Long-term outcomes following VATS lobectomy for non-small cell bronchogenic carcinoma

Walker, William S.; Codispoti, Massimiliano; Soon, Sing Yang; Stamenkovic, Steven; Carnochan, Fiona M.; Pugh, G.C.

doi:10.1016/s1010-7940(02)00814-x

Cited by 239 publications

(137 citation statements)

References 20 publications

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“…In addition, the extended survival may be further exaggerated by the limited number of patients available (44,45). We consi dered that patient bias may be a critical bias, and it should have influence on survival.…”

Section: Discussionmentioning

confidence: 94%

Video-assisted thoracoscopic surgery versus open lobectomy for stage I lung cancer: A meta-analysis of long-term outcomes

Liu

2012

Experimental and Therapeutic Medicine

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Abstract. The present study aimed to evaluate the evidence comparing video-assisted thoracoscopic surgery (VATS) and open lobectomy for the treatment of stage I lung cancer using meta-analytical techniques. A literature search was undertaken until July 2011 to identify comparative studies evaluating survival rates, recurrence rates and complications. Pooled odds ratios (OR) and 95% confidence intervals (95% CI) were calculated with either the fixed-or random-effects model. These studies included a total of 1, IntroductionLung cancer is the most common malignant tumor in the world. With the improvement in diagnostic technology, more and more stage I lung cancer is identified. Video-assisted thoracoscopic surgery (VATS) was first reported by Levi et al in 1990 (1). The inital clinical reports on video-assisted thoracoscopic surgery lobe ctomy, published from 1993 onward, were either preliminary or involved a small number of patients, which indicated the feasibility and safety of VATS lobectomy (2-6). Since then, VATS has become an attractive surgical procedure for benign diseases, due to its low invasiveness (7,8). As the experience with VATS for benign diseases increased, VATS was gradually adopted for the treatment of lung cancer. Thereafter, VATS lobectomy for elderly patients and series involving a larger number of patients were reported (9-14). VATS lobectomy is now accepted, if not universally, at least as an alternative surgical option for early-stage lung cancer.The advantages of VATS lobectomy, which include less pain and better pulmonary function in the early postoperative period, have been previously reported. However, there are various controversies regarding the prognosis of VATS vs. open lobectomy for stage I lung cancer. Immune system function in the early postoperative period was found to be better preserved in patients who underwent VATS lobectomy. Curability after VATS lobectomy was also reported to be similar to the generally accepted curability rate after open lobectomy. Several investigators reported that the survival rate after VATS lobectomy was similar to that after open lobectomy. Sawada et al (15), Sugiura et al (16), Tashima et al (17) and Flores et al (18) reported that there was no statistically significant difference in survival between the VATS and open lobectomy in early-stage lung cancer. However, this meta-analysis showed that VATS had significantly better survival rates in terms of overall survival at 5 years. Materials and methodsStudy selection. Electronic searches were performed of the MEDLINE, Cochrane Controlled Trial Register (CENTRAL) and EMBASE databases until July 2011. The following Mesh search headings were used: (VATS, video-assisted thoracoscopic or video-assisted thoracoscopic surgery), (open or conventional or standard lobectomy), (lung cancer or lung carcinoma), (randomized controlled trials) and (comparative study) in English (Fig. 1).Data extraction and quality assessment. Data were extracted by three independent observers using standardized forms. The rec...

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Section: Discussionmentioning

confidence: 94%

Video-assisted thoracoscopic surgery versus open lobectomy for stage I lung cancer: A meta-analysis of long-term outcomes

Liu

2012

Experimental and Therapeutic Medicine

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“…Blazeby et al (11) evaluated the quality of life of esophageal cancer patients who received surgery or palliative treatment using EORTC QLQ-C30 and observed that the quality of life of the former was significantly higher compared to that of the latter, suggesting that surgical treatment may be a preferred choice for patients with esophageal cancer. Studies on the effect of VATS on the quality of life are currently more focused on patients with lung cancer (12,13). To the best of our knowledge, this is the first study on the effect of VATS on the quality of life of patients with esophageal cancer.…”

Section: Discussionmentioning

confidence: 99%

Assessment of health-related quality of life of patients with esophageal squamous cell carcinoma following esophagectomy using EORTC quality of life questionnaires

Shen

Wang

et al. 2014

Molecular and Clinical Oncology

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Abstract. Esophageal cancer is one of the leading causes of cancer-related mortality and surgery is currently the main treatment modality for resectable esophageal cancer. To assess health-related quality of life (HRQL) of patients with esophageal squamous cell carcinoma (ESCC) following esophagectomy, 62 consecutive patients with middle ESCC were randomly assigned into hand video-assisted thoracoscopic surgery (HVATS) (n=33) and Ivor-Lewis surgery (ILS) (n=29) groups. Quality of life questionnaires (QLQ)-C30 and QLQ-OES18, published by the European Organization for Research and Treatment of Cancer, were used prior to treatment and at regular intervals until 6 months following surgery. The results of QLQ-C30 and QLQ-OES18 demonstrated that i) patients with comorbidities and advanced tumor stage (III-IV) exhibited increased risk of poor HRQL, while their gender, age, body mass index and anastomosis location were not associated with HRQL at 6 months after surgery; ii) all the patients had worse functional, symptom and global scores within 6 months after surgery; iii) patients in the HVATS group had similar baseline functional and symptom scores to those of patients in the ILS group; however, their functional and global scores were higher and their symptom scores were lower compared to those of patients in the ILS group; iv) the HRQL of patients in the HVATS group returned to preoperative levels within a shorter time period compared to patients in the ILS group. There were significant differences in global health, physical functioning, fatigue and pain scales between the two groups. In QLQ-OES18, the dysphagia and gastroesophageal reflux scales were improved in both the HVATS and ILS groups, but no significant differences were observed between the two groups. In addition, the overall survival rate was similar in the two groups. Taken together, our findings indicated that HVATS is a safe procedure, associated with less disturbance to short-term HRQL compared to ILS. Therefore, it appears reasonable to select HVATS for patients with early-stage middle esophageal cancer.

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“…A VATS approach does not compromise survival for lung cancer patients. 5-year survival for VATS lobectomy show outcomes that are typically expected for surgical treatment of lung cancer (McKenna et al, 2006;Walker et al, 2003;Yamamoto et al, 2010;Rueth & Andrade, 2010). With no proven difference in stage specific survival VATS lobectomy can be recommended for clinical stage I and II non-small cell lung cancer.…”

Section: Survivalmentioning

confidence: 99%

“…Table 1 shows typical complications after VATS lobectomy. Mortality rates for VATS lobectomy vary from 0% to 2,6% (McKenna et al, 2006;Roviario et al, 2003;Walker et al, 2003).…”

Section: Complicationsmentioning

confidence: 99%

The Era of VATS Lobectomy

Veit¹

2012

Topics in Thoracic Surgery

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Long-term outcomes following VATS lobectomy for non-small cell bronchogenic carcinoma

Cited by 239 publications

References 20 publications

Video-assisted thoracoscopic surgery versus open lobectomy for stage I lung cancer: A meta-analysis of long-term outcomes

Video-assisted thoracoscopic surgery versus open lobectomy for stage I lung cancer: A meta-analysis of long-term outcomes

Assessment of health-related quality of life of patients with esophageal squamous cell carcinoma following esophagectomy using EORTC quality of life questionnaires

The Era of VATS Lobectomy

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