Long-term risk of fibroid recurrence after laparoscopic myomectomy

Radosa, MP; Owsianowski, Z; Mothes, A; Weisheit, Anja; Vorwergk, J.; Asskaryar, F.A.; Camara, O.; Bernardi, T.; Runnebaum, I. B.

doi:10.1016/j.ejogrb.2014.05.029

Cited by 68 publications

(58 citation statements)

References 36 publications

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“…These short-term results cannot be generalized to mid- and long-term outcomes. Fibroid recurrence and persistent postoperative infertility can affect quality of life and sexual function in the long term, thereby; altering the long-term outcomes of initially successful treatment [19, 34]. We did not assess fibroid recurrence or fertility rates in this study because valid information could not be obtained within the follow-up period.…”

Section: Discussionmentioning

confidence: 99%

“…Laparoscopic myomectomy was performed in the lithotomy position using four ports as described previously [18]: one 10-mm optic trocar inserted through the umbilicus; two 5-mm working trocars inserted through the infero-lateral abdominal wall, two fingers’ distance above the iliac crest; and one 15-mm working trocar in the suprapubic area, two fingers`distance above the symphysis pubis. The laparoscopic technique used in this study has been described in detail elsewhere [18, 19]. A diluted (1:200.000) epinephrine solution (Xylonest, Astra-Zeneca, Wedel/Germany) was injected into the serosa and the myometrium overlying the fibroid for vasoconstriction.…”

Section: Methodsmentioning

confidence: 99%

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Postoperative Quality of Life and Sexual Function in Premenopausal Women Undergoing Laparoscopic Myomectomy for Symptomatic Fibroids: A Prospective Observational Cohort Study

Radosa

Radosa²,

Mavrova

et al. 2016

PLoS ONE

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IntroductionUterine leiomyomas are the most common benign gynecologic tumors. To date laparoscopy myomectomy is the gold standard for treatment of symptomatic fibroids in reproductive-aged women. Detailed counseling about the effects of this procedure on postoperative sexuality and quality of life is important in these patients. However, available data on these subjects are limited and contradictory. The aim of this study was to assess sexual function and quality of life in premenopausal women undergoing laparoscopic myomectomy for symptomatic uterine fibroids.Material and MethodsAll premenopausal women who underwent laparoscopic myomectomy for symptomatic fibroids between April 2012 and August 2014 at a tertiary university center were enrolled in this prospective observational cohort study. Sexual function and quality of life were assessed for the pre- and postoperative (six months post-operatively) state using two validated questionnaires, the Female Sexual Function Index (FSFI) and the European Quality of Life Five-Dimension Scale (EQ-5D).ResultsNinety-five of the 115 (83%) eligible patients completed the study. Overall a significant improvement in quality of life and sexual function was observed in the study cohort: Median FSFI (28 (18.7–35.2)) and EQ-5D scores (1 (0.61–1) after laparoscopic myomectomy were significantly higher than preoperative scores (21.2 (5.2–33.5); 0.9 (0.2–1); p ≤ 0.01). The number, position and localization of the largest fibroids were not correlated with pre- or postoperative sexual function or quality of life.ConclusionLaparoscopic myomectomy might have positive short-term effects on postoperative quality of life and sexual function in premenopausal women suffering from symptomatic fibroids.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Postoperative Quality of Life and Sexual Function in Premenopausal Women Undergoing Laparoscopic Myomectomy for Symptomatic Fibroids: A Prospective Observational Cohort Study

Radosa

Radosa²,

Mavrova

et al. 2016

PLoS ONE

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show abstract

“…However, these treatments are associated with the risk of tumor recurrence and need for additional surgeries. [7][8][9][10] In recent years, several new procedures have been approved for the treatment of UF, including high-intensity focused ultrasound, and radiofrequency ablation. [7][8][9] Given the high prevalence of UF, the associated debilitating symptoms affecting daily activities, and the invasiveness of treatment options, the economic burden of UF is considerable.…”

Section: A N U S C R I P Tmentioning

confidence: 99%

The direct and indirect costs of uterine fibroid tumors: a systematic review of the literature between 2000 and 2013

Soliman

Yang

et al. 2015

American Journal of Obstetrics and Gynecology

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“…Particularly, patients with multiple uterine fibroids and those in the third decade of life showed an increased risk of symptomatic recurrence after surgery [10]. After myomectomy the pregnancy rate was about 20-50% in patients with otherwise unknown cause of infertility.…”

Section: Introductionmentioning

confidence: 99%

A Successful Live Birth with In Vitro Fertilization from a Woman with a Huge Uterus Due to Recurrent Multiple Uterine Fibroids after Abdominal Myomectomies

Yang¹,

Chen²

2016

JFIV Reprod Med Genet

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Long-term risk of fibroid recurrence after laparoscopic myomectomy

Cited by 68 publications

References 36 publications

Postoperative Quality of Life and Sexual Function in Premenopausal Women Undergoing Laparoscopic Myomectomy for Symptomatic Fibroids: A Prospective Observational Cohort Study

Postoperative Quality of Life and Sexual Function in Premenopausal Women Undergoing Laparoscopic Myomectomy for Symptomatic Fibroids: A Prospective Observational Cohort Study

The direct and indirect costs of uterine fibroid tumors: a systematic review of the literature between 2000 and 2013

A Successful Live Birth with In Vitro Fertilization from a Woman with a Huge Uterus Due to Recurrent Multiple Uterine Fibroids after Abdominal Myomectomies

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