Long-term outcomes of youth who manifested the CBCL-Pediatric Bipolar Disorder phenotype during childhood and/or adolescence

Meyer, Stephanie; Carlson, Gabrielle A.; Youngstrom, Eric A.; Ronsaville, Donna S.; Martinez, Pedro E.; Gold, Philip W.; Hakak, Rashelle; Radke-Yarrow, Marian

doi:10.1016/j.jad.2008.05.024

Cited by 151 publications

(182 citation statements)

References 25 publications

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“…The CBCL-MS shows temporal stability (Papachristou et al, 2013) and construct validity in community (Papachristou et al, 2013;Zappitelli et al, 2015) and in clinical samples (Papachristou et al, 2016). Two other CBCL-derived instruments have been used to capture subthreshold manic symptoms, namely the CBCL-Dysregulation Profile (CBCL-DP) (Biederman et al, 2009;Biederman et al, 2013;Faraone et al, 2005;Meyer et al, 2009;Uchida et al, 2014) and the CBCL-Externalizing Scale (Youngstrom et al, 2006). The CBCL-MS performs similarly to these CBCL-derived instruments (Ratheesh et al, 2015) and may have a slight advantage in identifying children with mood disorders from those with disruptive behaviors (Papachristou et al, 2016).…”

Section: Baseline Assessments Of Trails Participants At Age 11 Yearsmentioning

confidence: 99%

The predictive value of childhood subthreshold manic symptoms for adolescent and adult psychiatric outcomes

Papachristou

Oldehinkel

Ormel

et al. 2017

Journal of Affective Disorders

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Section: Baseline Assessments Of Trails Participants At Age 11 Yearsmentioning

confidence: 99%

The predictive value of childhood subthreshold manic symptoms for adolescent and adult psychiatric outcomes

Papachristou

Oldehinkel

Ormel

et al. 2017

Journal of Affective Disorders

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“…Elevated scores on the anxiety/ depression, attention/hyperactivity and aggression subscales have been associated with conditions characterized by mood dysregulation (e.g., Volk and Todd, 2006;Holtmann et al 2007;McGough et al 2008;Ayer et al 2009). t scores from the aforementioned scales are generally added together with a 180 cutoff for nonclinic samples (Meyer et al 2009;Kim et al 2012), which is equivalent to *1 standard deviation from the mean. Higher cutoffs (sum ‡201), *1.5 standard deviations from the mean, are used in clinic samples (Uchida et al 2014;Brederman et al 1995).…”

mentioning

confidence: 99%

Loss of Temper and Irritability: The Relationship to Tantrums in a Community and Clinical Sample

Carlson

Danzig

Dougherty

et al. 2016

Journal of Child and Adolescent Psychopharmacology

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Background: This study explores the relationship of irritability to tantrums and loss of temper in a community and clinical sample. Methods: The community sample, recruited via commercial mailing lists, consisted of 462 6-year-olds whose parents completed the Child Behavior Checklist (CBCL), and Preschool Age Psychiatric Assessment (PAPA). Tantrums were assessed in the oppositional defiant disorder (ODD) section of the PAPA. Irritability was assessed in the depression section to identify persistently irritable and/or angry mood. The clinic sample, drawn from a child psychiatry clinic, included 229 consecutively referred 6-year-olds from 2005 through 2014 whose parents completed the CBCL and Child and Adolescent Symptom Inventory (CASI). Temper loss and irritability items came from the ODD and depression sections of the CASI, and tantrum description was taken from an irritability inventory. Children's Global Assessment Scale (CGAS) and the CBCL Dysregulation Profile were examined in both samples. Logistic and multiple regression were used to compare rates of diagnosis, CBCL subscales, CGAS, and tantrum quality between children with tantrums only and tantrums with irritability. Results: Almost half (45.9%) of clinic children had severe tantrums; only 23.8% of those were said to be irritable. In the community, 11% of children had tantrums, but 78.4% of those were called irritable. However, irritability in the clinic, although less common, was associated with aggressive tantrums and substantial impairment. In contrast, irritability was associated with only a relatively small increase in impairment in the community sample. Conclusions: Irritability may have different implications in community versus clinic samples, and tantrums assessed in the community may be qualitatively different from those seen in clinics.

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“…Studies on heterogeneous clinical populations found results in the same direction. Meyer et al (2008) analysing data from a 23 years longitudinal study on at-risk youth for psychiatric disorders (i.e. offspring of parents with mood disorders), found that CBCL-DP during childhood is associated with later anxiety disorders, ADHD, cluster-B personality disorders, bipolar disorder (BD), drug abuse and suicidal ideation (Table 1).…”

mentioning

confidence: 99%

The dysregulation profile in children and adolescents: a potential index for major psychopathology?

Negri

Brambilla

2012

Epidemiol Psychiatr Sci

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This Section of Epidemiology and Psychiatric Sciences regularly appears in each issue of the Journal to describe relevant studies investigating the relationship between neurobiology and psychosocial psychiatry in major psychoses. The aim of these Editorials is to provide a better understanding of the neural basis of psychopathology and clinical features of these disorders, in order to raise new perspectives in every-day clinical practice.Paolo Brambilla, Section Editor and Michele Tansella, Editor EPS The dysregulation profile in children and adolescents: a potential index for major psychopathology? We here review the literature on Child Behaviour Checklist-Dysregulation Profile (CBCL-DP) index, which potentially represents a developmental profile of major psychopathology in early adulthood. The understanding of the neural underpinnings of children and adolescents with altered regulation of affect and behaviour may ultimately help in planning strategies to prevent psychiatric syndromes during development. In the past few years, it has been proposed that the sum of T scores in three Syndromes scales (i.e. Aggressive Behaviour, Anxious/Depressed and Attention Problems) could be used to identify CBCL-Juvenile Bipolar Disorder index (CBCL-JBD index; Biederman et al. 2009). However, the diagnostic value of this index in detecting JBD has been disconfirmed afterwards because of its low sensitivity and specificity (Volk & Todd, 2007). Recently, the CBCL-JBD index has been renamed as 'CBCL-Dysregulation Profile' (CBCL-DP) index, as it better detects children with 'a persisting deficit of selfregulation of affect and behaviour . Several studies confirmed that CBCL-DP does not represent an early manifestation of JBD and it is not linked to a specific psychiatric diagnosis (Ayer et al. 2009

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Long-term outcomes of youth who manifested the CBCL-Pediatric Bipolar Disorder phenotype during childhood and/or adolescence

Cited by 151 publications

References 25 publications

The predictive value of childhood subthreshold manic symptoms for adolescent and adult psychiatric outcomes

The predictive value of childhood subthreshold manic symptoms for adolescent and adult psychiatric outcomes

Loss of Temper and Irritability: The Relationship to Tantrums in a Community and Clinical Sample

The dysregulation profile in children and adolescents: a potential index for major psychopathology?

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