Long-Term Results of Split-Skin Grafting in Combination with Excimer Laser for Stable Vitiligo

Abstract

Combination treatment with split-skin-thickness grafting and postsurgical exposure to 308-nm excimer laser in patients with stable focal or segmental vitiligo can lead to fast, cosmetically good, long-lasting results.

Melanocyte-keratinocyte transplantation procedure in the treatment of vitiligo: The experience of an academic medical center in the United States

“…It should be noted that posttransplantation phototherapy has been used in a number of studies as part of a standardized protocol. 18,21,22 Additional studies that compare repigmentation in patients who undergo surgical treatment alone versus those who receive adjuvant therapies are needed.…”

Ultrathin split-thickness skin grafting followed by narrowband UVB therapy for stable vitiligo: An effective and cosmetically satisfying treatment option

“…These surgical procedures basically donate some viable melanocytes to the affected area of depigmentation. These viable melanocytes are then stimulated by different means like PUVA or PUVAsol therapy, [5][6][7] narrowband UVB (NBUVB), [8][9][10] topical steroids, [11] and even excimer laser treatment [12] to cause melanin production and thereby causing a repigmentation of the recipient or treated area.…”

Comparative study between excimer light and topical antioxidant versus excimer light alone for treatment of vitiligo

“…Although excimer laser is more efficient in inducing T-cell apoptosis than excimer light (8) , Casacci et al 2007 clinical study show a similar efficacy between the two light sources in the treatment of vitiligo (6) .…”

“…has been shown to be more effective than conventional NB-UVB (6) With the recent advent of various antioxidants for the treatment of dermatological conditions, we hypothesized that the combined action of the excimer light plus topical antioxidant hydrogel could be synergistic in the treatment of vitiligo, thereby increasing the quality of regimentation. 3 In this study we aim to compare the efficacy of combined topical antioxidant (2), lower limbs (2), elbows (2), knees (6), Wrist (2), Ankle (3), and Dorsum of fingers (3).…”

“…3 In this study we aim to compare the efficacy of combined topical antioxidant (2), lower limbs (2), elbows (2), knees (6), Wrist (2), Ankle (3), and Dorsum of fingers (3).…”