Long-Term Prognosis for Childhood Constipation: Clinical Outcomes in Adulthood

Bongers, Marloes E.J.; Wijk, Michiel P. van; Reitsma, Johannes B.; Benninga, Marc A.

doi:10.1542/peds.2009-1009

Cited by 216 publications

(160 citation statements)

References 35 publications

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“…21,22 Because functional constipation is a long-lasting problem in many cases, long-term follow-up monitoring is necessary for better understanding of the clinical course of the disease. 4 Growing up with a chronic disorder may impede the child's development and may affect psychological and psychosocial functioning. Therefore, quality-of-life assessments, using baseline generic and before/after disease-specific quality-of-life instruments, are important secondary outcome measures.…”

Section: Discussionmentioning

confidence: 99%

“…25 The main unanswered question is why well-designed trials concerning frequently used complementary treatments are lacking for one of the most prevalent, frustrating, long-lasting, pediatric gastrointestinal disorders. 1,4,6 There are some explanations. Lack of funding may play an important role.…”

Section: Discussionmentioning

confidence: 99%

“…3 A study in a tertiary hospital showed that, despite intensive medical and behavioral therapy, 30% of patients who developed constipation before the age of 5 years continued to have severe complaints of constipation, infrequent painful defecation, and fecal incontinence beyond puberty. 4 The first step in treatment consists of education, dietary advice, and behavioral modifications. 2 If these are not effective, then laxatives are prescribed.…”

mentioning

confidence: 99%

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Nonpharmacologic Treatments for Childhood Constipation: Systematic Review

Tabbers¹,

Boluyt

Berger³

et al. 2011

Pediatrics

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OBJECTIVE:To summarize the evidence and assess the reported quality of studies concerning nonpharmacologic treatments for childhood constipation, including fiber, fluid, physical movement, prebiotics, probiotics, behavioral therapy, multidisciplinary treatment, and forms of alternative medicine. METHODS:We systematically searched 3 major electronic databases and reference lists of existing reviews. We included systematic reviews and randomized controlled trials (RCTs) that reported on nonpharmacologic treatments. Two reviewers rated the methodologic quality independently. RESULTS:We included 9 studies with 640 children. Considerable heterogeneity across studies precluded meta-analysis. We found no RCTs for physical movement, multidisciplinary treatment, or alternative medicine. Some evidence shows that fiber may be more effective than placebo in improving both the frequency and consistency of stools and in reducing abdominal pain. Compared with normal fluid intake, we found no evidence that water intake increases or that hyperosmolar fluid treatment is more effective in increasing stool frequency or decreasing difficulty in passing stools. We found no evidence to recommend the use of prebiotics or probiotics. Behavioral therapy with laxatives is not more effective than laxatives alone. CONCLUSIONS:There is some evidence that fiber supplements are more effective than placebo. No evidence for any effect was found for fluid supplements, prebiotics, probiotics, or behavioral intervention. There is a lack of well-designed RCTs of high quality concerning nonpharmacologic treatments for children with functional constipation.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Nonpharmacologic Treatments for Childhood Constipation: Systematic Review

Tabbers¹,

Boluyt

Berger³

et al. 2011

Pediatrics

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“…In this context, constipation is among the important concerns of childhood in families (3)(4)(5)(6) that refers to the frequency of solid defecation occurring with too much pressure and ache (7). In addition, gastroenterology and nutrition council of North America has defined constipation as delay or problem in defecation for more than two weeks if worries the patient or his/her parents (8,9).…”

Section: Introductionmentioning

confidence: 99%

Investigating the Effect of Nurse-Centered Strategies on Functional Chronic Constipation of Children aged 3-14 years Referring to Imam Reza Clinic of Shiraz University of Medical Sciences in 2014

et al. 2017

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Background: Functional constipation is among the most common problems of childhood. Children's life quality is affected by constipation. In addition, constipation can bring about undesirable physical and psychic consequences. However, follow-up programs can solve the problem and assure the patient about continuing treatment. Objectives: This study aimed to investigate the impact of nurse-based approaches on functional chronic constipation in children. Methods: This is a clinical trial study conducted from August to December 2013 in Imam Reza clinic. The sample size was 95 children who were randomly assigned to two groups of experimental (47 persons) and control (48 persons). The mean age in the experimen-

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“…However, 30% of patients remain symptomatic despite aggressive medical treatment [7]. Constipated children are usually advised to increase their daily physical activity.…”

Section: Introductionmentioning

confidence: 99%