Long-term quality of life of patients treated in paediatric intensive care unit

Polić, Branka; Meštrović, Julije; Markić, Joško; Meštrović, Marija; Čapkun, Vesna; Utrobicic, Ina; Jukica, Mira; Radonić, Marija

doi:10.1007/s00431-012-1843-0

Cited by 46 publications

(44 citation statements)

References 24 publications

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“…Preexisting neurodevelopmental disease was a risk factor in one study (50), but this was contradicted in another study (41). In the first study, patients were at relatively good baseline function and neurologic deficits were likely mild (50), whereas in the second study, majority of the children had severely poor function prior to admission (41).…”

Section: Factors Associated With Acquired Functional Disabilitymentioning

confidence: 91%

“…Of particular importance is the rate of acquired functional impairment from critical illness as opposed to preexisting disease (76,77). Acquired functional impairment in a general PICU population ranged from 10% to 36% at discharge, to 26% at 6 months, and 10% to 13% when followed up at more than 2 years (5,37,39,41,44,46,47,50). A longitudinal study demonstrated that some impairment resolves with time as acquired impairment dropped from 26% at 6 months to 19% at 2 years after PICU admission (50).…”

Section: Functional Outcomes In Picu Survivorsmentioning

confidence: 97%

“…Greater illness severity as measured by the Pediatric Index of Mortality and Pediatric Risk of Mortality scores and longer PICU stay were also associated with acquired functional impairment (5,39,41,44,45,50).…”

Section: Factors Associated With Acquired Functional Disabilitymentioning

confidence: 98%

“…Only one study explored factors affecting recovery from acquired functional impairment (50) and found that children with chronic diseases were more likely to have persistent functional impairments 24 months after PICU admission.…”

Section: Factors Associated With Acquired Functional Disabilitymentioning

confidence: 99%

“…However, MGOS has not been as widely used as the POPC, and its validity in the PICU population requires further study. The Royal Alexandra Hospital for Children Measure of Function (RAHC MOF) requires clinicians to score a child on a 0-100 scale with the aid of descriptions on various functional skills (49,50).…”

Section: Types Of Measuresmentioning

confidence: 99%

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Functional Outcomes and Physical Impairments in Pediatric Critical Care Survivors: A Scoping Review*

Ong

Lee

Leow

et al. 2016

Pediatric Critical Care Medicine

131

109

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Functional impairment may be persistent in pediatric survivors of critical care. Unfortunately, studies varied largely in measurement timing and tools used. The lack of differentiation between impairment in different functional domains limited the generalizability of data. Further studies using a combination of standardized measures at various time points of the disease process can help establish more comprehensive rates of physical impairment.

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Section: Factors Associated With Acquired Functional Disabilitymentioning

confidence: 91%

Section: Functional Outcomes In Picu Survivorsmentioning

confidence: 97%

Section: Factors Associated With Acquired Functional Disabilitymentioning

confidence: 98%

Section: Factors Associated With Acquired Functional Disabilitymentioning

confidence: 99%

Section: Types Of Measuresmentioning

confidence: 99%

See 3 more Smart Citations

Functional Outcomes and Physical Impairments in Pediatric Critical Care Survivors: A Scoping Review*

Ong

Lee

Leow

et al. 2016

Pediatric Critical Care Medicine

131

109

View full text Add to dashboard Cite

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Epidemiology of Intensive Care Admissions for Children in the US From 2001 to 2019

et al. 2023

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ImportanceEstimates of the number of US children receiving intensive care unit (ICU) care and ICU admission patterns over time are lacking.ObjectiveTo determine how ICU admission patterns, use of critical care services, and the characteristics and outcomes of critically ill children have changed from 2001 to 2019.Design, Setting, and ParticipantsThis population-based retrospective cohort study used data from the Healthcare Cost and Utilization Project’s state inpatient databases from a total of 21 US states in 2001, 2004, 2010, 2016, and 2019. Hospitalized children aged 0 to 17 years, excluding newborns (during birth hospitalization), were included. Patients admitted to rehabilitation institutions or psychiatric hospitals were also excluded. Data were analyzed from July 2021 to December 2022.ExposuresCare in a nonneonatal ICU.Main Outcomes and MeasuresFrom extracted patient data, International Classification of Diseases, Ninth Revision, Clinical Modification, and Tenth Revision, Clinical Modification, codes were used to identify diagnoses, comorbid conditions, organ failures, and mechanical ventilation. Generalized linear Poisson regression and the Cuzick test were used to evaluate trends. US Census data were used to generate age- and sex-adjusted national estimates of ICU admissions and costs.ResultsOf 2 157 991 pediatric admissions, 275 656 (12.8%) included ICU care. The mean (SD) age was 6.43 (6.10) years; 121 894 individuals were female (44.2%), and 153 731 were male (55.8%). From 2001 to 2019, the prevalence of ICU care among hospitalized children increased from 10.6% to 15.5%. The percentage of ICU admissions in children’s hospitals rose from 51.2% to 85.1% (relative risk [RR], 1.66; 95% CI, 1.64-1.68). The percentage of children admitted to an ICU with an underlying comorbidity increased from 46.2% to 57.0% (RR, 1.23; 95% CI, 1.22-1.25), and the percentage with preadmission technology dependence increased from 16.4% to 23.5% (RR, 1.44; 95% CI, 1.40-1.48). The prevalence of multiple organ dysfunction syndrome increased from 6.8% to 21.0% (RR, 3.12; 95% CI, 2.98-3.26), while mortality decreased from 2.5% to 1.8% (RR, 0.72; 95% CI, 0.66-0.79). Hospital length of stay increased by 0.96 days (95% CI, 0.73-1.18) for ICU admissions from 2001 to 2019. After inflation adjustment, total costs for a pediatric admission involving ICU care nearly doubled between 2001 and 2019. Nationally, an estimated 239 000 children were admitted to a US ICU in 2019, corresponding to $11.6 billion in hospital costs.Conclusions and RelevanceIn this study, the prevalence of children receiving ICU care in the US increased, as did length of stay, technology use, and associated costs. The US health care system must be equipped to care for these children in the future.

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Functional Impairments in Pediatric Critical Illness Survivors

Ong

Puthucheary

2019

Annual Update in Intensive Care and Emergency Medicine 2019

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Long-term quality of life of patients treated in paediatric intensive care unit

Abstract: Acute illness has a significant impact both on children with and without CHC after treatment in PICU 6 months after discharge. Twenty-four months after discharge, comorbidity was identified as the decisive factor for diminished QOL in children after PICU treatment.

Cited by 46 publications

References 24 publications

Functional Outcomes and Physical Impairments in Pediatric Critical Care Survivors: A Scoping Review*

Functional Outcomes and Physical Impairments in Pediatric Critical Care Survivors: A Scoping Review*

Epidemiology of Intensive Care Admissions for Children in the US From 2001 to 2019

Functional Impairments in Pediatric Critical Illness Survivors

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