Long-term results of the edge-to-edge repair for failed mitral valve repair as a bailout option

Zhong, Zhaoji; Yue, Zi-Qi; Zhao, Zhenhua; Song, Wu; Zheng, Shanshan; Liu, Sheng

doi:10.1007/s11748-020-01433-z

Cited by 7 publications

(10 citation statements)

References 20 publications

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“…In studies that reported re-repair procedures in detail ( 15 , 17 , 24 , 35 ), the most frequently used techniques include leaflet resection, ring removal/annuloplasty, edge-to-edge repair, and neochordae. Simple techniques such as edge-to-edge repair may be an effective choice ( 36 ). The technique should be selected based on individual mitral valve lesions, while the basic principles and steps of MVr outlined by Carpentier should always be adhered to.…”

Section: Discussionmentioning

confidence: 99%

Re-repair vs. Replacement for Failed Mitral Valve Repair: A Systemic Review and Meta-Analysis

Zhong

et al. 2022

Front. Cardiovasc. Med.

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ObjectiveThe objective of this study was to compare outcomes of re-repair with those of mitral valve replacement (MVR) for failed initial mitral valve repair (MVr).MethodsWe searched the Pubmed, Embase, and Cochrane Library databases for studies that compared mitral valve re-repair with MVR for the treatment of failed initial MVr. Data were extracted by two independent investigators and subjected to a meta-analysis. Odds ratio (OR), risk ratio (RR), hazard ratio (HR), ratio difference (RD), mean difference (MD), and 95% confidence interval (CI) were calculated with the Mantel-Haenszel and inverse-variance methods for mode of repair failure, perioperative outcomes, and follow-up outcomes.ResultsEight retrospective cohort studies were included, with a total of 938 patients, and mean/median follow-up ranged from 1.8 to 8.9 years. Pooled incidence of technical failure was 41% (RD: 0.41; 95% CI: 0.32 to 0.5; P = 0.00; I2 = 86%; 6 studies, 846 patients). Pooled mitral valve re-repair rate was 36% (RD: 0.36; 95% CI: 0.26–0.46; P = 0; I2 = 91%; 8 studies, 938 patients). Pooled data showed significantly lower perioperative mortality (RR: 0.22; 95% CI: 07 to 0.66; I2 = 0%; P = 0.008; 6 studies, 824 patients) and significantly lower long-term mortality (HR:0.42; 95% CI: 0.3 to 0.58; I2 = 0%; P = 0; 7 studies, 903 patients) in the re-repair group compared with MVR.ConclusionsMitral valve re-repair was associated with better immediate and sustained outcomes for failed MVr and should be recommended if technically feasible.

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Section: Discussionmentioning

confidence: 99%

Re-repair vs. Replacement for Failed Mitral Valve Repair: A Systemic Review and Meta-Analysis

Zhong

et al. 2022

Front. Cardiovasc. Med.

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“…Recent data about specific results of rerepair surgeries are limited. A recent analysis involving 26 patients treated by surgical edge-to-edge repair for failed MV repair reported a freedom from reoperation and ≥ moderate MR at 10 years of 69.9 ± 11.7%, and a mean MV gradient of 6.1 ± 2.5 mmHg [16]. A monocentric analysis encompassing 57 patients who underwent reoperation because of annuloplasty ring dehiscence reported 30-day, 1year and 5-year mortality rates of 2%, 89% and 74%, respectively [17].…”

Section: Discussionmentioning

confidence: 99%

Transcatheter edge-to-edge repair following surgical valve repair with ring implantation: Results from the multicentre “Clip-in-Ring” registry

Leurent

Auffret

Grinberg

et al. 2022

Archives of Cardiovascular Diseases

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“…Concomitant mitral valve repair in this group of patients should be done using a simply method (23). If there is doubt regarding repair durability, mitral valve replacement should be selected without hesitation.…”

Section: Surgery Techniquementioning

confidence: 99%

Surgical and Conservative Treatment of Post-infarction Left Ventricular Pseudoaneurysm

Zhong

Song

Zheng

et al. 2022

Front. Cardiovasc. Med.

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BackgroundPost-infarction left ventricular (LV) pseudoaneurysm is a rare mechanical complication of myocardial infarction that carries a substantial risk of sudden rupture. The purpose of this study was to compare the surgical results of post-infarction LV pseudoaneurysm with those of conservative treatment.MethodsFrom 2016 to 2021, 22 patients were hospitalized for LV pseudoaneurysm, including 17 cases (77.3%) caused by myocardial infarction. Of the 17 patients, 10 (58.8%) underwent surgical repair, while seven (41.2%) were treated medically. The clinical course, echocardiograph data, and surgical outcomes were analyzed. Survival rates of the surgical and conservative groups were compared.ResultsThere were no perioperative deaths. Intra-aortic balloon pumping support was required in two (20%) patients. No follow-up mortality was observed in the surgical group and at the last follow-up, all the patients were classified as New York Heart Association class I–II. In the conservative group, there was one (14.3%) hospital death and two (28.6%) additional deaths during follow-up. A significant difference was found in survival between the two groups (P = 0.024).ConclusionsSurgical repair of post-infarction LV pseudoaneurysm can be performed with good results, while conservative treatment carries a significant risk of sudden death. Surgical repair is indicated for every patient diagnosed, even those with a small pseudoaneurysm without symptoms.

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Long-term results of the edge-to-edge repair for failed mitral valve repair as a bailout option

Cited by 7 publications

References 20 publications

Re-repair vs. Replacement for Failed Mitral Valve Repair: A Systemic Review and Meta-Analysis

Re-repair vs. Replacement for Failed Mitral Valve Repair: A Systemic Review and Meta-Analysis

Transcatheter edge-to-edge repair following surgical valve repair with ring implantation: Results from the multicentre “Clip-in-Ring” registry

Surgical and Conservative Treatment of Post-infarction Left Ventricular Pseudoaneurysm

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