Long-term outcomes of the Woven EndoBridge device for treatment of intracranial aneurysms: A systematic review and meta-analysis

Abstract

Background The Woven EndoBridge (WEB) has been specifically developed to manage wide neck bifurcation intracranial aneurysms. A wide range of aneurysm occlusion rates and device-related complications are reported in different papers, and a lack of collective evidence in this regard. Objective To clarify the long-term efficacy and safety outcomes of intracranial aneurysm treatment with WEB devices. Methods A systematic literature search was performed on PubMed, Scopus, Web of Science, and Embase databases on April 25, 2023. Considering the eligibility criteria, all the studies reporting the outcomes of the intracranial aneurysm treatment with WEB device at 1 and/or more than 1 year were included. Data elements of interest were extracted and analyzed using R software version 4.2.1. Results Twenty-seven articles were included. Complete occlusion rate was 56.85%, 67.10%, and 56.34% at one year, beyond one year, and at/beyond two years of follow-up, respectively. Adequate occlusion rate was 87.11% at one year, 91.16% beyond one year, and 88.87% at/beyond two years of follow-up. WEB compression and aneurysm recurrence rates increased from 17.62% and 0.58% at one year to 42.59% and 18.99% beyond one year of follow-up, respectively. An increase in retreatment rate from 3.45% at one year to 7.15% beyond one year of follow-up was found. Conclusion The current study supports the long-term efficacy of WEB devices for the treatment of intracranial aneurysms. However, an increase in WEB compression, aneurysm recurrence, and retreatment rates beyond one year reveals the importance of follow-ups after the first year of WEB placement.

Endovascular treatment of intracranial internal carotid artery bifurcation region aneurysms

“…The outcomes had to be extracted from those studies containing ICA bifurcation region aneurysms ( 79 , 81 , 84–87 ). In general, WEB deployment for ICA bifurcation region aneurysms can yield good outcomes in approximately 80% of cases, as shown in the studies of Pierot et al ( 84 ), Dmytriw et al ( 81 ), Cortese et al ( 85 ), Pierot et al ( 79 ), Lee et al ( 86 ) and Hassankhani et al ( 87 ).…”

“…Currently, there are no specialized studies that aim to treat ICA bifurcation aneurysms with the WEB device. The outcomes had to be extracted from those studies containing ICA bifurcation region aneurysms (79,81,(84)(85)(86)(87). In general, WEB deployment for ICA bifurcation region aneurysms can yield good outcomes in approximately 80% of cases, as shown in the studies of Pierot et al ( 84 Recently, more exciting results have been achieved.…”

Endovascular Treatment of Bifurcation Aneurysms with the Woven EndoBridge: Product Features and Selected Results of Off-Label Use

“… 33) Hassankhani et al conducted a review in 2023 of 27 articles, in which they noted that beyond 2 years, there was an increase in recurrent cases and retreatments. 34) Device shape changes, specifically the introduction of WEB compression, were observed in 43% of the cases, recurrence in 19%, and retreatment increased to 7.2% after 1 year. 34) …”

“… 34) Device shape changes, specifically the introduction of WEB compression, were observed in 43% of the cases, recurrence in 19%, and retreatment increased to 7.2% after 1 year. 34) …”