Long-term outcomes of initial trabeculectomy in glaucoma associated with granulomatous and non-granulomatous uveitis

Abstract

To evaluate the outcomes of initial trabeculectomy in granulomatous and non-granulomatous uveitis. MethodsRetrospective comparative study of 68 eyes that underwent an initial trabeculectomy. ResultsThe mean follow-up was 74.18 and 74.86 months in both groups (p = 0.95). The intraocular pressure decreased from 40.03 mmHg (± 7.2) and 36.48 mmHg (± 11.3) to 14.00 mmHg (± 6.2) and 13.48 mmHg (± 5.7), the number of medications decreased from 3.73 (± 0.7) and 3.58 (± 0.9) to 1.00 (± 1.4) and 1.13 (± 1.4) on the last follow-up (p < 0.01) in the granulomatous and non-granulomatous groups, respectively.More eyes in the granulomatous uveitis group developed delayed postoperative complications like cataract, transient hypotony and glaucoma progression. Success rates were 64.9 and 71.0%, while failure rates were 35.1 and 29.0% in both groups (p = 0.84). ConclusionsTrabeculectomy seems to have comparable IOP control and survival in granulomatous and nongranulomatous uveitis. Nevertheless, more eyes in the granulomatous uveitis group developed late onset complications.

One Year Results of the Preserflo MicroShunt Implantation for Refractory Glaucoma

“…Almobarak et al 26 describe a mean IOP in the eyes with uveitic glaucoma after trabeculectomy of 14 ± 6.2 mm Hg. This value is higher than the postoperative mean IOP of uveitic glaucoma in our study (10.4 ± 1.1 mm Hg).…”