Long‐term risk of herpes zoster following COVID‐19: A retrospective cohort study of 2 442 686 patients

Huang, Shih‐Wei; Yeh, Wen‐Bin; Chen, Hui‐Yuan; Yong, Su‐Boon

doi:10.1002/jmv.29101

Cited by 1 publication

(1 citation statement)

References 6 publications

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“…The TriNetX database shares electronic medical record data (diagnoses, procedures, medications, laboratory values, genomic information, and types of visits) of approximately 140 million individuals at 119 healthcare organizations (HCOs) [ 20 ]. Numerous observational studies have utilized the TriNetX database, particularly when conducting COVID-19 research [ 21 , 22 , 23 , 24 ]. The TriNetX platform provides integrated tools for analyzing patient-level data and presents outcomes to researchers as consolidated reports.…”

Section: Methodsmentioning

confidence: 99%

Malnutrition and the Post-Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Multi-Institutional Population-Based Propensity Score-Matched Analysis

Lee,

Liang,

Hsu

et al. 2024

Life

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Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global health crisis, exacerbating issues like malnutrition due to increased metabolic demands and reduced intake during illness. Malnutrition, a significant risk factor, is linked to worse outcomes in patients with COVID-19, such as increased mortality and extended hospital stays. This retrospective cohort study investigated the relationship between malnutrition and clinical outcomes within 90–180 days using data obtained from the TriNetX database. Patients aged >18 years diagnosed with COVID-19 between 1 January 2022, and 31 March 2024 were enrolled in the study. The propensity score-matching (PSM) method was used to match patients with malnutrition (malnutrition group) and those without malnutrition (control group). The primary composite outcome was the cumulative hazard ratio (HR) for post-COVID-19 condition, all-cause hospitalization, and all-cause mortality between 90 days and 180 days after COVID-19 diagnosis. The secondary outcomes were the individual components of the primary outcomes. Two cohorts, each consisting of 15,004 patients with balanced baseline characteristics, were identified using PSM. During the 90–180-day follow-up period, the malnutrition group exhibited a higher incidence of all-cause hospitalization, mortality, or post-COVID-19 condition (HR = 2.315, 95% confidence interval: 2.170–2.471, p < 0.0001). Compared with patients with COVID-19 without malnutrition, those with malnutrition may be associated with a higher risk of adverse clinical outcomes.

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