Long-Term Results of Initial and Repeated Partial Splenic Embolization for the Treatment of Chronic Idiopathic Thrombocytopenic Purpura

Kimura, Fumio; Itoh, Hiroshi; Ambiru, Satoshi; Shimizu, Hiroaki; Togawa, Akira; Yoshidome, Hiroyuki; Ohtsuka, Masayuki; Shimizu, Yasuhiko; Shimamura, Fumihiko; Miyazaki, Masaru

doi:10.2214/ajr.179.5.1791323

Cited by 46 publications

(32 citation statements)

References 14 publications

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“…Kimura et al (44) reported the results of initial (n ϭ 39) and repeat partial splenic arterial embolization (n ϭ 12) in patients with chronic idiopathic thrombocytopenic purpura. The therapeutic effects of initial and repeat partial splenic arterial embolization were classified as complete response if the patient's platelet count increased to more than 100 ϫ 10 9 /L without steroids 1 year after the initial or repeat embolization, as partial response if the platelet count increased by 50 -100 ϫ 10 9 /L, or as no response.…”

Section: Results Of Partial Embolizationmentioning

confidence: 99%

Splenic Arterial Interventions: Anatomy, Indications, Technical Considerations, and Potential Complications

Madoff

Denys

Wallace³

et al. 2005

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Splenic arterial interventions are increasingly performed to treat various clinical conditions, including abdominal trauma, hypersplenism, splenic arterial aneurysm, portal hypertension, and splenic neoplasm. When clinically appropriate, these procedures may provide an alternative to open surgery. They may help to salvage splenic function in patients with posttraumatic injuries or hypersplenism and to improve hematologic parameters in those who otherwise would be unable to undergo high-dose chemotherapy or immunosuppressive therapy. Splenic arterial interventions also may be performed to exclude splenic artery aneurysms from the parent vessel lumen and prevent aneurysm rupture; to reduce portal pressure and prevent sequelae in patients with portal hypertension; to treat splenic artery steal syndrome and improve liver perfusion in liver transplant recipients; and to administer targeted treatment to areas of neoplastic disease in the splenic parenchyma. As the use of splenic arterial interventions increases in interventional radiology practice, clinicians must be familiar with the splenic vascular anatomy, the indications and contraindications for performing interventional procedures, the technical considerations involved, and the potential use of other interventional procedures, such as radiofrequency ablation, in combination with splenic arterial interventions. Familiarity with the complications that can result from these interventional procedures, including abscess formation and pancreatitis, also is important.

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Section: Results Of Partial Embolizationmentioning

confidence: 99%

Splenic Arterial Interventions: Anatomy, Indications, Technical Considerations, and Potential Complications

Madoff

Denys

Wallace³

et al. 2005

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256

189

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show abstract

“…The timing of the splenectomy is dependent upon the clinical picture of the patient after definitive management of the life-threatening hemorrhage. Because thrombocytopenia has been reported to frequently recur when splenic embolization is performed for chronic ITP [15,16], removal of the spleen should be undertaken at the earliest time that is determined to be safe and practical. With a skilled interventional radiologist and proper facilities, splenic embolization appears to be a fast and safe alternative to emergent operative splenectomy.…”

Section: Discussionmentioning

confidence: 99%

Splenic artery embolization in the management of an acute immune thrombocytopenic purpura–related intracranial hemorrhage

Puapong

Terasaki

Lacerna

et al. 2005

Journal of Pediatric Surgery

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“…According to reports in the literature, partial splenic embolization has been safely performed to increase thrombocyte counts in cases of portal hypertension [15], hypersplenism [16], chronic immune thrombocytopenic purpura [17], and hemoglobinopathy [18]. In our case, we had exhausted all other treatment options, and decided to try partial splenic embolization due to the patient's grave condition.…”

Section: Fig 2 Computed Tomography Of the Upper Abdomen One Day Aftmentioning

confidence: 94%

Partial Splenic Embolization in Myelodysplastic Syndrome Associated with Immune Thrombocytopenia

Özdoğu

Boğa

Oğuzkurt

et al. 2004

J Thromb Thrombolysis

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Long-Term Results of Initial and Repeated Partial Splenic Embolization for the Treatment of Chronic Idiopathic Thrombocytopenic Purpura

Abstract: Partial splenic embolization combined with repeated embolization may be an effective alternative to splenectomy in the treatment of chronic idiopathic thrombocytopenic purpura.

Cited by 46 publications

References 14 publications

Splenic Arterial Interventions: Anatomy, Indications, Technical Considerations, and Potential Complications

Splenic Arterial Interventions: Anatomy, Indications, Technical Considerations, and Potential Complications

Splenic artery embolization in the management of an acute immune thrombocytopenic purpura–related intracranial hemorrhage

Partial Splenic Embolization in Myelodysplastic Syndrome Associated with Immune Thrombocytopenia

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