Long term prognostic value of Coronary Computed Tomography Angiography in suspected coronary artery disease: A 62month median follow-up study

Al-Mallah, Mouaz; Qureshi, Waqas; Pantelic, Milan; Nour, Khaled

doi:10.1016/j.ijcard.2014.07.203

Cited by 12 publications

(6 citation statements)

References 7 publications

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“…The long-term prognostic value of CCTA was also confirmed [27]. However, the primary limitation of CCTA is a tendency to overestimate the severity of coronary artery stenosis compared to ICA, and only a minority of stenoses that are identified using CCTA are ischemia-causing [2][3][4].…”

Section: Discussionmentioning

confidence: 96%

Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in coronary artery disease: A systematic review and meta-analysis

Deng

Jing

Wang

et al. 2015

International Journal of Cardiology

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Section: Discussionmentioning

confidence: 96%

Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in coronary artery disease: A systematic review and meta-analysis

Deng

Jing

Wang

et al. 2015

International Journal of Cardiology

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“…In a study with long term follow up (mean of 80 months) in 4,244 symptomatic patients who underwent CCTA, mortality was 4.2% vs. 10.8% in 1706 patients who underwent standard of care [38]. In a study assessing long term follow up after a normal CCTA, the annual rate of major adverse events was 0.9% [39]. The CONFIRM registry followed 24,775 patients who underwent ≥64-detector row CCTA for a median of 2.3 years for the occurrence of death [40].…”

Section: Prognostic Value Of Cctamentioning

confidence: 99%

Cardiac CT vs. Stress Testing in Patients with Suspected Coronary Artery Disease: Review and Expert Recommendations

Rahsepar

Arbab‐Zadeh

2015

Curr Cardiovasc Imaging Rep

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Diagnosis and management of coronary artery disease represent a major challenge to our health care systems affecting millions of patients each year. Until recently, the diagnosis of coronary artery disease could be conclusively determined only by invasive coronary angiography. To avoid risks from cardiac catheterization, many healthcare systems relied on stress testing as gatekeeper for coronary angiography. Advancements in cardiac computed tomography angiography technology now allows to noninvasively visualize coronary artery disease, challenging the role of stress testing as the default noninvasive imaging tool for evaluating patients with chest pain. In this review, we summarize current data on the clinical utility of cardiac computed tomography and stress testing in stable patients with suspected coronary artery disease.

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“…CCTA is useful for noninvasive assessment of CAD in stable ischemic heart disease, as well as in patients with acute onset chest pain and acute coronary syndromes 34 – 36 . Studies have demonstrated its clinical utility and prognostic value in patients with suspected CAD with a very high negative predictive value 37 . However, CCTA overestimates the severity of stenotic lesions with only a minority of identified lesions being functionally ischemic therefore leading to increased utilization of ICA 4 , 38 , 39 .…”

Section: Discussionmentioning

confidence: 99%

Comparison of Computed Tomography derived Fractional Flow Reserve to invasive Fractional Flow Reserve in Diagnosis of Functional Coronary Stenosis: A Meta-Analysis

Agasthi

Kanmanthareddy

Khalil

et al. 2018

Sci Rep

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Computed Tomography derived Fractional Flow Reserve (CTFFR) is an emerging non-invasive imaging modality to assess functional significance of coronary stenosis. We performed a meta-analysis to compare the diagnostic performance of CTFFR to invasive Fractional Flow reserve (FFR). Electronic search was performed to identify relevant articles. Pooled Estimates of sensitivity, specificity, positive likelihood ratio (LR+), negative likelihood ratio (LR−) and diagnostic odds ratio (DOR) with corresponding 95% confidence intervals (CI) were calculated at the patient level as well as the individual vessel level using hierarchical logistic regression, summary receiver operating characteristic (SROC) curve and area under the curve were estimated. Our search yielded 559 articles and of these 17 studies was included in the analysis. A total of 2,191 vessels in 1294 patients were analyzed. Pooled estimates of sensitivity, specificity, LR+, LR− and DOR with corresponding 95% CI at per-patient level were 83% (79–87), 72% (68–76), 3.0 (2.6–3.5), 0.23 (0.18–0.29) and 13 (9–18) respectively. Pooled estimates of sensitivity, specificity, LR+, LR− and DOR with corresponding 95% CI at per-vessel level were 85% (83–88), 76% (74–79), 3.6 (3.3–4.0), 0.19 (0.16–0.22) and 19 (15–24). The area under the SROC curve was 0.89 for both per patient level and at the per vessel level. In our meta-analysis, CTFFR demonstrated good diagnostic performance in identifying functionally significant coronary artery stenosis compared to the FFR.

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Long term prognostic value of Coronary Computed Tomography Angiography in suspected coronary artery disease: A 62month median follow-up study

Cited by 12 publications

References 7 publications

Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in coronary artery disease: A systematic review and meta-analysis

Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in coronary artery disease: A systematic review and meta-analysis

Cardiac CT vs. Stress Testing in Patients with Suspected Coronary Artery Disease: Review and Expert Recommendations

Comparison of Computed Tomography derived Fractional Flow Reserve to invasive Fractional Flow Reserve in Diagnosis of Functional Coronary Stenosis: A Meta-Analysis

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