Long-Term Outcomes of Carinal Sleeve Resection in Non-Small Cell Lung Cancer

Sezen, Celal Buğra; Kocatürk, Celalettin; Bilen, Salih; Kalafat, Cem Emrah; Cansever, Levent; Dinçer, Seyyit İbrahim; Bedirhan, Mehmet Ali

doi:10.1055/s-0039-1679959

Cited by 12 publications

(27 citation statements)

References 17 publications

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“…Diabetes is an important predisposing factor for anastomotic complications. It increases the complication rate by 3% [16,17]. When we evaluated complication rates in terms of diabetes mellitus, various complications were observed in 4 of the five diabetic patients (p = 0.023).…”

Section: Discussionmentioning

confidence: 98%

“…All rights reserved. determined to be reducing the tensile force on the anastomosis, not disrupting the vasculature, and practicing meticulous dissection [16]. Release techniques are used to reduce the tensile force on anastomoses.…”

Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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Prognostic factors associated with morbidity and mortality after surgery for postintubation tracheal stenosis

Ceritoğlu¹,

Sezen²,

Aker³

et al. 2020

Curr Thorac Surg

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To cite this article: Ceritoğlu A, Sezen CB, Aker C, Girgin O, Akın H. Prognostic factors associated with morbidity and mortality after surgery for postintubation tracheal stenosis. Curr Thorac Surg 2020; 5(1): 16-22. ABSTRACT Background:In this study, we reviewed the treatment, follow-up, and prognostic factors associated with complications in patients who underwent tracheal resection due to postintubation tracheal stenosis (PETS), in light of the literature. Materials and Methods: Twenty-five patients who were operated for PETS between June 2012 and June 2017 were retrospectively evaluated. The patients' postoperative complications and prognostic factors affecting mortality were examined.Results: There was 11 female (44%) and 14 male (56%) patients. Eight patients (32%) had comorbidities.The mean prolonged intubation time was 47.4 ± 55.0 minutes. Eight patients (32%) developed postoperative morbidity. The main prognostic factors associated with morbidity were the length of the stenotic area and the presence of endocrine and respiratory comorbidities (p<0.05). Tracheal fistulae were observed in 2 patients. The postoperative mortality rate was 8% (n=2). One patient with fistula died on postoperative day 2, while another patient died at postoperative three months due to cardiac failure. No significant factor was identified in relation to the development of tracheal fistulae. Conclusions:The most important factor associated with complications was the presence of endocrine comorbidities. Although tracheal surgery results in high rates of postoperative morbidity and mortality, we believe these risks can be reduced by experienced surgeons and appropriate patient selection.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

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Prognostic factors associated with morbidity and mortality after surgery for postintubation tracheal stenosis

Ceritoğlu¹,

Sezen²,

Aker³

et al. 2020

Curr Thorac Surg

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“…Immunohistochemical evaluation of these tumors results in the detection of SqCC as an epithelial component [5,10,15,18,21,22]. Koss et al [18] noted that epithelial components of these tumors are primarily SqCC (46%) and adenocarcinoma (31%).…”

Section: Discussionmentioning

confidence: 99%

“…Pulmonary carcinosarcomas are commonly seen in middle-aged men and are associated strongly with smoking. The World Health Organization classifies these malignancies under the subgroup of sarcomatoid carcinomas, and they have a poorer prognosis than do non-small cell lung carcinomas [4,5]. Preoperatively, diagnostic and interventional procedures are limited.…”

Section: Introductionmentioning

confidence: 99%

Primary pulmonary carcinosarcomas: postoperative results and survival analysis

Doğru¹,

Sezen²,

Aker³

et al. 2020

Curr Thorac Surg

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Background: In this study, we assessed the long-term results of 11 patients that we operated due to primary pulmonary carcinosarcoma in the light of literature. Materials and Methods: We analyzed 11 patients' data, who underwent lung resection, retrospectively between 2009-2018. The comorbidity score was calculated according to the modified Charlson Comorbidity Index (CCI). Results: Of the 11 patients in the study, 10 (90.9%) were male, one was female (%9.1), and the median age of the subjects was 59.18 ± 8.86. Nine of the patients (81.8%) underwent lobectomy, two of them (18.1%) underwent pneumonectomy. As a cellular type, 6 of them have squamous cell carcinoma, 5 of them have adenocarcinoma. Furthermore, as a sarcomatous component, we detected 6 of the patients have spindle cell sarcoma, 3 of them have chondrosarcoma, one of them has osteosarcoma. and one patient has angiosarcoma. Nine complications occur postoperatively in 5 patients (45.9%). The fiveyear survival rate was 36.4%. Patients who received adjuvant chemotherapy, the five-year survival rate was 50%, meanwhile, patients who did not receive adjuvant chemotherapy five-year survival rate was not detected (P = 0.006). If the patients have CCI score is two and below their five-year survival rate was 44.4%, meanwhile if the patients have CCI score is two and above their five-year survival rate was not detected (P = 0.018). Recurrence or metastasis was diagnosed in 7 patients (63.6%) postoperatively. The 5-year disease-free survival rate is 12.5%. Conclusions: Surgical resection is still the most effective treatment modality for these patients. Adjuvant therapy and comorbidity are detected most important factors that affect the survival rate.

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