Long-Term Results of Angioplasty Vs Stenting in Cardiac Transplant Recipients With Allograft Vasculopathy

Simpson, Leo; Lee, Eva K.; Hott, Brenda; Vega, David; Book, Wendy

doi:10.1016/j.healun.2004.10.005

Cited by 51 publications

(44 citation statements)

References 23 publications

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“…Options for revascularization are coronary artery bypass or percutaneous intervention, each presenting its own pitfalls. Frequently, the diffuse nature of the vasculopathy and vessel thickening precludes bypass grafting, while percutaneous coronary intervention has been shown to have higher rates of in-stent restenosis, target vessel revascularization, myocardial infarction and death as compared to non-transplant recipients 3 .…”

Section: Discussionmentioning

confidence: 99%

Percutaneous Coronary Intervention of Unprotected Left Main Coronary Artery in Cardiac Allograft Vasculopathy: A Case Series of Pediatric Patients

Stoletniy²,

Sakr³

et al. 2015

ICFJ

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<p>Cardiac allograft vasculopathy is a major cause of morbidity and mortality in orthotopic heart transplantation. The optimal management remains uncertain, especially in left main coronary artery lesions. With the limited data available in the literature, we present a review of three pediatric cases of cardiac allograft vasculopathy, involving the left main coronary artery, treated with percutaneous coronary intervention.</p>

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Section: Discussionmentioning

confidence: 99%

Percutaneous Coronary Intervention of Unprotected Left Main Coronary Artery in Cardiac Allograft Vasculopathy: A Case Series of Pediatric Patients

Stoletniy²,

Sakr³

et al. 2015

ICFJ

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“…The optimal treatment for allograft vasculopathy in OHT patients is unknown, but PCI appears to be a therapeutic option. One of the main concerns of PCI in OHT patients is re-stenosis, as the allografted coronary vessel is in a proinflammatory state, which influences vessel remodeling (13)(14)(15)(16). Multivariate analysis revealed that in allograft vasculopathy, the use of stents decreased the risk of restenosis (odds ratio 0.34, p<0.05) compared with cutting balloon or other PCI methods (10,17).…”

Section: Discussionmentioning

confidence: 99%

Treatment of Left Main Coronary Artery Stenosis with Drug-Eluting Stent Following Heart Transplantation

et al. 2012

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Cardiac allograft vasculopathy is the leading cause of death after the first year of heart transplantation. The optimal treatment for unprotected left main coronary artery disease in orthotopic heart transplantation (OHT) patients is unknown. Two OHT patients with left main disease following heart transplantation underwent percutaneous coronary intervention (PCI). Technical success was achieved in the patients with drug-eluting stents inserted to cover the lesions in the left main coronary artery. After 16 months follow-up, one patient died of multiorgan failure, the other was alive and free from myocardial infarction or target vessel revascularization. We conclude that the unprotected PCI for the left main coronary artery stenosis in transplanted heart is feasible.

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“…Although in a study comparing long-term results of stenting and angioplasty in allograft vasculopathy stenting has a lower restenosis rate at 6 and 12 months follow-up, 5 year restenosis rates were similar. 7 We performed PTCA without stenting. Stent implantation was not done because of the ectasia in this vessel segment, the diameter of the vessel was above 4.0 mm.…”

Section: Discussionmentioning

confidence: 99%

Successful Percutaneous Intervention to Acute Myocardial Infarction Presenting With Typical Chest Pain in Transplanted Heart

Bildirici

Ural

Şahı̇n

et al. 2009

Circ J

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Allograft coronary artery disease (CAD) is the main limiting factor of the long-term survival in cardiac transplant recipients. It is present in approximately 50% of patients at 5 years post-transplant. Allograft CAD might result in congestive heart failure, ventricular arrhythmias and sudden cardiac death. Acute coronary syndrome is a rare presentation of allograft CAD, because symptoms are usually atypical or absent as a result of cardiac denervation. However, it should be reminded that reinnervation of the transplanted heart might occur, and angina pectoris could be felt as a sign of an acute coronary syndrome. We present a 27-year-old female cardiac transplant patient with an acute myocardial infarction, who was successfully treated with percutaneous transluminal coronary angioplasty. (Circ J 2009; 73: 2166 -2168

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Long-Term Results of Angioplasty Vs Stenting in Cardiac Transplant Recipients With Allograft Vasculopathy

Cited by 51 publications

References 23 publications

Percutaneous Coronary Intervention of Unprotected Left Main Coronary Artery in Cardiac Allograft Vasculopathy: A Case Series of Pediatric Patients

Percutaneous Coronary Intervention of Unprotected Left Main Coronary Artery in Cardiac Allograft Vasculopathy: A Case Series of Pediatric Patients

Treatment of Left Main Coronary Artery Stenosis with Drug-Eluting Stent Following Heart Transplantation

Successful Percutaneous Intervention to Acute Myocardial Infarction Presenting With Typical Chest Pain in Transplanted Heart

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