Long-Term Success of GUT-Directed Group Hypnosis for Patients With Refractory Irritable Bowel Syndrome: A Randomized Controlled Trial

Moser, Gabriele; Trägner, Silja; Gajowniczek, Ewelina Elwira; Mikulits, Andrea; Michalski, Maria; Kazemi-Shirazi, Lili; Kulnigg-Dabsch, Stefanie; Führer, Martina; Ponocny‐Seliger, Elisabeth; Dejaco, Clemens; Miehsler, Wolfgang

doi:10.1038/ajg.2013.19

Cited by 112 publications

(120 citation statements)

References 34 publications

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“…30 Results are in accordance with adult IBS trials showing that HT is superior to a variety of control treatments, with long-lasting effects. [63][64][65][66] Working mechanisms of HT are still poorly understood, but outcomes of adult studies hypothesize that HT affects both physiologic processes, such as colonic motility and pain-processing brain regions, and psychological factors, such as stress and dysfunctional cognitions. [67][68][69] CBT aims to change attitudes, cognitions, and behavior that may play a role in generating or maintaining symptoms and is effective in improving pain and other IBS symptoms in adults.…”

Section: Alternative Medicinementioning

confidence: 99%

Nonpharmacologic Treatment of Functional Abdominal Pain Disorders: A Systematic Review

et al. 2015

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BACKGROUND AND OBJECTIVE: Various nonpharmacologic treatments are available for pediatric abdominal pain-related functional gastrointestinal disorders (AP-FGIDs). Data on efficacy and safety are scarce. The goal of this study was to summarize the evidence regarding nonpharmacologic interventions for pediatric AP-FGIDs: lifestyle interventions, dietary interventions, behavioral interventions, prebiotics and probiotics, and alternative medicine.METHODS: Searches were conducted of the Medline and Cochrane Library databases. Systematic reviews and randomized controlled trials (RCTs) concerning nonpharmacologic therapies in children (aged 3-18 years) with AP-FGIDs were included, and data were extracted on participants, interventions, and outcomes. The quality of evidence was assessed by using the GRADE approach.RESULTS: Twenty-four RCTs were found that included 1390 children. Significant improvement of abdominal pain was reported after hypnotherapy compared with standard care/wait-list approaches and after cognitive behavioral therapy compared with a variety of control treatments/wait-list approaches. Written self-disclosure improved pain frequency at the 6-month follow-up only. Compared with placebo, Lactobacillus rhamnosus GG (LGG) and VSL#3 were associated with significantly more treatment responders (LGG relative risk: 1.31 [95% confidence interval: 1.08 to 1.59]; VSL#3: P , .05). Guar gum significantly improved irritable bowel syndrome symptom frequency; however, no effect was found for other fiber supplements (relative risk: 1.17 [95% confidence interval: 0.75 to 1.81]) or a lactose-free diet. Functional disability was not significantly decreased after yoga compared with a wait-list approach. No studies were found concerning lifestyle interventions; gluten-, histamine-, or carbonic acid-free diets; fluid intake; or prebiotics. No serious adverse effects were reported. The quality of evidence was found to be very low to moderate. CONCLUSIONS:Although high-quality studies are lacking, some evidence shows efficacy of hypnotherapy, cognitive behavioral therapy, and probiotics (LGG and VSL#3) in pediatric AP-FGIDs. Data on fiber supplements are inconclusive.

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Section: Alternative Medicinementioning

confidence: 99%

Nonpharmacologic Treatment of Functional Abdominal Pain Disorders: A Systematic Review

et al. 2015

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“…Validierungsstudien bezüglich der Rom I-III Kriterien sind nur spärlich vorhanden [8]; eine kürzlich publizierte Arbeit zeigte eine Sensitivität der aktuell gebräuchlichen Rom III Kriterien (Tabelle 1) für die Diagnose eines RDS durch Allgemeinpraktiker von 75% [11]. [27]. Im Gegensatz dazu hat sich die Akupunktur in mehreren…”

Section: Bis Zu 25% Aller Ambulanten Gastroenterologischen Patienten unclassified

Reizdarmsyndrom – Diagnostik und Therapie

Pohl¹,

Heinrich²,

Misselwitz³

2013

Gastroenterologe

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“…As we were conducting our meta-analysis, advance online publication of this study was reported in February 2013, so we have included it in our review. 24 Agreement between authors for trial eligibility was substantial (k statistic = 0.79).…”

Section: Study Selection and Data Extractionmentioning

confidence: 99%

“…1). 11,[20][21][22][23][24] One study reported 2 RCTs being conducted on different settings in one publication. 20 One of the studies that we initially excluded was published only in abstract form.…”

Section: Study Selection and Data Extractionmentioning

confidence: 99%

The Efficacy of Hypnotherapy in the Treatment of Irritable Bowel Syndrome: A Systematic Review and Meta-analysis

Lee¹,

Choi²,

Choi³

2014

J Neurogastroenterol Motil

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Background/AimsHypnotherapy is considered as a promising intervention for irritable bowel syndrome (IBS), but the evidence is still limited. The aims of this study were to conduct a systematic review and meta-analysis to estimate the efficacy of hypnotherapy for the treatment of IBS. MethodsA literature search was performed using MEDLINE (PubMed), Embase, PsycINFO and the Cochrane Central Register of Controlled Trials (CENTRAL database). Only randomized controlled trials that compared hypnotherapy with any other conventional treatment or no treatment in patients with IBS were included. Studies had to report outcomes as IBS symptom score or quality of life. The mean change in outcome score was used to pool these outcomes for the meta-analysis. Data were synthesized using the standardized mean difference for continuous data. ResultsSeven randomized controlled trials (6 papers) involving 374 patients with IBS were identified. Performance bias was high in all trials because it was impossible to blind participants and therapists in this type of intervention. The outcomes in this meta-analysis were evaluated at 3 months for short-term effects and at 1 year for long-term effects. The change in abdominal pain score at 3 months was significant in the hypnotherapy group (standardized mean difference, -0.83; 95% CI, -1.65 to -0.01). Three of the 4 trials showed greater improvement in overall gastrointestinal symptoms in the hypnotherapy group. ConclusionsThis study provides clearer evidence that hypnotherapy has beneficial short-term effects in improving gastrointestinal symptoms of patients with IBS.

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Long-Term Success of GUT-Directed Group Hypnosis for Patients With Refractory Irritable Bowel Syndrome: A Randomized Controlled Trial

Abstract: GHT improves IBS-related QOL, is superior to SMT alone, and shows a long-term effect even in refractory IBS.

Cited by 112 publications

References 34 publications

Nonpharmacologic Treatment of Functional Abdominal Pain Disorders: A Systematic Review

Nonpharmacologic Treatment of Functional Abdominal Pain Disorders: A Systematic Review

Reizdarmsyndrom – Diagnostik und Therapie

The Efficacy of Hypnotherapy in the Treatment of Irritable Bowel Syndrome: A Systematic Review and Meta-analysis

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