Long-term persistence of human papillomavirus in environments

Ding, Dah-Ching; Chang, Ying-Cheng; Liu, Hwan-Wun; Chu, Tang-Yuan

doi:10.1016/j.ygyno.2010.11.040

Cited by 23 publications

(20 citation statements)

References 17 publications

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“…Our study shows that HPV contamination of fomites is a reality, despite careful cleaning. These findings are in accordance with previous studies 9 13 14…”

Section: Discussionsupporting

confidence: 94%

Human papillomavirus (HPV) contamination of gynaecological equipment

et al. 2015

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“…Our study shows that HPV contamination of fomites is a reality, despite careful cleaning. These findings are in accordance with previous studies 9 13 14…”

Section: Discussionsupporting

confidence: 94%

Human papillomavirus (HPV) contamination of gynaecological equipment

et al. 2015

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“…HPV is a physically stable and resistant virus with long durability 19. A recent in vitro study demonstrated that it can survive on a wet surface for at least 7 days, and carries an infection ratio of 30%.…”

Section: Discussionmentioning

confidence: 99%

Transvaginal ultrasound probe contamination by the human papillomavirus in the emergency department

et al. 2012

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“…It has been shown that HPV retains 30% of its infectivity, even after dehydration for 7 days [6]. More recently, a study has reported that HPV 16 remains infectious for at least 7 days on a wet surface [7]. These results suggest that fomites represent a possible nosocomial source of HPV infection [8].…”

Section: Introductionmentioning

confidence: 99%

High Risk HPV Contamination of Endocavity Vaginal Ultrasound Probes: An Underestimated Route of Nosocomial Infection?

et al. 2012

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BackgroundEndocavity ultrasound is seen as a harmless procedure and has become a common gynaecological procedure. However without correct disinfection, it may result in nosocomial transmission of genito-urinary pathogens, such as high-risk Human Papillomavirus (HR-HPV). We aimed to evaluate the currently recommended disinfection procedure for covered endocavity ultrasound probes, which consists of “Low Level Disinfection” (LLD) with “quaternary ammonium compounds” containing wipes.MethodsFrom May to October 2011 swabs were taken from endovaginal ultrasound probes at the Gynecology Department of the Lyon University Hospital. During the first phase (May–June 2011) samples were taken after the ultrasound examination and after the LLD procedure. In a second phase (July–October 2011) swab samples were collected just before the probe was used. All samples were tested for the presence of human DNA (as a marker for a possible transmission of infectious pathogens from the genital tract) and HPV DNA with the Genomica DNA microarray (35 different HPV genotypes).ResultsWe collected 217 samples before and 200 samples after the ultrasound examination. The PCR was inhibited in two cases. Human DNA was detected in 36 (18%) post-examination samples and 61 (28%) pre-examination samples. After the ultrasound LLD procedure, 6 (3.0%) samples contained HR-HPV types (16, 31, 2×53 and 58). Similarly, HPV was detected in 6 pre-examination samples (2.7%). Amongst these 4 (1.9%) contained HR-HPV (types 53 and 70).ConclusionOur study reveals that a considerable number of ultrasound probes are contaminated with human and HR-HPV DNA, despite LLD disinfection and probe cover. In all hospitals, where LLD is performed, the endovaginal ultrasound procedure must therefore be considered a source for nosocomial HR-HPV infections. We recommend the stringent use of high-level disinfectants, such as glutaraldehyde or hydrogen peroxide solutions.

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Long-term persistence of human papillomavirus in environments

Cited by 23 publications

References 17 publications

Human papillomavirus (HPV) contamination of gynaecological equipment

Human papillomavirus (HPV) contamination of gynaecological equipment

Transvaginal ultrasound probe contamination by the human papillomavirus in the emergency department

High Risk HPV Contamination of Endocavity Vaginal Ultrasound Probes: An Underestimated Route of Nosocomial Infection?

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