Long-Term Outcomes of Repeat Hepatic Resection in Patients with Recurrent Hepatocellular Carcinoma and Analysis of Recurrent Types and Their Prognosis: A Single-Center Experience in China

Huang, Zhiyong; Liang, Benjia; Xiong, Min; Zhan, Daqian; Wei, Shuang; Wang, Guoping; Chen, Yi-fa; Chen, Xiaoping

doi:10.1245/s10434-012-2269-7

Cited by 108 publications

(126 citation statements)

References 34 publications

Supporting

Mentioning

112

Contrasting

Order By: Relevance

“…For recurrent HCCs, MO patients have been shown to have a better outcome than IM patients (Yasui et al, 1997;Huang et al, 2012). Additionally, a recurrence-free time of more than 18 months after the initial hepatic resection has been suggested as a cutoff point to differentiate MO from IM in clinical practice (Huang et al, 2012).…”

Section: Discussionmentioning

confidence: 99%

“…Additionally, a recurrence-free time of more than 18 months after the initial hepatic resection has been suggested as a cutoff point to differentiate MO from IM in clinical practice (Huang et al, 2012). However, in another study, a time of 2 years was suggested (Portolani et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

“…The MO recurrence of HCC is new and different from the primary lesion, but for IM, the recurrence is derived from the primary tumor. Patients with MO have better outcomes than those with IM (Yasui et al, 1997;Huang et al, 2012). Many studies (Oda et al, 1992; Liver Cancer Study Group of Japan, 1997;Yamamoto et al, 1999;Chen et al, 2000;Nomoto et al, 2002;Okamoto et al, 2006;Nomoto et al, 2007;Li et al, 2008) have examined the differentiation of the origins of recurrent HCC, also known as metachronous multiple HCC, because the original type is important for the preoperative assessment, determining the treatment modality and predicting patient prognosis.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Clinicopathologic Characteristics and Prognoses for Multicentric Occurrence and Intrahepatic Metastasis in Synchronous Multinodular Hepatocellular Carcinoma Patients

Su²,

Peng³

et al. 2013

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinicopathologic Characteristics and Prognoses for Multicentric Occurrence and Intrahepatic Metastasis in Synchronous Multinodular Hepatocellular Carcinoma Patients

Su²,

Peng³

et al. 2013

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

“…The 5-year cumulative recurrence rates are 77%-100%, and 80%-95% of recurrences are confined to the remnant liver (Huang et al, 2012). Effective therapeutic strategies for intrahepatic recurrence are critical in prolonging survival after liver resection.…”

Section: Recurrent Hepatocellular Carcinomamentioning

confidence: 99%

“…The 5-year survival rate after repeat liver resection varies from 23% to 69% in different studies, suggesting that repeat liver resection results in good outcomes in selected patients (Huang et al, 2012). However, the selection criteria of repeat liver resection for recurrent HCC remain vague and controversial.…”

Section: Recurrent Hepatocellular Carcinomamentioning

confidence: 99%

Surgical treatment of hepato-pancreato-biliary disease in China: the Tongji experience

Zhang

Wang

Luo

et al. 2016

Sci. China Life Sci.

Self Cite

View full text Add to dashboard Cite

Hepato-pancreato-biliary (HPB) tumors are common in China. However, these tumors are often diagnosed at intermediate/advanced stages because of the lack of a systemic surveillance program in China. This situation creates many technical challenges for surgeons and increases the incidence of postoperative complications. Therefore, Dr. Xiao-Ping Chen has made many important technical improvements, such as Chen's hepatic portal occlusion method, the anterior approach for liver resection of large HCC tumors, the modified technique of Belghiti's liver-hanging maneuver, inserting biliary-enteric anastomosis technique, and invaginated pancreaticojujunostomy with transpancreatic U-sutures. These techniques are simple, practical, and easy to learn. Owing to these advantages, complicated surgical procedures can be simplified, and the curative effects are greatly improved. These improved techniques have been widely applied in China and will benefit many additional patients. In this review, we introduce our experience of surgically treating intermediate/advanced hepatocellular carcinoma (HCC), hilar cholangiocarcinoma (HC), and pancreatic carcinoma, mainly focusing on technical innovations established by Dr. Chen in HPB surgery. hepatocellular carcinoma, liver transplantation, hilar cholangiocarcinoma, pancreaticojejunostomy

show abstract

Preoperative lymphocyte‐to‐monocyte ratio is useful for stratifying the prognosis of hepatocellular carcinoma patients with a low Cancer of the Liver Italian Program score undergoing curative resection

Shioiri

Ishizuka

Park

et al. 2019

Annals of Gastroent Surgery

View full text Add to dashboard Cite

Background and Aim Although the Cancer of the Liver Italian Program (CLIP) score is useful for prognostication of patients with hepatocellular carcinoma (HCC), a previous study has reported that the CLIP score was unable to stratify the postoperative outcomes of HCC patients in whom the score was low (0‐1). Recent studies have reported that the preoperative lymphocyte‐to‐monocyte ratio (LMR) is useful for prognostication of patients with various cancer. Methods We reviewed 329 HCC patients with a low CLIP score (0‐1) undergoing curative resection. This study had the approval of the Institutional Review Board (28068). Multivariate analyses were carried out to detect clinical factors correlating with overall survival (OS). Kaplan‐Meier analysis and the log‐rank test were used for comparison of OS. Results Multivariate analysis showed that LMR (<4.35/≥4.35) was significantly associated with OS (hazard ratio [HR], 2.022; 95% CI, 1.141‐3.583; P = 0.016) as well as portal vein invasion (HR, 2.410; 95%CI, 1.258‐4.618; P = 0.008). Kaplan‐Meier analysis and the log‐rank test showed a significant difference in OS and relapse‐free survival between patients with high LMR and those with low LMR. Conclusion Preoperative LMR is useful for stratifying the prognosis of HCC patients with a low CLIP score (0‐1) undergoing curative resection.

show abstract

Long-Term Outcomes of Repeat Hepatic Resection in Patients with Recurrent Hepatocellular Carcinoma and Analysis of Recurrent Types and Their Prognosis: A Single-Center Experience in China

Abstract: Repeat hepatic resection resulted in much higher survival rates in the MO patients than in the IM patients. Repeat hepatic resection could be recommended for those patients in whom the recurrent HCC occurs more than 18 months after initial resection.

Cited by 108 publications

References 34 publications

Clinicopathologic Characteristics and Prognoses for Multicentric Occurrence and Intrahepatic Metastasis in Synchronous Multinodular Hepatocellular Carcinoma Patients

Clinicopathologic Characteristics and Prognoses for Multicentric Occurrence and Intrahepatic Metastasis in Synchronous Multinodular Hepatocellular Carcinoma Patients

Surgical treatment of hepato-pancreato-biliary disease in China: the Tongji experience

Preoperative lymphocyte‐to‐monocyte ratio is useful for stratifying the prognosis of hepatocellular carcinoma patients with a low Cancer of the Liver Italian Program score undergoing curative resection

Contact Info

Product

Resources

About