Long-Term Outcomes of Laparoscopic Adrenalectomy for Adrenal Masses

Kang, Thomas; Gridley, Asahel; Richardson, William

doi:10.1089/lap.2014.0430

Cited by 10 publications

(9 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Tumor size on cross-sectional imaging is the best predictor of malignancy of an adrenal mass, with a 4-cm cutoff and 93% sensitivity [23]. An abnormal radiological appearance was reported to be superior to tumor size for predicting malignancy [24]. Nonetheless, use of laparoscopy for aggressive malignant tumors remains controversial due to the low recurrence-free survival rate [25].…”

Section: Discussionmentioning

confidence: 99%

The Pathologic Point of View of Laparoscopic Adrenalectomy in the Era of Radiologic Imaging: A Multicenter Retrospective Study

Tonyalı

Ataç²,

Eroğlu³

et al. 2016

Urol Int

View full text Add to dashboard Cite

Introduction/Aim: This study aimed to determine if laparoscopic adrenalectomy (LA) is feasible for the treatment of adrenal malignancies and metastasis, and to review the final pathology findings in order to clarify the indications for surgery. Materials and Method: The medical records of all patients that underwent LA at 3 university hospitals between January 1, 2008, and May 1, 2015, were retrospectively reviewed. Results: In total, 189 laparoscopic adrenalectomies were completed successfully. Mean duration of surgery was 79.3 ± 38.6 min and mean estimated intraoperative blood loss was 39.9 ml. Intraoperatively, 4 patients had major complications: spleen injury (n = 1), renal vein injury (n = 2) and diaphragm injury (n = 2). Histopathological examination showed that there were 20 different types of lesions. Surgical margins (SMs) were tumor free in 95.2% of the patients. Moreover, SMs were tumor free in all patients with adrenocortical carcinomas; however, positive margins were noted in 7 of 23 patients (30.4%) with malignant adrenal tumors. Conclusions: The present findings support the use of laparoscopy for metastatic adrenal masses, despite a high positive margin rate. LA is a safe, feasible and cost-effective procedure for the management of benign and malignant adrenal masses.

show abstract

Section: Discussionmentioning

confidence: 99%

The Pathologic Point of View of Laparoscopic Adrenalectomy in the Era of Radiologic Imaging: A Multicenter Retrospective Study

Tonyalı

Ataç²,

Eroğlu³

et al. 2016

Urol Int

View full text Add to dashboard Cite

show abstract

“…The search yielded 854 references for abstract screening of which 26 studies (19,20,21,22,23,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49) were included in this systematic review (Fig. 1).…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…Our search identified eight studies reporting on clinical outcomes before and after adrenalectomy in patients with NF adrenal tumors (19,31,34,35,37,39,47,48). In five of these studies (54 patients with HTN), 21 patients had improvement of BP control after adrenalectomy (42%, 95% CI: 21-63%), Supplementary Fig.…”

Section: Metabolic Outcome In Patients With Nf Adrenal Tumors Comparimentioning

confidence: 99%

“…Only six studies aimed to compare the effect of adrenalectomy on comorbidities in both SCS and NF populations (19,31,35,37,39,47). Taking into consideration the small sample size, we did not find statistically significant differences between patients with SCS and NF adrenal tumors with regard to impact of adrenalectomy on HTN (39 SCS and 43 NF patients), DM2 (19 SCS and 14 NF patients), obesity (16 SCS and 14 NF patients) and dyslipidemia (22 SCS and 23 NF patients) (data not shown).…”

Section: Metabolic Outcome Comparing Adrenalectomy In Patients With Smentioning

confidence: 99%

See 1 more Smart Citation

THERAPY OF ENDOCRINE DISEASE: Improvement of cardiovascular risk factors after adrenalectomy in patients with adrenal tumors and subclinical Cushing’s syndrome: a systematic review and meta-analysis

Bancos

Alahdab

Crowley

et al. 2016

European Journal of Endocrinology

142

110

View full text Add to dashboard Cite

Objective: Beneficial effects of adrenalectomy on cardiovascular risk factors in patients with subclinical Cushing's syndrome (SCS) are uncertain. We sought to conduct a systematic review and meta-analysis with the following objectives: (i) determine the effect of adrenalectomy compared with conservative management on cardiovascular risk factors in patients with SCS and (ii) compare the effect of adrenalectomy on cardiovascular risk factors in patients with SCS vs those with a nonfunctioning (NF) adrenal tumor. Methods: MEDLINE In-Process & Other Non-Indexed Citations, MEDLINE, EMBASE and Cochrane Central Register of Controlled Trial were searched on 17 November 2015. Reviewers extracted data and assessed methodological quality in duplicate. Results: We included 26 studies reporting on 584 patients with SCS and 457 patients with NF adrenal tumors. Studies used different definitions of SCS. Patients with SCS undergoing adrenalectomy demonstrated an overall improvement in cardiovascular risk factors (61% for hypertension, 52% for diabetes mellitus, 45% for obesity and 24% for dyslipidemia). When compared with conservative management, patients with SCS undergoing adrenalectomy experienced improvement in hypertension (RR 11, 95% CI: 4.3-27.8) and diabetes mellitus (RR 3.9, 95% CI: 1.5-9.9), but not dyslipidemia (RR 2.6, 95% CI: 0.97-7.2) or obesity (RR 3.4,. Patients with NF adrenal tumors experienced improvement in hypertension (21/54 patients); however, insufficient data exist for comparison to patients with SCS. Conclusions: Available low-to-moderate-quality evidence from heterogeneous studies suggests a beneficial effect of adrenalectomy on cardiovascular risk factors in patients with SCS overall and compared with conservative management.

show abstract

“…Both the safety and feasibility aspects have been proven along with undisputed postoperative benefits demonstrated over open approach. [1][2][3] However, it is sometimes not technically feasible or safe for large, vascular, or suspicious adrenal masses. Successful attempts in laparoscopic approach for large adrenal tumors have only been reported in small case series.…”

Section: Introductionmentioning

confidence: 99%

Salvage Technique for Intraoperative Hemorrhage during Laparoscopic Resection of Large Pheochromocytoma: A Case Report and Literature Review

Singaporewalla¹,

Lee²,

Tan³

2017

World Journal of Endocrine Surgery

View full text Add to dashboard Cite

Aim:We described the use of a hand-port assisted laparoscopic adrenalectomy for excising a large 10 cm vascular left adrenal pheochromocytoma. The useful technical tips and important pitfalls to avoid for a successful outcome are discussed in this article. Introduction:A 64-year-old man who was investigated for microalbuminuria was found to have a 10-cm left adrenal mass. Blood investigation and imaging confirmed it to be a pheochromocytoma.

show abstract

Long-Term Outcomes of Laparoscopic Adrenalectomy for Adrenal Masses

Cited by 10 publications

References 17 publications

The Pathologic Point of View of Laparoscopic Adrenalectomy in the Era of Radiologic Imaging: A Multicenter Retrospective Study

The Pathologic Point of View of Laparoscopic Adrenalectomy in the Era of Radiologic Imaging: A Multicenter Retrospective Study

THERAPY OF ENDOCRINE DISEASE: Improvement of cardiovascular risk factors after adrenalectomy in patients with adrenal tumors and subclinical Cushing’s syndrome: a systematic review and meta-analysis

Salvage Technique for Intraoperative Hemorrhage during Laparoscopic Resection of Large Pheochromocytoma: A Case Report and Literature Review

Contact Info

Product

Resources

About