Long-term Prognosis of the Jejunal Involvement of Crohn’s Disease

Park, Soo-Kyung; Yang, Suk‐Kyun; Park, Seong Ho; Park, Sang Hyoung; Kim, Jong Wook; Yang, Dan; Jung, Kee Wook; Kim, Kyung Jo; Ye, Byong Duk; Byeon, Jeong‐Sik; Myung, Seung‐Jae; Yu, Chang Sik; Kim, Jin-Ho

doi:10.1097/mcg.0b013e3182705f9e

Cited by 47 publications

(52 citation statements)

References 46 publications

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“…Clinically, the superior sensitivity of VCE for proximal small bowel disease represents an important diagnostic advantage because proximal small bowel disease has recently been demonstrated to be a significant negative prognostic factor in CD in several studies. [21][22][23] …”

Section: Vce Versus Other Modalities For the Diagnosis Of CDmentioning

confidence: 98%

Video Capsule Endoscopy of the Small Bowel for Monitoring of Crohnʼs Disease

Kopylov

Ben‐Horin

Seidman

et al. 2015

Inflammatory Bowel Diseases

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Video capsule endoscopy has revolutionized our ability to visualize the small bowel mucosa. This modality is a valuable tool for the diagnosis of suspected small bowel Crohn's disease, and it is increasingly used for the monitoring of disease activity in patients with established small bowel Crohn's. The purpose of the current article was to review the literature pertaining to the utilization of capsule endoscopy in established Crohn's disease, for monitoring of mucosal healing, postoperative recurrence, disease classification, and other indications.

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Section: Vce Versus Other Modalities For the Diagnosis Of CDmentioning

confidence: 98%

Video Capsule Endoscopy of the Small Bowel for Monitoring of Crohnʼs Disease

Kopylov

Ben‐Horin

Seidman

et al. 2015

Inflammatory Bowel Diseases

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“…In the remaining 35-50% of patients, disease affects the ileocolonic area [2,3]; thus, the small bowel is affected in 70-80% of patients. Nowadays, there is evidence that up to 20% of patients with known CD have isolated jejunal involvement, although the exact frequency is not known [4][5][6][7]. Because of nonspecific symptoms and the absence of a gold-standard diagnostic method, the diagnosis of CD can be delayed for months [8,9].…”

Section: Introductionmentioning

confidence: 98%

The role of small bowel capsule endoscopy and ileocolonoscopy in patients with nonspecific but suggestive symptoms of Crohn’s disease

Mitselos

Christodoulou

Κατσάνος

et al. 2016

European Journal of Gastroenterology &Amp; Hepatology

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“…55 Jejunal involvement has been recognized as an independent marker of severity in CD, being associated with an increased risk of relapse, 55 higher use of corticosteroids (HR 1.24; 95% CI: 1.02 -1.50) and thiopurines (HR 1.26; 95% CI: 1.06 -1.49), higher rates of strictureplasties (RR 2.52; 95% CI: 1.60 -3.96), hospitalizations (RR 1.29; 95% CI: 1.14 -1.47), and longer hospitalization duration (RR, 1.30; 95% CI, 1.25 -1.34). 56 Recently, it was reported that treatment with thiopurines and/or biologics was started more often in patients with proximal small bowel lesions detected by SBCE [13/33 (39%) vs 1/17 (6%), p = 0.011, relative risk (RR) 6.5], particularly when severe (6%, 36% and 45% of patients with non-significant, mild and moderate-to-severe inflammation, respectively).…”

Section: Crohn's Diseasementioning

confidence: 99%

Current Clinical Indications for Small Bowel Capsule Endoscopy

Rosa

Cotter

2015

Acta Med Port

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RESUMOIntrodução: A enteroscopia por cápsula é o exame de primeira linha no diagnóstico de diversas patologias do intestino delgado. Este artigo tem por objectivo rever e analisar criticamente as indicações actuais para enteroscopia por cápsula na prática clínica. Material e Métodos: Revisão bibliográfica suportada em artigos indexados na PubMed. Resultados e Discussão: A enteroscopia por cápsula permite a avaliação não invasiva da mucosa do intestino delgado, com elevado rendimento diagnóstico. Em doentes com hemorragia digestiva de causa obscura, o rendimento da enteroscopia por cápsula aumenta quando realizada precocemente após o evento hemorrágico. O tratamento das angiectasias com enteroscopia assistida por balão permite diminuir a recidiva hemorrágica, enquanto o risco de recidiva em doentes com enteroscopia por cápsula "negativa" é controverso. A entero-TC/entero-RM podem superiorizar-se à enteroscopia por cápsula no diagnóstico de alguns tumores. O 'Smooth Protruding Index on Capsule Endoscopy' (score SPICE) auxilia na diferenciação entre verdadeiros tumores submucosos e abaulamentos não patológicos. A enteroscopia por cápsula é valiosa em doentes com suspeita de doença de Crohn quando a ileocolonoscopia não é diagnóstica, permitindo também estadiar a extensão e actividade das lesões em doentes com diagnóstico prévio de doença de Crohn, com potenciais implicações prognósticas e terapêuticas. A enteroscopia por cápsula permite ainda o diagnóstico de complicações em doentes com doença celíaca refractária. Conclusões: Actualmente, a importância da enteroscopia por cápsula é reconhecida no contexto da hemorragia digestiva de causa obscura e/ou suspeita de tumores do intestino delgado, bem como na suspeita de doença de Crohn ou em doentes com doença de Crohn conhecida para determinar a localização, extensão e actividade da doença, e ainda para a investigação de doentes com doença celíaca refractária. Palavras-chave: Doenças Intestinais; Endoscopia por Cápsula. ABSTRACT Introduction:Small bowel capsule endoscopy is currently the first line diagnostic examination for many diseases affecting the small bowel. This article aims to review and critically address the current indications of small bowel capsule endoscopy in clinical practice. Material and Methods: Bibliographic review of relevant and recent papers indexed in PubMed.

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Long-term Prognosis of the Jejunal Involvement of Crohn’s Disease

Abstract: Korean CD patients are more likely to have jejunal involvement than western patients. Jejunal involvement is one of the poor prognostic factors in Korean CD patients, as it is in westerners.

Cited by 47 publications

References 46 publications

Video Capsule Endoscopy of the Small Bowel for Monitoring of Crohnʼs Disease

Video Capsule Endoscopy of the Small Bowel for Monitoring of Crohnʼs Disease

The role of small bowel capsule endoscopy and ileocolonoscopy in patients with nonspecific but suggestive symptoms of Crohn’s disease

Current Clinical Indications for Small Bowel Capsule Endoscopy

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