronary artery lesion angina, in patients with COPD.MethodsPatients with COPD who underwent coronary angiography (CAG) due to angina were reviewed retrospectively at a tertiary referral hospital. COPD is defined as post-bronchodilator forced expiratory volume in 1 sec/forced vital capacity (FEV1/FVC) of < 70%. A significant coronary lesion is defined as at least 50% diameter stenosis of one major epicardial artery in CAG.ResultsIn total, 113 patients were enrolled. Mean follow-up duration was 39 ± 21 months. Of the patients, 52 (46%) had mild COPD and 48 (42%) had moderate COPD. Sixty-nine (61%) patients had significant stenosis in CAG. The death rate in the follow-up period was 2.21 per 100 patient-years. No significant difference was observed among the all-cause mortality rate, admission rate, or intensive care unit admission rate in patients who had COPD with or without significant coronary artery disease. Pneumonia or acute exacerbation of COPD was the most common cause of admission.ConclusionsIn patients having COPD with angina who underwent CAG, no significant difference was observed in mortality or admission events depending on the presence of a significant coronary artery lesion during the 2-year follow-up period.

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Long-term survival and risk stratification in patients with angina at rest undergoing medical treatment

Cited by 14 publications

References 35 publications

Prospective study of the role of cardiac troponin T in patients admitted with unstable angina

Prospective study of the role of cardiac troponin T in patients admitted with unstable angina

Prognostic Information from On-Line Vectorcardiography in Unstable Angina Pectoris

Prognosis in Patients Having Chronic Obstructive Pulmonary Disease with Significant Coronary Artery Lesion Angina

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