Long‐term results of endoscopic resection for type I gastric neuroendocrine tumors

Abstract

Long-term follow-ups with 22 patients suggest that endoscopic resection of Type 1 gastric NETs is a safe and effective treatment option with a relatively low recurrence rate.

ENETS Consensus Guidelines Update for Gastroduodenal Neuroendocrine Neoplasms

“…Previously, the ENETS guidelines recommended surveillance after 1-2 years and resection for lesions ≥1 cm or those threatening the deep muscularis propria to avoid metastatic spread. Some investigators have advocated resecting all visible lesions using biopsy forceps for small lesions and endoscopic mucosal resection (EMR) for lesions >5 mm [18,19]; however, there are no randomized data comparing an aggressive endoscopic approach (resecting all visible tumors) to more selective endoscopic therapy (resecting only larger lesions). The overall metastatic risk is low in type 1 g-NENs and has been directly correlated with tumor size (10 mm appearing to be the cut-off) [20].…”

Clinical management of patients with gastric neuroendocrine neoplasms associated with chronic atrophic gastritis: a retrospective, multicentre study

“…Current European Neuroendocrine Tumor Society (ENETS) guidelines for the management of patients with type I gNENs suggest endoscopic management with lesion resection [11], while a surgical approach should be limited to cases of clearly demonstrated invasion beyond the submucosa and/or with metastases. The current literature points out the elevated variability which exists between treatments in cases of multiple, localized (mucosa or submucosa) type I gNENs: (1) careful endoscopic follow-up without any treatment [12][13][14], (2) somatostatin analog (SSA) therapy [9,15,16] and (3) endoscopic resection [10,17]. Two papers have recently been published in which a retrospective analysis of patients with type I gNENs treated with different approaches was carried out.…”

Nowotwory neuroendokrynne żołądka i dwunastnicy z uwzględnieniem gastrinoma (zasady postępowania rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)

“…After endoscopic treatment it is recommended that a surveillance examination is conducted every 12 months [54,55,56] In type 3 neoplasms, with the exception of small lesions that can be removed with ESD [57], the preferred method, as in other types deeply invading the organ wall, is surgical procedure.…”