2014
DOI: 10.2460/javma.245.5.527
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Long-term survival and quality of life in dogs with clinical signs associated with a congenital portosystemic shunt after surgical or medical treatment

Abstract: Surgical treatment of CPSS in dogs resulted in significantly improved survival rate and lower frequency of ongoing clinical signs, compared with medical management. Age at diagnosis did not affect survival rate and should not influence treatment choice.

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Cited by 61 publications
(88 citation statements)
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“…Surgery to attenuate the shunting vessel, thus re‐directing the hepatic portal blood flow to the liver, is the recommended treatment in most animals (Greenhalgh et al . ). The liver has a great capacity for regeneration via hyperplasia.…”
Section: Introductionmentioning
confidence: 97%
“…Surgery to attenuate the shunting vessel, thus re‐directing the hepatic portal blood flow to the liver, is the recommended treatment in most animals (Greenhalgh et al . ). The liver has a great capacity for regeneration via hyperplasia.…”
Section: Introductionmentioning
confidence: 97%
“…Long‐term medical management to control clinical signs associated with CPSS, particularly hepatic encephalopathy, is considerably less effective than surgery. It is only recommended in cases with predicted poor surgical outcome . Therefore, an accurate preoperative model for predicting the outcome of shunt attenuation is essential.…”
Section: Introductionmentioning
confidence: 99%
“…Hepatic insufficiency can cause a myriad of clinical signs, such as seizures, ataxia, obtundation, anorexia, vomiting, diarrhea, pollakiuria, stranguria, and death . The severity of these signs justifies surgical correction aimed at improving the perfusion of the deprived liver . Surgical techniques are generally classified as extravascular or intravascular and achieve partial or complete attenuation.…”
Section: Introductionmentioning
confidence: 99%
“…Surgical techniques are generally classified as extravascular or intravascular and achieve partial or complete attenuation. Complete occlusion of CIHPSS is rarely feasible without inducing unacceptable portal hypertension; instead, partial or gradual occlusion techniques have been applied most frequently . Extravascular partial suture ligation was reported most commonly in the veterinary literature through the turn of the 20th century .…”
Section: Introductionmentioning
confidence: 99%