Long-Term Prognostic Value of Resting Heart Rate in Subjects With Prehypertension

King, Dana E.; Everett, Charles J.; Mainous, Arch G.; Liszka, Heather A.

doi:10.1016/j.amjhyper.2006.01.019

Cited by 57 publications

(45 citation statements)

References 32 publications

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“…39 Our study further indicated that, in general, the prevalence of hypertension was 17% for males and 14% for females. The prevalence of SHT was 14% It has been shown that high resting HR (tachycardia) is a strong predictor for death especially from cardiovascular diseases, [26][27][28][29] and hence the need to determine its prevalence early in the young adult population. A novel aspect of this study, therefore, is the evaluation of the prevalence of resting tachycardia in young Nigerian adults.…”

Section: Discussionmentioning

confidence: 99%

“…19,20 Hypertension is a strong predictor of cardiovascular diseases and death 21,22 and is also an important component of the metabolic syndrome, 23 which is a risk factor for coronary heart disease. 24,25 Several studies [26][27][28][29] have also shown that a high resting HR is a strong predictor for death especially from cardiovascular diseases.…”

Section: Introductionmentioning

confidence: 99%

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Relationship of body mass index with haemodynamic variables and abnormalities in young adults

Dimkpa

Oji

2009

J Hum Hypertens

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We aimed at investigating whether the degree of adiposity is related to haemodynamic variables such as systolic blood pressure (SBP), diastolic blood pressure (DBP) and resting heart rate (HR), and to haemodynamic abnormalities such as hypertension and resting tachycardia. A cross-sectional study was carried out among young students in Ebonyi State University, Nigeria. A total of 710 subjects (350 males and 360 females) aged 20-25 years were recruited for the study. Resting blood pressure and HR of subjects were measured and the body mass index (BMI) was calculated from height and weight measurements. The observed prevalences in this study were as follows: overweight, 20% in males and 26% in females; obesity, 8% in males and 6% in females; hypertension, 17% in males and 14% in females; and resting tachycardia, 22% in males and 24% in females. In both genders, BMI showed significant correlations (Po0.001 or Po0.01 or Po0.05) with SBP, DBP and HR after controlling for age and physical activity status, and SBP indicated the strongest association with BMI. Furthermore, the prevalence of hypertension and tachycardia increased with an increase in BMI level, whereas overweight/obese subjects indicated significantly higher risk of hypertension than did the non-overweight/obese controls. The present findings therefore strengthen the previously reported usefulness of BMI in predicting cardiovascular risks and add to our understanding of the early development of obesity-related cardiovascular abnormalities in young adults and the need to prevent obesity early in life and to avoid its unfavourable lifethreatening consequences later in life.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Relationship of body mass index with haemodynamic variables and abnormalities in young adults

Dimkpa

Oji

2009

J Hum Hypertens

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“…In fact, only the Atherosclerosis Risk in Communities studies 10 demonstrated a positive association between coronary heart disease and office heart rate but only limited to women in analyses without adjustment for blood pressure. 10 The Joint National Committee guideline, version 7, 40 stated that data from epidemiological studies and clinical trials have demonstrated that elevations in resting heart rate 4 and reduced heart rate variability 41 were associated with higher cardiovascular risk. This statement was mainly based on the Framingham Heart Study, 4,5 in which an average resting heart rate of 83 bpm, according to the expert committee, 40 was associated with a substantially higher risk of cardiovascular mortality.…”

Section: Discussionmentioning

confidence: 99%

“…S tudies in hypertensive patients [1][2][3][4] or populations [5][6][7][8][9][10][11][12] suggested that heart rate, either measured at rest 1,2,4 -7,9 -12 or by ambulatory blood pressure monitoring, [1][2][3] might be a predictor of total, [1][2][3][4][5][6][7][8][9][10][11][12] cardiovascular, 4,6,7,9,11 or noncardiovascular mortality. 1,5,6 However, as highlighted by a 2006 consensus document, 13 the evidence relating outcome to heart rate remains incomplete and lacks consistency.…”

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confidence: 99%

Prognostic Value of Ambulatory Heart Rate Revisited in 6928 Subjects From 6 Populations

et al. 2008

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Abstract-The evidence relating mortality and morbidity to heart rate remains inconsistent. We performed 24-hour ambulatory blood pressure monitoring in 6928 subjects (not on ␤-blockers; mean age: 56.2 years; 46.5% women) enrolled in prospective population studies in Denmark, Belgium, Japan, Sweden, Uruguay, and China. We computed standardized hazard ratios for heart rate, while stratifying for cohort, and adjusting for blood pressure and other cardiovascular risk factors. Over 9.6 years (median), 850, 325, and 493 deaths accrued for total, cardiovascular, and noncardiovascular mortality, respectively. The incidence of fatal combined with nonfatal end points was 805, 363, 439, and 324 for cardiovascular, stroke, cardiac, and coronary events, respectively. Twenty-four-hour heart rate predicted total (hazard ratio: 1.15) and noncardiovascular (hazard ratio: 1.18) mortality but not cardiovascular mortality (hazard ratio: 1.11) or any of the fatal combined with nonfatal events (hazard ratio: Յ1.02). Daytime heart rate did not predict mortality (hazard ratio: Յ1.11) or any fatal combined with nonfatal event (hazard ratio: Յ0.96). Nighttime heart rate predicted all of the mortality outcomes (hazard ratio: Ն1.15) but none of the fatal combined with nonfatal events (hazard ratio: Յ1.11). The night:day heart rate ratio predicted total (hazard ratio: 1.14) and noncardiovascular mortality (hazard ratio: 1.12) and all of the fatal combined with nonfatal events (hazard ratio: Ն1.15) with the exception of stroke (hazard ratio: 1.06). Sensitivity analyses, in which we stratified by risk factors or from which we excluded 1 cohort at a time or the events occurring within 2 years of enrollment, showed consistent results. In the general population, heart rate predicts total and noncardiovascular mortality. With the exception of the night:day heart rate ratio, heart rate did not add to the risk stratification for fatal combined with nonfatal cardiovascular events. Thus, heart rate adds little to the prediction of cardiovascular risk. (Hypertension. 2008;52:229-235.)

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“…c Fórmula de Cockroft-Gault. así como con la mortalidad por todas las causas [62][63][64][65] . Además, hay evidencia de que una frecuencia cardiaca elevada aumenta el riesgo de una hipertensión de nueva aparición 66,67 y se asocia con frecuencia a alteraciones metabólicas y al síndrome metabólico [67][68][69] . Sin embargo, dada la amplia gama de valores de la frecuencia cardiaca en reposo aceptados como normales (60-90 lat/min), no puede proponerse en la actualidad un valor de corte para aumentar la exactitud de la estratificación del riesgo cardiovascular total.…”

Section: Diabetes Mellitus Ecv O Renal Establecidaunclassified

Guías de práctica clínica para el tratamiento de la hipertensión arterial 2007

2007

Revista Española de Cardiología

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Long-Term Prognostic Value of Resting Heart Rate in Subjects With Prehypertension

Abstract: Resting heart rate is an easily accessible tool that may be helpful for stratifying CHD and mortality risk in people with prehypertension.

Cited by 57 publications

References 32 publications

Relationship of body mass index with haemodynamic variables and abnormalities in young adults

Relationship of body mass index with haemodynamic variables and abnormalities in young adults

Prognostic Value of Ambulatory Heart Rate Revisited in 6928 Subjects From 6 Populations

Guías de práctica clínica para el tratamiento de la hipertensión arterial 2007

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