Long-Term Prognosis of Mitral-Valve Prolapse

Mills, Peter; Rose, John; Hollingsworth, Jane; Amara, Ingrid A.; Craige, Ernest

doi:10.1056/nejm197707072970103

Cited by 201 publications

(31 citation statements)

References 25 publications

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“…494 -499 In most patients, the MVP syndrome is associated with a benign prognosis. 500,501 The age-adjusted survival rate for both men and women with MVP is similar to that of individuals without this entity. 485 The gradual progression of MR in patients with MVP may result in the progressive dilatation of the left atrium and ventricle.…”

Section: Pathophysiology and Natural Historymentioning

confidence: 85%

2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

Bonow¹,

Carabello²,

Chatterjee³

et al. 2008

Circulation

910

259

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Section: Pathophysiology and Natural Historymentioning

confidence: 85%

2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

Bonow¹,

Carabello²,

Chatterjee³

et al. 2008

Circulation

910

259

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“…Based upon the criteria utilized, mitral valve prolapse may occur in approximately 6% of the young female and a lesser percentage of the young male population. [1][2][3][4][5] Many patients are symptom-free, but most have associated chest pain, palpitations, dyspnea, fatigue, and lightheadedness. Although it has generally been regarded as a benign syndrome, four major complications have been recognized: [6][7][8] (1) progressive mitral regurgitation, (2) spontaneous rupture of the chorda tendineae, (3) sudden death believed due to ventricular fibrillation (occurring in 1.2 to 1.6%), and (4) bacterial endocarditis (which occurs in 3% of patients).…”

mentioning

confidence: 99%

Cerebral ischemic events in patients with mitral valve prolapse.

Sandok¹,

Giuliani²

1982

Stroke

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SUMMARY All patients 20 years old or older referred for echocardiographic examination and found to have mitral valve prolapse during the period January 1975 through December 1979 were included in the study. Of the 1,138 patients, two-thirds were women and one-third were men. Their average age was 48.4 years. Forty patients (3.5%) had histories of prior focal cerebrovascular ischemic events. In 26 of the 40 patients, no responsible mechanism other than mitral valve prolapse was identified, and in 4, the ischemic event occurred during an episode of bacterial endocarditis, a known complication of mitral valve prolapse. In 10 of the 26 patients, there was clinical information to suggest an embolic mechanism for the ischemia. A conservative estimate of the prevalence rate for cerebral infarction in this group of patients is four times greater than the rate expected in a normal population. This difference is likely due to the contribution of mitral valve prolapse in the pathogenesis of cerebral infarction. Stroke, Vol 13, No 4, 1982 MITRAL VALVE PROLAPSE is a relatively common condition. Based upon the criteria utilized, mitral valve prolapse may occur in approximately 6% of the young female and a lesser percentage of the young male population.

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“…Because of such apparent similarity, simple symptomatic evaluation may lead to serious misdiagnoses and se quelae in those patients who suffer from MVPS, namely mitral regurgitation, bacte rial endocarditis, cerebral embolism and even sudden death [13].…”

Section: Introductionmentioning

confidence: 99%

Panic Disorder Associated with Mitral Valve Prolapse: Psychosomatic Implications

Krakowski

1987

Psychother Psychosom

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Findings of the second part of the clinical study initiated in 1982 are presented. Both aimed to determine possible clinical differences among panic disorder, agoraphobia with panic attacks and mitral valve prolapse syndrome (MVPS). Such clinical psychiatric differences could be useful because MVPS poses potentially dangerous consequences in patients with a high rate of serious cardiac and neurological complications. The first part of the study included 35 patients, 20 of whom were confirmed MVPS. This group appeared distinguishable by the increased frequency of fear of doing something uncontrolled and, even more so, by the anger-rage symptoms manifested during the attacks. In the present study of 100 patients, 36 of whom were documented MVPS, fear of doing something uncontrolled was not greater, although attacks of anger and rage were again higher than in the other two groups and exceeded 5 % standard deviation. In all other psychological dimensions, the three groups did not differ from one another. This paper considers possible causes and consequences of symptoms seen in the MVPS.

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Long-Term Prognosis of Mitral-Valve Prolapse

Cited by 201 publications

References 25 publications

2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

Cerebral ischemic events in patients with mitral valve prolapse.

Panic Disorder Associated with Mitral Valve Prolapse: Psychosomatic Implications

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