“…Coronary artery bypass graft surgery effectively relieves angina in patients with coronary heart disease, 20 and in particular, in patients with multivessel coronary artery disease, bypass surgery can provide a better clinical outcome than percutaneous coronary angioplasty. 21 However, atherosclerosis develops in the grafts from about 3 years after the bypass operation [22][23][24] and only approximately 60% of saphenous vein grafts remain patent at 10-12 years after surgery because of the progression of atherosclerotic disease.…”