Long-term Performance of 555 Aortic Homografts in the Aortic Position

Matsuki, Osamu; Robles, Alfonso; Gibbs, Simon; Bodnár, E; Ross, Donald N.

doi:10.1016/s0003-4975(10)65895-x

Cited by 102 publications

(19 citation statements)

References 11 publications

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“…Aortic valve replacement was performed according to Ross's two-layer method with interrupted sutures for the proximal and continuous suture for the distal anastomoses [5].…”

Section: Methodsmentioning

confidence: 99%

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Long-term performance of beta-propiolactone-treated nonviable homograft for aortic valve replacement and right ventricular outflow tract reconstruction

et al. 1993

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The long-term performance of beta-propiolactone-treated homografts was clearly different between operative survivors of aortic valve replacement (n = 27) and those of right ventricular outflow tract reconstruction (n = 11). The reoperation-free survival rate at 20 years was 14.8 +/- 6.8 (standard error)% in the former and 77.8 +/- 13.9% in the latter. Even a nonviable aortic homograft can be favorably accepted as a material for right ventricular outflow tract reconstruction in contrast to the aortic position.

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“…Aortic valve replacement was performed according to Ross's two-layer method with interrupted sutures for the proximal and continuous suture for the distal anastomoses [5].…”

Section: Methodsmentioning

confidence: 99%

“…These procedures include not only AVR [3][4][5][6] or aortic root replacement [7], but also right ventricular outflow tract (RVOT) reconstruction [8] and right atrium-pulmonary artery conduit operation [91.…”

Section: Introductionmentioning

confidence: 99%

Long-term performance of beta-propiolactone-treated nonviable homograft for aortic valve replacement and right ventricular outflow tract reconstruction

et al. 1993

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“…The rates of primary tissue failure and endocarditis were 87.6 and 17.3%. The incidence of thromboembolism was 0.034% per patient year [80]. In a study of 220 homograft and 220 mechanical valve recipients, Podolec and colleagues used clinical examinations and their own developed questionnaire to find similar QOL between the two groups [33].…”

Section: Valve Type and Qolmentioning

confidence: 99%

Quality of life after aortic valve replacement

Lee¹,

Gleason

Sonnad³

2004

Expert Review of Pharmacoeconomics & Outcomes Research

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Understanding the quality of life after aortic valve replacement has become increasingly important. As aortic valve replacement numbers increase, more patients, physicians and families are affected by the subsequent quality of life. Quality of life information can inform the decision to perform aortic valve replacement and the selection of replacement valve. When reviewing quality of life results, it is important to realize that the findings are affected by the selection and quality of instruments, as many studies have not used valid or reliable instruments. Studies have shown that aortic valve replacement appears to significantly improve the quality of life of survivors, including those older than 70 years of age and even decades after the procedure, quality of life remains high. Studies have suggested that the elderly may gain as much quality of life benefit as younger patients. No consistent differences in resulting total quality of life have been observed between mechanical and bioprosthetic valves. Only one study showed some quality of life benefits of pulmonary autograft over mechanical valves. It is unclear whether minimally invasive aortic valve replacements confer better quality of life than standard aortic valve replacements. While existing quality of life studies have provided important information, more studies are needed especially as valve technology and operative techniques continue to improve. Future studies should endeavor to use validated general and disease-specific instruments and quantify the effects of demographics, preoperative clinical conditions and intraoperative variables on quality of life outcomes.

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“…Unfortunately, the durability of these homografts varies and premature shrinkage or calcification has been observed. 90 Homografts have also assumed an important place in the clinical armamentarium of the pediatrie heart surgeon when used as valve conduits, for example, in truncus re¬ pair. They have been shown to be more durable than syn¬ thetic conduits, but the valve tissue still has propensity to calcification.91…”

Section: Interrupted Aortic Archmentioning

confidence: 99%

Surgical Management of Congenital Heart Disease in the 1990s

Cohen¹

1992

Arch Pediatr Adolesc Med

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Long-term Performance of 555 Aortic Homografts in the Aortic Position

Cited by 102 publications

References 11 publications

Long-term performance of beta-propiolactone-treated nonviable homograft for aortic valve replacement and right ventricular outflow tract reconstruction

Long-term performance of beta-propiolactone-treated nonviable homograft for aortic valve replacement and right ventricular outflow tract reconstruction

Quality of life after aortic valve replacement

Surgical Management of Congenital Heart Disease in the 1990s

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