Long-term results of radical surgery for rectal cancer: multivariate analysis of prognostic factors influencing survival and local recurrence

Local recurrence after curative resection for rectal cancer is associated with anterior position of the tumour

“…These include tumour level within the rectum 20 -22 , tumour size 23 , macroscopic morphology 24 , distal clearance 3,22,25 , circumferential clearance 26 -28 , depth of tumour invasion 28 -31 , lymph node metastasis 21,23,26,29 -31 , number of involved nodes 25,32 , tumour stage 3,6,20,22,24,33 -35 , grade of differentiation 20,23,26,28,32 , infiltrating tumour margin 26 , vascular invasion 3,6,22,26 , sex 22 , age 25,31 , intraoperative spillage of tumour cells 6,20 , anastomotic leakage 22,34 , experience and specialization of the surgeon 6,20 , surgical technique 3,22,35 , interhospital variability 20 and adjuvant therapy 6,23,31,33 . However, an extensive literature search by the authors failed to find any publications in which the position of the tumour was considered as a possible risk factor for local recurrence, although in one study position was found to be associated with cancer-specific mortality 36 .…”

Diagnostic Accuracy of MRI for Assessment of T Category, Lymph Node Metastases, and Circumferential Resection Margin Involvement in Patients with Rectal Cancer: A Systematic Review and Meta-analysis

“…Each item is scored as yes/no/unclear. Bias items include elements of study design and execution (items 3,4,5,6,7,12,14), and interpretation (items 10,11), and generalizability items refer to the composition of patients selected (items 1,2). The…”

Beckeneviszeration beim rezidivierten und lokal weit fortgeschrittenen Rektumkarzinom

“…Bei Tumoren des oberen Rektumdrittels erfolgt die TME mindestens 5 cm distal des makroskopischen Tumorrands, gemessen in vivo. Das Mesorektum sollte hierbei horizontal durchtrennt werden, um eine vollständige Tumorentfernung sicherzustellen [27]. Dieser Sicherheitsabstand resultiert aus der Beobachtung, dass bei T3-und T4-Rektumkarzinomen in seltenen Fällen Satellitenknoten oder Lymphknotenmetastasen in bis zu 4 cm distal des makroskopischen Tumorrands vorkommen können [32].…”