Long-term Success of Nonvital, Immature Permanent Incisors Treated With a Mineral Trioxide Aggregate Plug and Adhesive Restorations: A Case Series from a Private Endodontic Practice

Ree, Marga; Schwartz, Richard S.

doi:10.1016/j.joen.2017.02.017

Cited by 47 publications

(37 citation statements)

References 45 publications

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“…Previous studies showed that ultrasonic activation of MTA apical plug increases the filling density, compressive strength, resistance to bacterial penetration, adaptation, and bonding strength to the root canals and enhances its physical properties (Parashos, Phoon, & Sathorn, 2014). For this reason, several case reports have recommended the use of ultrasonic activation for apical plug placement (Holden, Schwartz, Kirkpatrick, & Schindler, 2008;Ree & Schwartz, 2017). The increased adaptation and decreased bacterial penetration might stem from the increased penetration of the materials by ultrasonic activation (Guimarães et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

“…Thus, the placement of a bioactive material as an apical plug and backfilling of the canal during one or two visits is a viable and predictable treatment for nonvital immature permanent teeth (Bonte, Beslot, Boukpessi, & Lasfargues, ). Recent case studies also showed predictable long‐term tooth survival (10–15 years) of nonvital immature teeth treated with an apical plug technique (Pace, Giuliani, Nieri, Di Nasso, & Pagavino, ; Ree & Schwartz, ).…”

Section: Introductionmentioning

confidence: 95%

“…Recent case studies also showed predictable long-term tooth survival (10-15 years) of nonvital immature teeth treated with an apical plug technique (Pace, Giuliani, Nieri, Di Nasso, & Pagavino, 2014;Ree & Schwartz, 2017).…”

Section: Introductionmentioning

confidence: 95%

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Effect of ultrasonic activation on dentinal tubule penetration of calcium silicate‐based cements

Aksel

Arslan

Puralı

et al. 2019

Microscopy Res & Technique

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This study investigated the dentinal tubule penetration of mineral trioxide aggregate (MTA), NeoMTA Plus and Biodentine placed by either manual condensation or ultrasonic activation in simulated open apex model. Standardized divergent open apex models were created using palatal roots of 60 human maxillary molars and divided into six groups according to the used cements and activation methods (n = 10): MTA‐manual condensation, MTA‐ultrasonic activation, NeoMTA Plus‐manual condensation, NeoMTA Plus‐ultrasonic activation, Biodentine‐manual condensation, Biodentine‐ultrasonic activation. For the measurement of penetration, the cements were mixed with 0.1% Rhodamin B and 6‐mm apical portions of each root canal were obturated in an orthograde direction. The roots were embedded into acrylic blocks, and 1‐mm‐thick sections were obtained at 3 mm from the apex. Specimens were mounted onto glass slides and scanned under a confocal laser scanning microscope (CLSM) and stereomicroscope. Dentinal tubule penetration areas, depth and percentage were measured using LSM and ImageJ software. The data were analyzed using two‐way analysis of variance (anova) with Bonferroni correction (α = 0.05). No correlation was found between stereomicroscope and CLSM analyses (p > .05). CLSM analysis showed no significant differences between MTA, NeoMTA Plus, and Biodentine groups when manual condensation was used (p > .05). Ultrasonic activation did not increase the tubular penetration of MTA, NeoMTA Plus or Biodentine as compared to manual condensation of each material (p > .05). MTA, NeoMTA Plus and Biodentine showed similar tubular penetration when manual condensation was used. Ultrasonic activation of these cements had no effect on tubular penetration of each material as compared to the manual condensation counterparts.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 95%

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Effect of ultrasonic activation on dentinal tubule penetration of calcium silicate‐based cements

Aksel

Arslan

Puralı

et al. 2019

Microscopy Res & Technique

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“…Thus, radical treatment such as apexi cation, apical barrier surgery, or regenerative endodontic treatment (RET) should be performed for immature teeth [1]. Although an apical barrier can be established by apexi cation and apical barrier surgery, they do not help restore a functional pulp-dentin complex and do not allow further root development, leaving the tooth susceptible to fracture [2][3][4][5]. In recent studies, RET provided a new treatment modality for the previously described cases.…”

Section: Introductionmentioning

confidence: 99%

Clinical and Radiographic Outcomes of Vital Inflamed Pulp Therapy in Immature Permanent Teeth with Irreversible Pulpitis: A Retrospective Case Series

Xiao¹,

Shi²,

Wang³

2020

Preprint

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Background To assess the resolution of clinical symptoms and radiographic changes in root length and apical diameter in immature permanent teeth with irreversible pulpitis or apical periodontitis with vital inflamed pulp therapy (VIPT).Methods The faculty members at the Ninth People’s Hospital pediatric dentistry department were invited to submit consecutive VIPT cases treated by them, irrespective of outcome, between 2014 and 2016. Clinical success rate, radiographic changes in periapical radiolucency, and apical closure were analyzed, and radiographic changes in the apical diameter and root length were quantified.Results Thirteen of 14 submitted cases of irreversible pulpitis in immature teeth met the inclusion criteria. The follow-up period ranged from 17 to 37 (average, 26.5 ± 7) months. All 13 treated teeth (100%) survived and 12 (92.3%) met the clinical criteria for success throughout the follow-up period, with 92.3% of cases (12 of 13) showing a significant periapical radiolucency decrease and 84.6% (11 of 13) showing complete apical closure at the last visit. The change in apical diameter and root length were obvious. Conclusions Vital inflamed pulp therapy approaches might be of particular value in restoring root development and apical closure and can be an option in treating immature teeth with irreversible pulpitis, even apical periodontitis.

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“… 2 – 5 Since MTA is basically fabricated from Portland cement after excluding the toxic metal complex, the MTA has three essential components and a single modifier, namely, tricalcium silicate (C3S), dicalcium silicate (C2S), tricalcium aluminate (C3A), and bismuth oxide for radiopacity. 6 …”

Section: Introductionmentioning

confidence: 99%

Reformulated mineral trioxide aggregate components and the assessments for use as future dental regenerative cements

et al. 2018

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Mineral trioxide aggregate, which comprises three major inorganic components, namely, tricalcium silicate (C3S), dicalcium silicate (C2S), and tricalcium aluminate (C3A), is promising regenerative cement for dentistry. While mineral trioxide aggregate has been successfully applied in retrograde filling, the exact role of each component in the mineral trioxide aggregate system is largely unexplored. In this study, we individually synthesized the three components, namely, C3S, C2A, and C3A, and then mixed them to achieve various compositions (a total of 14 compositions including those similar to mineral trioxide aggregate). All powders were fabricated to obtain high purity. The setting reaction of all cement compositions was within 40 min, which is shorter than for commercial mineral trioxide aggregate (~150 min). Over time, the pH of the composed cements initially showed an abrupt increase and then plateaued (pH 10–12), which is a typical behavior of mineral trioxide aggregate. The compression and tensile strength of the composed cements increased (2–4 times the initial values) with time for up to 21 days in an aqueous medium, the degree to which largely depended on the composition. The cell viability test with rat mesenchymal stem cells revealed no toxicity for any composition except C3A, which contained aluminum. To confirm the in vivo biological response, cement was retro-filled into an extracted rat tooth and the complex was re-implanted. Four weeks post-operation, histological assessments revealed that C3A caused significant tissue toxicity, while good tissue compatibility was observed with the other compositions. Taken together, these results reveal that of the three major constituents of mineral trioxide aggregate, C3A generated significant toxicity in vitro and in vivo, although it accelerated setting time. This study highlights the need for careful consideration with regard to the composition of mineral trioxide aggregate, and if possible (when other properties are satisfactory), the C3A component should be avoided, which can be achieved by the mixture of individual components.

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Long-term Success of Nonvital, Immature Permanent Incisors Treated With a Mineral Trioxide Aggregate Plug and Adhesive Restorations: A Case Series from a Private Endodontic Practice

Cited by 47 publications

References 45 publications

Effect of ultrasonic activation on dentinal tubule penetration of calcium silicate‐based cements

Effect of ultrasonic activation on dentinal tubule penetration of calcium silicate‐based cements

Clinical and Radiographic Outcomes of Vital Inflamed Pulp Therapy in Immature Permanent Teeth with Irreversible Pulpitis: A Retrospective Case Series

Reformulated mineral trioxide aggregate components and the assessments for use as future dental regenerative cements

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